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Yıl 2023, Cilt: 9 Sayı: 6 - November 2023, 1286 - 1292, 04.11.2023
https://doi.org/10.18621/eurj.1241649

Öz

Kaynakça

  • 1. Mason A, Malik A, Ginglen JG. Hypertonic fluids. StatPearls [Internet]. 2021 Jul 11. Available at: https://www.ncbi.nlm.nih.gov/books/NBK542194/#:~:text=Hypertonic%20Saline%3A%20Hypertonic%20saline%20is,increased%20intracranial%20pressure%20(ICP). Accessed February 1, 2022.
  • 2. Mortimer DS, Jancik J. Administering hypertonic saline to patients with severe traumatic brain injury. J Neurosci Nurs 2006;38:142-6.
  • 3. Doyle J, Davis DP, Hoyt DB. The use of hypertonic saline in the treatment of traumatic brain injury. J Trauma 2001;50:367-83.
  • 4. Feig PU, McCurdy DK.The hypertonic state. NEJM 1977;297:1444-54.
  • 5. Hypertonic saline. National Cancer Institute. [Internet]. Available at: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/hypertonic-saline. Accessed February 1, 2022.
  • 6. Metheny NA, Moritz ML. Administration of 3% sodium chloride via a peripheral vein: a literature review. J Infus Nurs 2021;44:94-102.
  • 7. Sokhal N, Rath GP, Chaturvedi A, Singh M, Dash HH. Comparison of 20% mannitol and 3% hypertonic saline on intracranial pressure and systemic hemodynamics. J Clin Neurosci 2017;42:148-54.
  • 8. Johnson AL, Criddle LM. Pass the salt: indications for and implications of using hypertonic saline. Crit Care Nurse 2004;24:36-8.
  • 9. Zhang L, Mendoza‐Sassi RA, Wainwright C, Klassen TP. Nebulised hypertonic saline solution for acute bronchiolitis in infants. Cochrane Database Syst Rev 2017;12(12):CD006458.
  • 10. Wark P, McDonald VM. Nebulised hypertonic saline for cystic fibrosis. Cochrane Database Syst Rev 2018;9(9):CD001506.
  • 11. Leung V, Watson S. Clinical use of topical hypertonic saline eye drops in a quaternary referral eye care centre over 5 years in Sydney, Australia. Clin Experiment Ophthalmol 2018;47:673-5.
  • 12. Marchisio P, Varricchio A, Baggi E, Bianchini S, Capasso ME, Torretta S, et al. Hypertonic saline is more effective than normal saline in seasonal allergic rhinitis in children. Int J Immunopathol 2012;25:721-30.
  • 13. Li CL, Lin HC, Lin CY, Hsu TF. Effectiveness of hypertonic saline nasal irrigation for alleviating allergic rhinitis in children: a systematic review and meta-analysis. J Clin Med 2019;8:64.
  • 14. Shi J, Tan L, Ye J, Hu L. Hypertonic saline and mannitol in patients with traumatic brain injury: a systematic and meta-analysis. Medicine (Baltimore) 2020;99:e21655.
  • 15. Mangat HS, Wu X, Gerber LM, Schwarz JT, Fakhar M, Murthy SB, et al. Hypertonic saline is superior to mannitol for the combined effect on intracranial pressure and cerebral perfusion pressure burdens in patients with severe traumatic brain injury. Neurosurg 2020;86:221-30.
  • 16. Guideline to make up hypertonic saline (3% NaCl). [Internet]. 2021 Jul 11. Available at: https://www.sort.nhs.uk/Media/Guidelines/Hypertonicsaline3sodiumchlorideguideline.pdf. Accessed February 1, 2022.
  • 17. Banks CJ, Furyk JS. Hypertonic saline use in the emergency department. Emerg Med Australas 2008;20:294-305.
  • 18. Sousa Jr LM, de Andrade AF, Belon AR, Soares MS, Amorim RL, Otochi JP, et al. Evaluation of the maintained effect of 3% hypertonic saline solution in an animal model of intracranial hypertension. Med Sci Monit Basic Res 2016;22:123-7.
  • 19. Brenkert TE, Estrada CM, McMorrow SP, Abramo TJ. Intravenous hypertonic saline use in the pediatric emergency department. Pediatr Emerg Care 2013;29:71-3.
  • 20. Ihua B, Nsofor I. Emigration of Nigerian Medical Doctors Survey Report. Technical Report for NOI Polls and Nigeria Health Watch. Abuja, Nigeria. 2017. https://www. researchgate.net/publication/319546512_Emigration_of_Nigerian_Medical_Doctors_Survey_Report. Accessed 21 Jan; 2019.
  • 21. Mirtajani SB, Farnia P, Hassanzad M, Ghanavi J, Farnia P, Velayati AA. Geographical distribution of cystic fibrosis; The past 70 years of data analyzis. Biomed Biotechnol Res J 2017;1:105-12.
  • 22. Shanthosh Kumar S, Nagesh VK, Hunter J, Sange I. A case of severe hyponatremia in a patient with primary adrenal insufficiency. Cureus 2021;13:e17946.
  • 23. Levy LD, Carrion T, Davis K, Mendez M, Martinez K, Johnson G, et al. Sodium bicarbonate as a tool for managing head trauma. JEMS 2017;42(7).

