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Yıl 2020, Cilt: 6 Sayı: 2, 120 - 129, 04.03.2020
https://doi.org/10.18621/eurj.466831

Öz

Kaynakça

  • 1. Beighton P, Solomon L, Soskolne C. Articular mobility in an African population. Ann Rheum Dis 1973;32:413-8.
  • 2. Simmonds JV, Herbland A, Hakim A, Ninis N, Lever W, Aziz Q, et al. Exercise beliefs and behaviours of individuals with Joint Hypermobility syndrome/Ehlers-Danlos syndrome-hypermobility type. Disabil Rehabil 2019;41:445-55.
  • 3. Krahe AM, Adams RD, Nicholson LL. Features that exacerbate fatigue severity in joint hypermobility syndrome/Ehlers-Danlos syndrome-hypermobility type. Disabil Rehabil 2018;40:1989-96.
  • 4. Malfait F, Francomano C, Byers P, Belmont J, Berglund B, Black J,et al. The 2017 international classification of the Ehlers-Danlos syndromes. Am J Med Genet C Semin Med Genet 2017;175:8-26.
  • 5. Bovet C, Carlson M, Taylor M. Quality of life, unmet needs, and iatrogenic injuries in rehabilitation of patients with Ehlers-Danlos Syndrome hypermobility type/Joint Hypermobility Syndrome. Am J Med Genet A 2016;170:2044-51.
  • 6. Gerwin RD. Benign joint hypermobility is not benign. Myopain 2015;23:11-2.
  • 7. Fikree A, Aktar R, Morris JK, Grahame R, Knowles CH, Aziz Q. The association between Ehlers-Danlos syndrome-hypermobility type and gastrointestinal symptoms in university students: a cross-sectional study. Neurogastroenterol Motil 2017;29:e12942.
  • 8. De Wandele I, Calders P, Peersman W, Rimbaut S, De Backer T, Malfait F, et al. Autonomic symptom burden in the hypermobility type of Ehlers-Danlos syndrome: a comparative study with two other EDS types, fibromyalgia, and healthy controls. Semin Arthritis Rheum 2014;44:353-61.
  • 9. Scheper MC, Juul-Kristensen B, Rombaut L, ameckers EA, Verbunt J, Engelbert RH. Disability in adolescents and adults diagnosed with hypermobility-related disorders: a meta-analysis. Arch Phys Med Rehabil 2016;97:2174-87.
  • 10. Scheper MC, Nicholson LL, Adams RD, Tofts L, Pacey V. The natural history of children with joint hypermobility syndrome and Ehlers-Danlos hypermobility type: a longitudinal cohort study. Rheumatology (Oxford) 2017;56:2073-83.
  • 11. Scheper MC, de Vries JE, Juul-Kristensen B, Nollet F, Engelbert RH. The functional consequences of generalized joint hypermobility: a cross-sectional study. BMC Musculoskelet Disord 2014;15:243.
  • 12. Remvig L, Jensen DV, Ward RC. Epidemiology of general joint hypermobility and basis for the proposed criteria for benign joint hypermobility syndrome: review of the literature. J Rheumatol 2007;34:804-9.
  • 13. Remvig L, Flycht L, Christensen KB, Juul-Kristensen B. Lack of consensus on tests and criteria for generalized joint hypermobility, Ehlers-Danlos syndrome: hypermobile type and joint hypermobility syndrome. Am J Med Genet A 2014;164A:591-6.
  • 14. Barçak ÖF, Karkucak M, Capkın E, Karagüzel G, Dilber B, Dedeoğlu DD. Prevalence of generalized joint hypermobility and fibromyalgia syndrome in the children population of Trabzon: a Turkish study. Turk Phys Med Rehab 2015;61:6-11.
  • 15. Ofluoglu D, Gunduz OH, Kul-Panza E, Guven Z. Hypermobility in women with fibromyalgia syndrome. Clin Rheumatol 2006;25:291-3.
  • 16. Seçkin U, Tur BS, Yilmaz O, Yağci I, Bodur H, Arasil T. The prevalence of joint hypermobility among high school students. Rheumatol Int 2005;25:260-3.
  • 17. Yıldırım Y, Yılmaz S, Ayhan E, Saygı S, Yanaral F, Zubarioğlu UA, et al. [The frequency of joint hypermobility in healthy school children]. Türk Pediatri Arşivi. 2005;40:83-6. [Article in Turkish]
  • 18. Juul-Kristensen B, Røgind H, Jensen D, Remvig L. Inter-examiner reproducibility of tests and criteria for generalized joint hypermobility and benign joint hypermobility syndrome. Rheumatology (Oxford) 2007;46:1835-41.
  • 19. Grahame R, Bird H, Child A. The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobility syndrome (BJHS). J Rheumatol 2000;27:1777-9.
  • 20. Castori M, Tinkle B, Levy H, Grahame R, Malfait F, Hakim A. A framework for the classification of joint hypermobility and related conditions. Am J Med Genet C Semin Med Genet 2017;175:148-57.
  • 21. Beighton P, Paepe AD, Steinmann B, Tsipouras P, Wenstrup RJ. Ehlers-Danlos syndromes: revised nosology, Villefranche, 1997. Ehlers-Danlos National Foundation (USA) and Ehlers-Danlos Support Group (UK). Am J Med Genet 1998;77:31-7.
  • 22. Çakmakçı E, Çelik C, Karagöz A, Yücel M. [Hypermobility in the outpatients referred to the physical therapy clinic]. Turk J Phys Med Rehab 1998;1(3). [Article in Turkish]
  • 23. Russek LN, Errico DM. Prevalence, injury rate and, symptom frequency in generalized joint laxity and joint hypermobility syndrome in a “healthy” college population. Clin Rheumatol 2016;35:1029-39.
  • 24. Russek L, Errico D. The prevalence of generalized joint laxity and joint hypermobility syndrome among female college athletes. J Orthop Sports Phys Ther 2013;43:A5.
  • 25. Soper K, Simmonds JV, Kaz Kaz H, Ninis N. The influence of joint hypermobility on functional movement control in an elite netball population: a preliminary cohort study. Phys Ther Sport. 2015;16:127-34.
  • 26. Al-Rawi ZS, Al-Aszawi AJ, Al-Chalabi T. Joint mobility among university students in Iraq. Rheumatology 1985;24:326-31.
  • 27. Kulas Søborg M-L, Leganger J, Quitzau Mortensen L, Rosenberg J, Burcharth J. Establishment and baseline characteristics of a nationwide Danish cohort of patients with Ehlers-Danlos syndrome. Rheumatology (Oxford) 2017;56:763-7.
  • 28. Mishra M, Ryan P, Atkinson P, Taylor H, Bell J, Calver D, et al. Extra-articular features of benign joint hypermobility syndrome. Br J Rheumatol 1996;35:861-6.
  • 29. Hakim AJ, Sahota A. Joint hypermobility and skin elasticity: the hereditary disorders of connective tissue. Clin Dermatol 2006;24:521-33.
  • 30. Albayrak I, Yilmaz H, Akkurt HE, Salli A, Karaca G. Is pain the only symptom in patients with benign joint hypermobility syndrome? Clin Rheumatol 2015;34:1613-9.

