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The significance of personalized medicine in healthcare services of the 21st century: a brief literature review

Year 2024, Volume: 10 Issue: 6, 626 - 633, 04.11.2024
https://doi.org/10.18621/eurj.1476615

Abstract

In modern healthcare services, patient safety is a primary goal. With technological advancements, the complexity of healthcare services increases, which in turn creates increased pressure on health professionals during decision-making processes and can lead to errors worldwide. Communication gaps, human factors, patient-originated issues, technical failures, and inadequate policies have been identified as the main causes of medical errors. While research shows that errors stem from human nature and are inevitable, it is emphasized that it is possible to develop methods that enhance patient safety. Utilizing digital technologies to improve the quality and efficiency of healthcare services is a crucial strategy. Innovations such as wearable technologies, mobile devices, digital media-delivered education and consulting services, telehealth applications, 3D printers, clinical decision support systems, and implantable biosensors encompass advancements in the digital health field. This research aims to analyze the complex and dynamic structure of healthcare services in the 21st century, especially considering the opportunities presented by the integration of artificial intelligence and genomic data, within the scope of the relevant literature.

References

  • 1. WHO. Patient safety curriculum guide: multi-professional edition. Switzerland. Available at: https://iris.who.int/bitstream/handle/10665/44641/9789241?sequence=3. Accessed 2011.
  • 2. WHO. Patient safety fact file. Patient Safety and Risk Management Service Delivery and Safety. Available at: https://www.who.int/news-room/photo-story/photo-story-detail/10-facts-on-patient-safety. Accessed August 26, 2019.
  • 3. WHO. Cancer. Available at: https://www.who.int/news-room/fact-sheets/detail/cancer. Accessed February 3, 2022.
  • 4. Alemdar DK, Aktaş YY. Medical error types and causes made by nurses in Turkey. TAF Prev Med Bull. 2013;12(3):307-314. doi: 10.5455/pmb.1-1345816200.
  • 5. Blaus A, Madabushi R, Pacanowski M, et al. Personalized Cardiovascular Medicine Today: A Food and Drug Administration/Center for Drug Evaluation and Research Perspective. Circulation. 2015;132(15):1425-32. doi: 10.1161/CIRCULATIONAHA.114.009761.
  • 6. Burau V, Nissen N, Terkildsen MD, Væggemose U. Personalised medicine and the state: A political discourse analysis. Health Policy. 2021;125(1):122-129. doi: 10.1016/j.healthpol.2020.10.005.
  • 7. Carlsten C, Brauer M, Brinkman F, et al. Genes, the environment and personalized medicine: We need to harness both environmental and genetic data to maximize personal and population health. EMBO Rep. 2014;15(7):736-9. doi: 10.15252/embr.201438480.
  • 8. Kasapoğlu A. Türkiye’de sağlık hizmetlerinin dönüşümü. Sosyoloji Araştırmaları Dergisi. 2016;19(2):131-174.
  • 9. Cansever İH, Gökkaya D. Numune hastanelerinden şehir hastanelerine: Türkiye’de hastanelerin dünü, bugünü ve yarını. Balıkesir Sağlık Bilimleri Dergisi. 2023;12(2):425-436. doi: 10.53424/balikesirsbd.1070010.
  • 10. Aksakal Hİ. Dr. Refik saydam önderliğinde Cumhuriyet dönemi sağlık hizmetlerini modernleştirme çabaları. Fırat Üniversitesi Sosyal Bilimler Dergisi. 2017;27(1):219-232.
  • 11. Seçtim H. Sağlikta Dönüşüm Programi Üzerine Bir Değerlendirme. Management and Political Sciences Review. 2019;1(1):117-133.
  • 12. Abubakar AR, Chedi BA, Mohammed KG, Haque M. Drug interaction and its implication in clinical practice and personalized medicine. National Journal of Physiology, Pharmacy and Pharmacology. 2015;5(5):343-349. doi:10.5455/njppp.2015.5.2005201557.
  • 13. Goetz LH, Schork NJ. Personalized medicine: motivation, challenges, and progress. Fertil Steril. 2018;109(6):952-963. doi: 10.1016/j.fertnstert.2018.05.006.
  • 14. Auffray C, Caulfield T, Griffin JL, et al. From genomic medicine to precision medicine: highlights of 2015. Genome Med. 2016;8(1):12. doi: 10.1186/s13073-016-0265-4.
  • 15. Hood L, Rowen L. The Human Genome Project: big science transforms biology and medicine. Genome Med. 2013;5(9):79. doi: 10.1186/gm483.