Assessment of the knowledge and use of hypertonic saline among doctors working in paediatrics departments of tertiary institutions in the five states of South-East Nigeria

Yıl 2023, Cilt: 9 Sayı: 6 - November 2023, 1286 - 1292, 04.11.2023
https://doi.org/10.18621/eurj.1241649

Öz

Objectives: This study aimed to evaluate the knowledge and use of hypertonic saline among doctors in the Southeast region of Nigeria.

Methods: It was a cross-sectional study conducted amongst 182 doctors in the paediatric departments of the six tertiary institutions in South Eastern Nigeria. Data to assess knowledge and use of hypertonic saline were collected using self-administered, structured questionnaires.

Results: After aggregating the knowledge questions (definition of hypertonic saline, knowledge of available concentrations and modes of administration) and categorizing knowledge into good or poor, 148 (81.3%) had good knowledge, while 34 (18.7%) had poor knowledge. Respondents who had ever seen an infusion of hypertonic saline were 93 (51.1%), while only 62 (34.1%) had ever used it during their practice. Among those who had used it, only 33 (18.1%) obtained it from their hospital pharmacy. Most respondents (91.2%) would support advocacy for its increased availability and use in Nigeria.

Conclusions: Our study demonstrated good knowledge of hypertonic saline, however, there is low usage due to unavailability. There is a need for collaboration between paediatricians, pharmaceutical companies and other stakeholders to create demand and initiate the production of hypertonic saline.

Kaynakça

  • 1. Mason A, Malik A, Ginglen JG. Hypertonic fluids. StatPearls [Internet]. 2021 Jul 11. Available at: https://www.ncbi.nlm.nih.gov/books/NBK542194/#:~:text=Hypertonic%20Saline%3A%20Hypertonic%20saline%20is,increased%20intracranial%20pressure%20(ICP). Accessed February 1, 2022.
  • 2. Mortimer DS, Jancik J. Administering hypertonic saline to patients with severe traumatic brain injury. J Neurosci Nurs 2006;38:142-6.
  • 3. Doyle J, Davis DP, Hoyt DB. The use of hypertonic saline in the treatment of traumatic brain injury. J Trauma 2001;50:367-83.
  • 4. Feig PU, McCurdy DK.The hypertonic state. NEJM 1977;297:1444-54.
  • 5. Hypertonic saline. National Cancer Institute. [Internet]. Available at: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/hypertonic-saline. Accessed February 1, 2022.
  • 6. Metheny NA, Moritz ML. Administration of 3% sodium chloride via a peripheral vein: a literature review. J Infus Nurs 2021;44:94-102.
  • 7. Sokhal N, Rath GP, Chaturvedi A, Singh M, Dash HH. Comparison of 20% mannitol and 3% hypertonic saline on intracranial pressure and systemic hemodynamics. J Clin Neurosci 2017;42:148-54.
  • 8. Johnson AL, Criddle LM. Pass the salt: indications for and implications of using hypertonic saline. Crit Care Nurse 2004;24:36-8.
  • 9. Zhang L, Mendoza‐Sassi RA, Wainwright C, Klassen TP. Nebulised hypertonic saline solution for acute bronchiolitis in infants. Cochrane Database Syst Rev 2017;12(12):CD006458.
  • 10. Wark P, McDonald VM. Nebulised hypertonic saline for cystic fibrosis. Cochrane Database Syst Rev 2018;9(9):CD001506.
  • 11. Leung V, Watson S. Clinical use of topical hypertonic saline eye drops in a quaternary referral eye care centre over 5 years in Sydney, Australia. Clin Experiment Ophthalmol 2018;47:673-5.
  • 12. Marchisio P, Varricchio A, Baggi E, Bianchini S, Capasso ME, Torretta S, et al. Hypertonic saline is more effective than normal saline in seasonal allergic rhinitis in children. Int J Immunopathol 2012;25:721-30.
  • 13. Li CL, Lin HC, Lin CY, Hsu TF. Effectiveness of hypertonic saline nasal irrigation for alleviating allergic rhinitis in children: a systematic review and meta-analysis. J Clin Med 2019;8:64.
  • 14. Shi J, Tan L, Ye J, Hu L. Hypertonic saline and mannitol in patients with traumatic brain injury: a systematic and meta-analysis. Medicine (Baltimore) 2020;99:e21655.
  • 15. Mangat HS, Wu X, Gerber LM, Schwarz JT, Fakhar M, Murthy SB, et al. Hypertonic saline is superior to mannitol for the combined effect on intracranial pressure and cerebral perfusion pressure burdens in patients with severe traumatic brain injury. Neurosurg 2020;86:221-30.
  • 16. Guideline to make up hypertonic saline (3% NaCl). [Internet]. 2021 Jul 11. Available at: https://www.sort.nhs.uk/Media/Guidelines/Hypertonicsaline3sodiumchlorideguideline.pdf. Accessed February 1, 2022.
  • 17. Banks CJ, Furyk JS. Hypertonic saline use in the emergency department. Emerg Med Australas 2008;20:294-305.
  • 18. Sousa Jr LM, de Andrade AF, Belon AR, Soares MS, Amorim RL, Otochi JP, et al. Evaluation of the maintained effect of 3% hypertonic saline solution in an animal model of intracranial hypertension. Med Sci Monit Basic Res 2016;22:123-7.
  • 19. Brenkert TE, Estrada CM, McMorrow SP, Abramo TJ. Intravenous hypertonic saline use in the pediatric emergency department. Pediatr Emerg Care 2013;29:71-3.
  • 20. Ihua B, Nsofor I. Emigration of Nigerian Medical Doctors Survey Report. Technical Report for NOI Polls and Nigeria Health Watch. Abuja, Nigeria. 2017. https://www. researchgate.net/publication/319546512_Emigration_of_Nigerian_Medical_Doctors_Survey_Report. Accessed 21 Jan; 2019.
  • 21. Mirtajani SB, Farnia P, Hassanzad M, Ghanavi J, Farnia P, Velayati AA. Geographical distribution of cystic fibrosis; The past 70 years of data analyzis. Biomed Biotechnol Res J 2017;1:105-12.
  • 22. Shanthosh Kumar S, Nagesh VK, Hunter J, Sange I. A case of severe hyponatremia in a patient with primary adrenal insufficiency. Cureus 2021;13:e17946.
  • 23. Levy LD, Carrion T, Davis K, Mendez M, Martinez K, Johnson G, et al. Sodium bicarbonate as a tool for managing head trauma. JEMS 2017;42(7).