Prevalence of joint hypermobility, hypermobility spectrum disorder and hypermobile Ehlers-Danlos syndrome in a university population: an observational study

Yıl 2020, Cilt: 6 Sayı: 2, 120 - 129, 04.03.2020
https://doi.org/10.18621/eurj.466831

Öz

Objectives:
To investigate
the prevalence of joint hypermobility classes, hypermobility spectrum
disorders, hypermobile Ehlers-Danlos syndrome and their relations with sex ina
university population. They are notable topics in rehabilitation, since they
represents the basis for some secondary disability conditions.

Methods: Three hundred and
thirty-five
students met the
inclusion criteria (university students who are not disabled, without known
disease, aged 18-25 years). Joint hypermobility were classified as generalized,
peripheral and localized asymptomatic or hypermobility spectrum disorders.
Hypermobile Ehlers-Danlos syndrome was defined according to; 1) Brighton
criteria with cut-off Beighton scoring ≥ 4/9, 2) Villefranche criteria with
cut-off Beighton scoring ≥ 5/9, and 3) The 2017 International Classification of
Ehlers-Danlos syndrome.

Results: In total, 77.3% (n = 259) of participants had any
class of joint hypermobility and 25.9% (n=87) of them had generalized class.
Asymptomatic joint hypermobility and hypermobility spectrum disorders
prevalence in a university population were found to be 38.8% and 38.5%,
respectively. Generalized, peripheral, localized asymptomatic joint
hypermobility and hypermobility spectrum disorders were found; 13.1%, 4.2%,
21.5%, and 12.8%, 7.5%, 18.2%, respectively. Prevalence of hypermobile
Ehlers-Danlos syndrome according to three classifications were found to be;
19.4%, 15.2%, and 1.2%, respectively.







Conclusions: The most common classes are localized asymptomatic
joint hypermobility in women and localized hypermobility spectrum disorders in
men. Awareness of the prevalence of joint hypermobility, hypermobility spectrum
disorders and hypermobile Ehlers-Danlos syndrome in healthy young population
may contribute prevention of disability. 