  • 16. Riley N. Out of date: genetics, history and the British novel of the 1990s. Med Humanit. 2021;47(2):201-209. doi: 10.1136/medhum-2020-012022.
  • 17. Carlsten C, Brauer M, Brinkman F, et al. Genes, the environment and personalized medicine: We need to harness both environmental and genetic data to maximize personal and population health. EMBO Rep. 2014;15(7):736-739. doi: 10.15252/embr.201438480.
  • 18. California State University. The reduction of surgical errors through a development of safety culture, teamwork, and communication. Available at: https://www.proquest.com/docview/860328049/abstract. Accessed 2010.
  • 19. Krzyszczyk P, Acevedo A, Davidoff EJ, et al. The growing role of precision and personalized medicine for cancer treatment. Technology (Singap World Sci). 2018;6(3-4):79-100. doi: 10.1142/S2339547818300020.
  • 20. Lee MS, Flammer AJ, Lerman LO, Lerman A. Personalized medicine in cardiovascular diseases. Korean Circ J. 2012;42(9):583-91. doi: 10.4070/kcj.2012.42.9.583.
  • 21. Banday MZ, Sameer AS, Nissar S. Pathophysiology of diabetes: An overview. Avicenna J Med. 2020;10(4):174-188. doi: 10.4103/ajm.ajm_53_20.
  • 22. Nair SR. Personalized medicine: Striding from genes to medicines. Perspect Clin Res. 2010;1(4):146-50. doi: 10.4103/2229-3485.71775.
  • 23. Ginsburg GS, Willard HF. Genomic and personalized medicine: VI-2. 2nd Edition. US: Academic Press; 2012.
  • 24. Ferreira do Couto ML, Fonseca S, Pozza DH. Pharmacogenetic Approaches in Personalized Medicine for Postoperative Pain Management. Biomedicines. 2024;12(4):729. doi: 10.3390/biomedicines12040729.
  • 25. Kucuksezer UC, Ozdemir C, Akdis M, Akdis CA. Precision/Personalized Medicine in Allergic Diseases and Asthma. Arch Immunol Ther Exp (Warsz). 2018;66(6):431-442. doi: 10.1007/s00005-018-0526-6.
  • 26. Amarasekera M. Immunoglobulin E in health and disease. Asia Pac Allergy. 2011;1(1):12-15. doi: 10.5415/apallergy.2011.1.1.12.
  • 27. Alvaro-Lozano M, Akdis CA, Akdis M, et al. EAACI Allergen Immunotherapy User's Guide. Pediatr Allergy Immunol. 2020;31 Suppl 25(Suppl 25):1-101. doi: 10.1111/pai.13189.
  • 28. Breiteneder H, Peng YQ, Agache I, et al. Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma. Allergy. 2020;75(12):3039-3068. doi: 10.1111/all.14582.
  • 29. Mennella C, Maniscalco U, De Pietro G, Esposito M. Ethical and regulatory challenges of AI technologies in healthcare: A narrative review. Heliyon. 2024;10(4):e26297. doi: 10.1016/j.heliyon.2024.e26297.
  • 30. Stefanicka-Wojtas D, Kurpas D. Personalised Medicine-Implementation to the Healthcare System in Europe (Focus Group Discussions). J Pers Med. 2023;13(3):380. doi: 10.3390/jpm13030380.
  • 31. National Academies (US) Committee on Measuring Economic and Other Returns on Federal Research Investments. Measuring the Impacts of Federal Investments in Research: A Workshop Summary. Washington (DC): National Academies Press (US); 2011. Appendix d, the impact of publicly funded biomedical and health research: a review. Available from: https://www.ncbi.nlm.nih.gov/books/NBK83123/
  • 32. US: Department of Corporate Communications. Joint Commission. Quality and safety, sentinel events statistics released for 2020.; 2021.
  • 33. Jakka S, Rossbach M. An economic perspective on personalized medicine. HUGO J. 2013;7(1):1-6. doi:10.1186/1877-6566-7-1.
  • 34. Jiang F, Jiang Y, Zhi H, et al. Artificial intelligence in healthcare: past, present and future. Stroke Vasc Neurol. 2017;2(4):230-243. doi: 10.1136/svn-2017-000101.
  • 35. Serrano LP, Maita KC, Avila FR, et al. Benefits and Challenges of Remote Patient Monitoring as Perceived by Health Care Practitioners: A Systematic Review. Perm J. 2023;27(4):100-111. doi: 10.7812/TPP/23.022.