Ayrıntılar

Birincil Dil İngilizce
Konular Çocuk Sağlığı ve Hastalıkları, Acil Tıp, Yoğun Bakım
Bölüm Original Article
Yazarlar

Ikenna NDU
Department of Paediatrics, Enugu State University Teaching Hospital, Enugu. Enugu State, Nigeria
0000-0003-2198-5614
Nigeria


Benedict EDELU
Department of Paediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu State, Nigeria
0000-0001-9555-5559
Nigeria


Kenechukwu ILOH
Department of Paediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu State, Nigeria
0000-0002-5263-131X
Nigeria


Obinna NDUAGUBAM
Department of Paediatrics, Enugu State University Teaching Hospital, Enugu. Enugu State, Nigeria
0000-0003-3073-8666
Nigeria


Chukwunonso Chıgozıe IHEJI
Department of Paediatrics, Enugu State University Teaching Hospital, Enugu. Enugu State, Nigeria
0000-0002-1902-3769
Nigeria


Chijioke EZEUDU
Department of Paediatrics, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria
0000-0003-3799-4267
Nigeria


Joseph EZEOGU
Department of Paediatrics, Federal University Teaching Hospital, Owerri, Imo State, Nigeria
0000-0001-8034-3756
Nigeria


Obianuju Ojinika IGBOKWE
Department of Paediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu State, Nigeria
0000-0001-7292-2555
Nigeria


Ogochukwu Nneka ILOH
Department of Paediatrics, University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu State, Nigeria
0000-0002-1746-5192
Nigeria


Oluchi Mildred IZUKA
Department of Paediatrics, Federal Medical Centre, Umuahia, Abia State, Nigeria
0000-0002-7966-5173
Nigeria


Linda NWOKEJİ-ONWE
Department of Paediatrics, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi State, Nigeria
0000-0002-6804-5964
Nigeria


Ngozi ONU
Department of Paediatrics, Enugu State University Teaching Hospital, Enugu. Enugu State, Nigeria
0000-0002-4969-3851
Nigeria

Erken Görünüm Tarihi 29 Mayıs 2023
Yayımlanma Tarihi 4 Kasım 2023
Gönderilme Tarihi 25 Ocak 2023
Kabul Tarihi 15 Nisan 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 9 Sayı: 6 - November 2023

Kaynak Göster

AMA
NDU I, EDELU B, ILOH K, NDUAGUBAM O, IHEJI CC, EZEUDU C, EZEOGU J, IGBOKWE OO, ILOH ON, IZUKA OM, NWOKEJİ-ONWE L, ONU N. Assessment of the knowledge and use of hypertonic saline among doctors working in paediatrics departments of tertiary institutions in the five states of South-East Nigeria. Eur Res J. Kasım 2023;9(6):1286-1292. doi:10.18621/eurj.1241649

e-ISSN: 2149-3189 


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