Kaynakça

  • 1. Beighton P, Solomon L, Soskolne C. Articular mobility in an African population. Ann Rheum Dis 1973;32:413-8.
  • 2. Simmonds JV, Herbland A, Hakim A, Ninis N, Lever W, Aziz Q, et al. Exercise beliefs and behaviours of individuals with Joint Hypermobility syndrome/Ehlers-Danlos syndrome-hypermobility type. Disabil Rehabil 2019;41:445-55.
  • 3. Krahe AM, Adams RD, Nicholson LL. Features that exacerbate fatigue severity in joint hypermobility syndrome/Ehlers-Danlos syndrome-hypermobility type. Disabil Rehabil 2018;40:1989-96.
  • 4. Malfait F, Francomano C, Byers P, Belmont J, Berglund B, Black J,et al. The 2017 international classification of the Ehlers-Danlos syndromes. Am J Med Genet C Semin Med Genet 2017;175:8-26.
  • 5. Bovet C, Carlson M, Taylor M. Quality of life, unmet needs, and iatrogenic injuries in rehabilitation of patients with Ehlers-Danlos Syndrome hypermobility type/Joint Hypermobility Syndrome. Am J Med Genet A 2016;170:2044-51.
  • 6. Gerwin RD. Benign joint hypermobility is not benign. Myopain 2015;23:11-2.
  • 7. Fikree A, Aktar R, Morris JK, Grahame R, Knowles CH, Aziz Q. The association between Ehlers-Danlos syndrome-hypermobility type and gastrointestinal symptoms in university students: a cross-sectional study. Neurogastroenterol Motil 2017;29:e12942.
  • 8. De Wandele I, Calders P, Peersman W, Rimbaut S, De Backer T, Malfait F, et al. Autonomic symptom burden in the hypermobility type of Ehlers-Danlos syndrome: a comparative study with two other EDS types, fibromyalgia, and healthy controls. Semin Arthritis Rheum 2014;44:353-61.
  • 9. Scheper MC, Juul-Kristensen B, Rombaut L, ameckers EA, Verbunt J, Engelbert RH. Disability in adolescents and adults diagnosed with hypermobility-related disorders: a meta-analysis. Arch Phys Med Rehabil 2016;97:2174-87.
  • 10. Scheper MC, Nicholson LL, Adams RD, Tofts L, Pacey V. The natural history of children with joint hypermobility syndrome and Ehlers-Danlos hypermobility type: a longitudinal cohort study. Rheumatology (Oxford) 2017;56:2073-83.
  • 11. Scheper MC, de Vries JE, Juul-Kristensen B, Nollet F, Engelbert RH. The functional consequences of generalized joint hypermobility: a cross-sectional study. BMC Musculoskelet Disord 2014;15:243.
  • 12. Remvig L, Jensen DV, Ward RC. Epidemiology of general joint hypermobility and basis for the proposed criteria for benign joint hypermobility syndrome: review of the literature. J Rheumatol 2007;34:804-9.
  • 13. Remvig L, Flycht L, Christensen KB, Juul-Kristensen B. Lack of consensus on tests and criteria for generalized joint hypermobility, Ehlers-Danlos syndrome: hypermobile type and joint hypermobility syndrome. Am J Med Genet A 2014;164A:591-6.
  • 14. Barçak ÖF, Karkucak M, Capkın E, Karagüzel G, Dilber B, Dedeoğlu DD. Prevalence of generalized joint hypermobility and fibromyalgia syndrome in the children population of Trabzon: a Turkish study. Turk Phys Med Rehab 2015;61:6-11.
  • 15. Ofluoglu D, Gunduz OH, Kul-Panza E, Guven Z. Hypermobility in women with fibromyalgia syndrome. Clin Rheumatol 2006;25:291-3.
  • 16. Seçkin U, Tur BS, Yilmaz O, Yağci I, Bodur H, Arasil T. The prevalence of joint hypermobility among high school students. Rheumatol Int 2005;25:260-3.