  • 36. Kellogg KM, Hettinger Z, Shah M, et al. Our current approach to root cause analysis: is it contributing to our failure to improve patient safety? BMJ Qual Saf. 2017 May;26(5):381-387. doi: 10.1136/bmjqs-2016-005991.
  • 37. Landrigan CP, Parry GJ, Bones CB, Hackbarth AD, Goldmann DA, Sharek PJ. Temporal trends in rates of patient harm resulting from medical care. N Engl J Med. 2010;363(22):2124-34. doi: 10.1056/NEJMsa1004404.
  • 38. Ho D, Quake SR, McCabe ERB, et al. Enabling Technologies for Personalized and Precision Medicine. Trends Biotechnol. 2020;38(5):497-518. doi: 10.1016/j.tibtech.2019.12.021.
  • 39. Lockwood W. Prevention of Medical Errors and Medication Errors Report. 2021. Available at: https://www.rn.org/courses/coursematerial-135.pdf. Accessed 2021.
  • 40. Rodziewicz TL, Houseman B, Vaqar S, et al. Medical Error Reduction and Prevention. [Updated 2024 Feb 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
  • 41. Wampler Muskardin TL, Paredes JL, Appenzeller S, Niewold TB. Lessons from precision medicine in rheumatology. Mult Scler. 2020;26(5):533-539. doi: 10.1177/1352458519884249.
  • 42. Malandrino N, Smith RJ. Personalized medicine in diabetes. Clin Chem. 2011;57(2):231-40. doi: 10.1373/clinchem.2010.156901.
  • 43. Sharma R. Mapping of global, regional and national incidence, mortality and mortality-to-incidence ratio of lung cancer in 2020 and 2050. Int J Clin Oncol. 2022;27(4):665-675. doi: 10.1007/s10147-021-02108-2.
  • 44. Mathur S, Sutton J. Personalized medicine could transform healthcare. Biomed Rep. 2017;7(1):3-5. doi: 10.3892/br.2017.922.
  • 45. Liao J, Li X, Gan Y, Han S, Rong P, Wang W, Li W, Zhou L. Artificial intelligence assists precision medicine in cancer treatment. Front Oncol. 2023;12:998222. doi: 10.3389/fonc.2022.
  • 46. Brown JC, Gerhardt TE, Kwon E. Risk Factors for Coronary Artery Disease. [Updated 2023 Jan 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.
  • 47. Sims TJ, Boye KS, Robinson S, Kennedy-Martin T. Treatment-Related Attributes of Diabetes Therapies and How People with Type 2 Diabetes Report Their Impact on Indicators of Medication-Taking Behaviors. Patient Prefer Adherence. 2022;16:1919-1939. doi: 10.2147/PPA.S367046.
  • 48. Esplin ED, Oei L, Snyder MP. Personalized sequencing and the future of medicine: discovery, diagnosis and defeat of disease. Pharmacogenomics. 2014;15(14):1771-1790. doi: 10.2217/pgs.14.117.
  • 49. Mathur S, Sutton J. Personalized medicine could transform healthcare. Biomed Rep. 2017;7(1):3-5. doi: 10.3892/br.2017.922.
  • 50. Brennan F, Lohman D, Gwyther L. Access to Pain Management as a Human Right. Am J Public Health. 2019;109(1):61-65. doi: 10.2105/AJPH.2018.304743.
  • 51. Mosley SA, Hicks JK, Portman DG, et al. Design and rational for the precision medicine guided treatment for cancer pain pragmatic clinical trial. Contemp Clin Trials. 2018;68:7-13. doi: 10.1016/j.cct.2018.03.001.
  • 52. McGhee SA. How the practice of allergy shows the promise and challenge of personalized medicine. Mol Genet Metab. 2011;104(1-2):3-6. doi: 10.1016/j.ymgme.2011.07.017.
  • 53. Meiliana A, Dewi NM, Wijaya A. Personalized medicine: the future of health care. Indones Biomed J. 2016;8(3):127-146. doi:10.18585/inabj.v8i3.271.
  • 54. Patel CJ, Sivadas A, Tabassum R, Preeprem T, Zhao J, Arafat D, Chen R, Morgan AA, Martin GS, Brigham KL, Butte AJ, Gibson G. Whole genome sequencing in support of wellness and health maintenance. Genome Med. 2013;5(6):58. doi: 10.1186/gm462.
