Unusual uterine metastasis of plasmablastic lenfoma: a case report

Yıl 2019, Cilt: 5 Sayı: 6, 1020 - 1023, 04.11.2019

Suat Karataş Tayfur Çift Veysel Şal Meltem Tekelioğlu Özlem Ton

https://doi.org/10.18621/eurj.455365

Cited By: 1

Öz

Plasmablastic
lenfoma (PBL) is a diffuse large B-cell lymphoma (DLBCL)’s variant form that is
especially reported in HIV-infected patients. PBL is a rare entity seen most
commonly in the setting of immunocompromise. However, this disease may present
in extraoral sites in which the genital tract appears to be the less common. Here
we present a patient with uterine and fallopian mass diagnosed PBL. A 51-year-old
multipara (G6P4C2) woman with a chief complaint of irregular vaginal bleeding
was presented to our outpatient clinic. She had a prior history of breast
cancer treated by right mastectomy and adjuvant chemotherapy.Transvaginal
ultrasonography and magnetic resonance imaging both showed an uterine mass
thought to be leiomyoma, which 4×3 cm in size on the anterior wall of uterin
corpus. The pathology result of the mass was found to be plasmablastic
lymphoma. Genital involvement also appears to be last but possible site option to
find PBL focus in immunocompetent patients. 

Anahtar Kelimeler

Plasmablastic lymphoma, uterine mass, surgery

Kaynakça

• [1] El Fakih R, Almahayni M, Alsermani M. Plasmablastic lymphoma presenting as exophytic skin lesions. Hematol Oncol Stem Cell Ther 2017;10:164-5.
• [2] Delecluse HJ, Anagnostopoulos I, Dallenbach F, Hummel M, Marafioti T, Schneider U, et al. Plasmablastic lymphomas of the oral cavity: a new entity associated with the human immunodeficiency virus infection. Blood 1997:15;89:1413-20.
• [3] Lee OJ, Kim KW, Lee GK. Epstein-Barr virus and human immunodeficiency virus-negative oral plasmablastic lymphoma. J Oral Pathol Med 2006;35:382-4.
• [4] Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood 2016;127:2375-90.
• [5] Morton LM, Wang SS, Devesa SS, Hartge P, Weisenburger DD, Linet MS. Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001. Blood 2006;107:265-76.
• [6] Dittus C, Sarosiek S. A case of HIV-negative plasmablastic lymphoma of the bone marrow with a unique immunophenotype. Clin Case Rep 2017;5:902-4.
• [7] Han X, Duan M, Hu L, Zhou D, Zhang W. Plasmablastic lymphoma: Review of 60 Chinese cases and prognosis analysis. Medicine (Baltimore) 2017;96:e5981.
• [8] Gong J, Alkan S, Anand S. A case of cutaneous plasmablastic lymphoma in HIV/AIDS with disseminated cryptococcus. Case Rep Oncol Med 2013;2013:862585.
• [9] Rafaniello Raviele P, Pruneri G, Maiorano E. Plasmablastic lymphoma: a review. Oral Dis 2009;15:38-45.
• [10] Komaranchath AS, Haleshappa RA, Kuntegowdenahalli LC, Kumar RV, Dasappa L, Babu G. Plasmablastic lymphoma of the gastrointestinal tract: A rare entity with a dismal prognosis. Indian J Cancer 2016;53:529-33.