  • 17. Yıldırım Y, Yılmaz S, Ayhan E, Saygı S, Yanaral F, Zubarioğlu UA, et al. [The frequency of joint hypermobility in healthy school children]. Türk Pediatri Arşivi. 2005;40:83-6. [Article in Turkish]
  • 18. Juul-Kristensen B, Røgind H, Jensen D, Remvig L. Inter-examiner reproducibility of tests and criteria for generalized joint hypermobility and benign joint hypermobility syndrome. Rheumatology (Oxford) 2007;46:1835-41.
  • 19. Grahame R, Bird H, Child A. The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobility syndrome (BJHS). J Rheumatol 2000;27:1777-9.
  • 20. Castori M, Tinkle B, Levy H, Grahame R, Malfait F, Hakim A. A framework for the classification of joint hypermobility and related conditions. Am J Med Genet C Semin Med Genet 2017;175:148-57.
  • 21. Beighton P, Paepe AD, Steinmann B, Tsipouras P, Wenstrup RJ. Ehlers-Danlos syndromes: revised nosology, Villefranche, 1997. Ehlers-Danlos National Foundation (USA) and Ehlers-Danlos Support Group (UK). Am J Med Genet 1998;77:31-7.
  • 22. Çakmakçı E, Çelik C, Karagöz A, Yücel M. [Hypermobility in the outpatients referred to the physical therapy clinic]. Turk J Phys Med Rehab 1998;1(3). [Article in Turkish]
  • 23. Russek LN, Errico DM. Prevalence, injury rate and, symptom frequency in generalized joint laxity and joint hypermobility syndrome in a “healthy” college population. Clin Rheumatol 2016;35:1029-39.
  • 24. Russek L, Errico D. The prevalence of generalized joint laxity and joint hypermobility syndrome among female college athletes. J Orthop Sports Phys Ther 2013;43:A5.
  • 25. Soper K, Simmonds JV, Kaz Kaz H, Ninis N. The influence of joint hypermobility on functional movement control in an elite netball population: a preliminary cohort study. Phys Ther Sport. 2015;16:127-34.
  • 26. Al-Rawi ZS, Al-Aszawi AJ, Al-Chalabi T. Joint mobility among university students in Iraq. Rheumatology 1985;24:326-31.
  • 27. Kulas Søborg M-L, Leganger J, Quitzau Mortensen L, Rosenberg J, Burcharth J. Establishment and baseline characteristics of a nationwide Danish cohort of patients with Ehlers-Danlos syndrome. Rheumatology (Oxford) 2017;56:763-7.
  • 28. Mishra M, Ryan P, Atkinson P, Taylor H, Bell J, Calver D, et al. Extra-articular features of benign joint hypermobility syndrome. Br J Rheumatol 1996;35:861-6.
  • 29. Hakim AJ, Sahota A. Joint hypermobility and skin elasticity: the hereditary disorders of connective tissue. Clin Dermatol 2006;24:521-33.
  • 30. Albayrak I, Yilmaz H, Akkurt HE, Salli A, Karaca G. Is pain the only symptom in patients with benign joint hypermobility syndrome? Clin Rheumatol 2015;34:1613-9.
Toplam 30 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Romatoloji ve Artrit, Rehabilitasyon
Bölüm Original Article
Yazarlar

Filiz Tuna 0000-0002-9563-8028

Yayımlanma Tarihi 4 Mart 2020
Gönderilme Tarihi 3 Ekim 2018
Kabul Tarihi 7 Ocak 2019
Yayımlandığı Sayı Yıl 2020 Cilt: 6 Sayı: 2

Kaynak Göster

AMA Tuna F. Prevalence of joint hypermobility, hypermobility spectrum disorder and hypermobile Ehlers-Danlos syndrome in a university population: an observational study. Eur Res J. Mart 2020;6(2):120-129. doi:10.18621/eurj.466831

e-ISSN: 2149-3189 


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