  • 55. Redekop WK, Mladsi D. The faces of personalized medicine: a framework for understanding its meaning and scope. Value Health. 2013;16(6 Suppl):S4-9. doi: 10.1016/j.jval.2013.06.005.
  • 56. Soydemir D, Seren Intepeler S, Mert H. Barriers to Medical Error Reporting for Physicians and Nurses. West J Nurs Res. 2017;39(10):1348-1363. doi: 10.1177/0193945916671934.
  • 57. van Weel C, Kidd MR. Why strengthening primary health care is essential to achieving universal health coverage. CMAJ. 2018;190(15):E463-E466. doi: 10.1503/cmaj.170784.
  • 58. Dayıoğlu N. Assessing the Health-economic Crisis: The Case of Turkey. Lectio Socialis. 2022;6(2):67-80. doi: 10.47478/lectio.1079624
Year 2024, Volume: 10 Issue: 6, 626 - 633, 04.11.2024
https://doi.org/10.18621/eurj.1476615

Abstract

References

  • 1. WHO. Patient safety curriculum guide: multi-professional edition. Switzerland. Available at: https://iris.who.int/bitstream/handle/10665/44641/9789241?sequence=3. Accessed 2011.
  • 2. WHO. Patient safety fact file. Patient Safety and Risk Management Service Delivery and Safety. Available at: https://www.who.int/news-room/photo-story/photo-story-detail/10-facts-on-patient-safety. Accessed August 26, 2019.
  • 3. WHO. Cancer. Available at: https://www.who.int/news-room/fact-sheets/detail/cancer. Accessed February 3, 2022.
  • 4. Alemdar DK, Aktaş YY. Medical error types and causes made by nurses in Turkey. TAF Prev Med Bull. 2013;12(3):307-314. doi: 10.5455/pmb.1-1345816200.
  • 5. Blaus A, Madabushi R, Pacanowski M, et al. Personalized Cardiovascular Medicine Today: A Food and Drug Administration/Center for Drug Evaluation and Research Perspective. Circulation. 2015;132(15):1425-32. doi: 10.1161/CIRCULATIONAHA.114.009761.
  • 6. Burau V, Nissen N, Terkildsen MD, Væggemose U. Personalised medicine and the state: A political discourse analysis. Health Policy. 2021;125(1):122-129. doi: 10.1016/j.healthpol.2020.10.005.
  • 7. Carlsten C, Brauer M, Brinkman F, et al. Genes, the environment and personalized medicine: We need to harness both environmental and genetic data to maximize personal and population health. EMBO Rep. 2014;15(7):736-9. doi: 10.15252/embr.201438480.
  • 8. Kasapoğlu A. Türkiye’de sağlık hizmetlerinin dönüşümü. Sosyoloji Araştırmaları Dergisi. 2016;19(2):131-174.
  • 9. Cansever İH, Gökkaya D. Numune hastanelerinden şehir hastanelerine: Türkiye’de hastanelerin dünü, bugünü ve yarını. Balıkesir Sağlık Bilimleri Dergisi. 2023;12(2):425-436. doi: 10.53424/balikesirsbd.1070010.
  • 10. Aksakal Hİ. Dr. Refik saydam önderliğinde Cumhuriyet dönemi sağlık hizmetlerini modernleştirme çabaları. Fırat Üniversitesi Sosyal Bilimler Dergisi. 2017;27(1):219-232.
  • 11. Seçtim H. Sağlikta Dönüşüm Programi Üzerine Bir Değerlendirme. Management and Political Sciences Review. 2019;1(1):117-133.
  • 12. Abubakar AR, Chedi BA, Mohammed KG, Haque M. Drug interaction and its implication in clinical practice and personalized medicine. National Journal of Physiology, Pharmacy and Pharmacology. 2015;5(5):343-349. doi:10.5455/njppp.2015.5.2005201557.
  • 13. Goetz LH, Schork NJ. Personalized medicine: motivation, challenges, and progress. Fertil Steril. 2018;109(6):952-963. doi: 10.1016/j.fertnstert.2018.05.006.
  • 14. Auffray C, Caulfield T, Griffin JL, et al. From genomic medicine to precision medicine: highlights of 2015. Genome Med. 2016;8(1):12. doi: 10.1186/s13073-016-0265-4.
  • 15. Hood L, Rowen L. The Human Genome Project: big science transforms biology and medicine. Genome Med. 2013;5(9):79. doi: 10.1186/gm483.
  • 16. Riley N. Out of date: genetics, history and the British novel of the 1990s. Med Humanit. 2021;47(2):201-209. doi: 10.1136/medhum-2020-012022.
