Olgu Sunumu
BibTex RIS Kaynak Göster

Primary pulmonary Ewing sarcoma: a rare case report

Yıl 2024, Cilt: 10 Sayı: 1 - January 2024, 149 - 153, 04.01.2024
https://doi.org/10.18621/eurj.1336479

Öz

Ewing sarcoma (ES) is a malignant soft tissue tumor that consists of undifferentiated neuroectodermal cells. The anatomical sites of ES are commonly the pelvis and long bones. Metastasis is the cause of the most prevalent pulmonary ES. The primary lung origin of ES is extremely uncommon. Here, we report a rare case of primary pulmonary ES diagnosed from cytology and biopsy material. A chest X-ray revealed a lesion with a 9 × 7.5 cm diameter in the pericardiac area of the right lung. Clinical and radiological examinations (computed tomography and positron emission tomography) demonstrated that the lesion was a primary lesion. No distant metastasis was detected. Bronchoscopy-guided fine-needle aspiration and cytological analysis of the lesion revealed uniformly shaped small round cell morphology. Immunohistochemistry performed on the cell block produced positive results for CD99 and FLI-1. These immunohistochemical findings support the ES diagnosis.

Kaynakça

  • 1. Sohn AJ, Lang B, McCarroll M, Agarwal A. Primary pulmonary Ewing sarcoma/peripheral primitive neuroectodermal tumor. Proc (Bayl Univ Med Cent). 2020;33(4):646-648. doi: 10.1080/08998280.2020.1798723.
  • 2. Wu HH, Wingfield-Digby J, Jifon G. Primary Ewing sarcoma of the lung: a challenging case. J R Coll Physicians Edinb. 2020;50(2):141-143. doi: 10.4997/JRCPE.2020.212.
  • 3. Dharmalingam P, Nargund A, MukundaPai M, Patil Okaly GV. Primary Ewing sarcoma of the lung diagnosed on cytology: case report with review of literature. Diagn Cytopathol. 2020;48(11):1098-1101. doi: 10.1002/dc.24458.
  • 4. Hammar S, Bockus D, Remington F, Cooper L. The unusual spectrum of neuroendocrine lung neoplasms. Ultrastruct Pathol. 1989;13(5-6):515-560. doi: 10.3109/01913128909074534.
  • 5. Fan YH, Ma HX, Guo SP, Chen Y, Zhang SP. Application of anlotinib combined with neoadjuvant chemotherapy in primary EWS/PNET of lung: a case report. Front Oncol. 2022;12:822469. doi: 10.3389/fonc.2022.822469.
  • 6. Zhang J, Dong A, Cui Y, Wang Y. FDG PET/CT in a case of primary pulmonary Ewing sarcoma. Clin Nucl Med. 2019;44(8):666-668. doi: 10.1097/RLU.0000000000002659.
  • 7. Öztürk S, Kurtulus Ozturk E, Isiksalan Ozbulbul N, Acu B, Dundar E. Primary Extraosseous Ewing's Sarcoma of the Lung: Radiologic and Pathologic correlation. Cureus. 2021;13(5):e14830. doi: 10.7759/cureus.14830.
  • 8. Mizuguchi K, Minato H, Onishi H, Mitani Y, Kawai J. Cytopathological findings of primary pulmonary Ewing family of tumors with EWSR1 translocation: a case report. Thorac Cancer. 2016;7(5):602-606. doi: 10.1111/1759-7714.12347.
  • 9. Andrew F, Nielsen GP (eds.). Bone and Tissue Pathology: A Volume in the Foundations in Diagnostic Pathology Series. 2nd ed. Elsevier Health Sciences, 2022.
Yıl 2024, Cilt: 10 Sayı: 1 - January 2024, 149 - 153, 04.01.2024
https://doi.org/10.18621/eurj.1336479

Öz

Destekleyen Kurum

YOK

Teşekkür

YOK

Kaynakça

  • 1. Sohn AJ, Lang B, McCarroll M, Agarwal A. Primary pulmonary Ewing sarcoma/peripheral primitive neuroectodermal tumor. Proc (Bayl Univ Med Cent). 2020;33(4):646-648. doi: 10.1080/08998280.2020.1798723.
  • 2. Wu HH, Wingfield-Digby J, Jifon G. Primary Ewing sarcoma of the lung: a challenging case. J R Coll Physicians Edinb. 2020;50(2):141-143. doi: 10.4997/JRCPE.2020.212.
  • 3. Dharmalingam P, Nargund A, MukundaPai M, Patil Okaly GV. Primary Ewing sarcoma of the lung diagnosed on cytology: case report with review of literature. Diagn Cytopathol. 2020;48(11):1098-1101. doi: 10.1002/dc.24458.
  • 4. Hammar S, Bockus D, Remington F, Cooper L. The unusual spectrum of neuroendocrine lung neoplasms. Ultrastruct Pathol. 1989;13(5-6):515-560. doi: 10.3109/01913128909074534.
  • 5. Fan YH, Ma HX, Guo SP, Chen Y, Zhang SP. Application of anlotinib combined with neoadjuvant chemotherapy in primary EWS/PNET of lung: a case report. Front Oncol. 2022;12:822469. doi: 10.3389/fonc.2022.822469.
  • 6. Zhang J, Dong A, Cui Y, Wang Y. FDG PET/CT in a case of primary pulmonary Ewing sarcoma. Clin Nucl Med. 2019;44(8):666-668. doi: 10.1097/RLU.0000000000002659.
  • 7. Öztürk S, Kurtulus Ozturk E, Isiksalan Ozbulbul N, Acu B, Dundar E. Primary Extraosseous Ewing's Sarcoma of the Lung: Radiologic and Pathologic correlation. Cureus. 2021;13(5):e14830. doi: 10.7759/cureus.14830.
  • 8. Mizuguchi K, Minato H, Onishi H, Mitani Y, Kawai J. Cytopathological findings of primary pulmonary Ewing family of tumors with EWSR1 translocation: a case report. Thorac Cancer. 2016;7(5):602-606. doi: 10.1111/1759-7714.12347.
  • 9. Andrew F, Nielsen GP (eds.). Bone and Tissue Pathology: A Volume in the Foundations in Diagnostic Pathology Series. 2nd ed. Elsevier Health Sciences, 2022.

Ayrıntılar

Birincil Dil İngilizce
Konular Patoloji
Bölüm Case Report
Yazarlar

Remzi ARSLAN 0000-0002-3198-4706

Harika Derya TAMER 0009-0000-6016-0039

Ayşe Nur TEMTEK 0009-0001-8434-0541

Erken Görünüm Tarihi 9 Ekim 2023
Yayımlanma Tarihi 4 Ocak 2024
Gönderilme Tarihi 11 Ağustos 2023
Kabul Tarihi 7 Ekim 2023
Yayımlandığı Sayı Yıl 2024 Cilt: 10 Sayı: 1 - January 2024

Kaynak Göster

AMA ARSLAN R, TAMER HD, TEMTEK AN. Primary pulmonary Ewing sarcoma: a rare case report. Eur Res J. Ocak 2024;10(1):149-153. doi:10.18621/eurj.1336479

e-ISSN: 2149-3189 


The European Research Journal, hosted by Turkish JournalPark ACADEMIC, is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

by-nc-nd.png

2024