  • 17. Carlsten C, Brauer M, Brinkman F, et al. Genes, the environment and personalized medicine: We need to harness both environmental and genetic data to maximize personal and population health. EMBO Rep. 2014;15(7):736-739. doi: 10.15252/embr.201438480.
  • 18. California State University. The reduction of surgical errors through a development of safety culture, teamwork, and communication. Available at: https://www.proquest.com/docview/860328049/abstract. Accessed 2010.
  • 19. Krzyszczyk P, Acevedo A, Davidoff EJ, et al. The growing role of precision and personalized medicine for cancer treatment. Technology (Singap World Sci). 2018;6(3-4):79-100. doi: 10.1142/S2339547818300020.
  • 20. Lee MS, Flammer AJ, Lerman LO, Lerman A. Personalized medicine in cardiovascular diseases. Korean Circ J. 2012;42(9):583-91. doi: 10.4070/kcj.2012.42.9.583.
  • 21. Banday MZ, Sameer AS, Nissar S. Pathophysiology of diabetes: An overview. Avicenna J Med. 2020;10(4):174-188. doi: 10.4103/ajm.ajm_53_20.
  • 22. Nair SR. Personalized medicine: Striding from genes to medicines. Perspect Clin Res. 2010;1(4):146-50. doi: 10.4103/2229-3485.71775.
  • 23. Ginsburg GS, Willard HF. Genomic and personalized medicine: VI-2. 2nd Edition. US: Academic Press; 2012.
  • 24. Ferreira do Couto ML, Fonseca S, Pozza DH. Pharmacogenetic Approaches in Personalized Medicine for Postoperative Pain Management. Biomedicines. 2024;12(4):729. doi: 10.3390/biomedicines12040729.
  • 25. Kucuksezer UC, Ozdemir C, Akdis M, Akdis CA. Precision/Personalized Medicine in Allergic Diseases and Asthma. Arch Immunol Ther Exp (Warsz). 2018;66(6):431-442. doi: 10.1007/s00005-018-0526-6.
  • 26. Amarasekera M. Immunoglobulin E in health and disease. Asia Pac Allergy. 2011;1(1):12-15. doi: 10.5415/apallergy.2011.1.1.12.
  • 27. Alvaro-Lozano M, Akdis CA, Akdis M, et al. EAACI Allergen Immunotherapy User's Guide. Pediatr Allergy Immunol. 2020;31 Suppl 25(Suppl 25):1-101. doi: 10.1111/pai.13189.
  • 28. Breiteneder H, Peng YQ, Agache I, et al. Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma. Allergy. 2020;75(12):3039-3068. doi: 10.1111/all.14582.
  • 29. Mennella C, Maniscalco U, De Pietro G, Esposito M. Ethical and regulatory challenges of AI technologies in healthcare: A narrative review. Heliyon. 2024;10(4):e26297. doi: 10.1016/j.heliyon.2024.e26297.
  • 30. Stefanicka-Wojtas D, Kurpas D. Personalised Medicine-Implementation to the Healthcare System in Europe (Focus Group Discussions). J Pers Med. 2023;13(3):380. doi: 10.3390/jpm13030380.
  • 31. National Academies (US) Committee on Measuring Economic and Other Returns on Federal Research Investments. Measuring the Impacts of Federal Investments in Research: A Workshop Summary. Washington (DC): National Academies Press (US); 2011. Appendix d, the impact of publicly funded biomedical and health research: a review. Available from: https://www.ncbi.nlm.nih.gov/books/NBK83123/
  • 32. US: Department of Corporate Communications. Joint Commission. Quality and safety, sentinel events statistics released for 2020.; 2021.
  • 33. Jakka S, Rossbach M. An economic perspective on personalized medicine. HUGO J. 2013;7(1):1-6. doi:10.1186/1877-6566-7-1.
  • 34. Jiang F, Jiang Y, Zhi H, et al. Artificial intelligence in healthcare: past, present and future. Stroke Vasc Neurol. 2017;2(4):230-243. doi: 10.1136/svn-2017-000101.
  • 35. Serrano LP, Maita KC, Avila FR, et al. Benefits and Challenges of Remote Patient Monitoring as Perceived by Health Care Practitioners: A Systematic Review. Perm J. 2023;27(4):100-111. doi: 10.7812/TPP/23.022.
  • 36. Kellogg KM, Hettinger Z, Shah M, et al. Our current approach to root cause analysis: is it contributing to our failure to improve patient safety? BMJ Qual Saf. 2017 May;26(5):381-387. doi: 10.1136/bmjqs-2016-005991.
  • 37. Landrigan CP, Parry GJ, Bones CB, Hackbarth AD, Goldmann DA, Sharek PJ. Temporal trends in rates of patient harm resulting from medical care. N Engl J Med. 2010;363(22):2124-34. doi: 10.1056/NEJMsa1004404.
  • 38. Ho D, Quake SR, McCabe ERB, et al. Enabling Technologies for Personalized and Precision Medicine. Trends Biotechnol. 2020;38(5):497-518. doi: 10.1016/j.tibtech.2019.12.021.
  • 39. Lockwood W. Prevention of Medical Errors and Medication Errors Report. 2021. Available at: https://www.rn.org/courses/coursematerial-135.pdf. Accessed 2021.
  • 40. Rodziewicz TL, Houseman B, Vaqar S, et al. Medical Error Reduction and Prevention. [Updated 2024 Feb 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
  • 41. Wampler Muskardin TL, Paredes JL, Appenzeller S, Niewold TB. Lessons from precision medicine in rheumatology. Mult Scler. 2020;26(5):533-539. doi: 10.1177/1352458519884249.
  • 42. Malandrino N, Smith RJ. Personalized medicine in diabetes. Clin Chem. 2011;57(2):231-40. doi: 10.1373/clinchem.2010.156901.
  • 43. Sharma R. Mapping of global, regional and national incidence, mortality and mortality-to-incidence ratio of lung cancer in 2020 and 2050. Int J Clin Oncol. 2022;27(4):665-675. doi: 10.1007/s10147-021-02108-2.
  • 44. Mathur S, Sutton J. Personalized medicine could transform healthcare. Biomed Rep. 2017;7(1):3-5. doi: 10.3892/br.2017.922.
  • 45. Liao J, Li X, Gan Y, Han S, Rong P, Wang W, Li W, Zhou L. Artificial intelligence assists precision medicine in cancer treatment. Front Oncol. 2023;12:998222. doi: 10.3389/fonc.2022.
  • 46. Brown JC, Gerhardt TE, Kwon E. Risk Factors for Coronary Artery Disease. [Updated 2023 Jan 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.
  • 47. Sims TJ, Boye KS, Robinson S, Kennedy-Martin T. Treatment-Related Attributes of Diabetes Therapies and How People with Type 2 Diabetes Report Their Impact on Indicators of Medication-Taking Behaviors. Patient Prefer Adherence. 2022;16:1919-1939. doi: 10.2147/PPA.S367046.
  • 48. Esplin ED, Oei L, Snyder MP. Personalized sequencing and the future of medicine: discovery, diagnosis and defeat of disease. Pharmacogenomics. 2014;15(14):1771-1790. doi: 10.2217/pgs.14.117.
  • 49. Mathur S, Sutton J. Personalized medicine could transform healthcare. Biomed Rep. 2017;7(1):3-5. doi: 10.3892/br.2017.922.
  • 50. Brennan F, Lohman D, Gwyther L. Access to Pain Management as a Human Right. Am J Public Health. 2019;109(1):61-65. doi: 10.2105/AJPH.2018.304743.
  • 51. Mosley SA, Hicks JK, Portman DG, et al. Design and rational for the precision medicine guided treatment for cancer pain pragmatic clinical trial. Contemp Clin Trials. 2018;68:7-13. doi: 10.1016/j.cct.2018.03.001.
  • 52. McGhee SA. How the practice of allergy shows the promise and challenge of personalized medicine. Mol Genet Metab. 2011;104(1-2):3-6. doi: 10.1016/j.ymgme.2011.07.017.
  • 53. Meiliana A, Dewi NM, Wijaya A. Personalized medicine: the future of health care. Indones Biomed J. 2016;8(3):127-146. doi:10.18585/inabj.v8i3.271.
  • 54. Patel CJ, Sivadas A, Tabassum R, Preeprem T, Zhao J, Arafat D, Chen R, Morgan AA, Martin GS, Brigham KL, Butte AJ, Gibson G. Whole genome sequencing in support of wellness and health maintenance. Genome Med. 2013;5(6):58. doi: 10.1186/gm462.
  • 55. Redekop WK, Mladsi D. The faces of personalized medicine: a framework for understanding its meaning and scope. Value Health. 2013;16(6 Suppl):S4-9. doi: 10.1016/j.jval.2013.06.005.
  • 56. Soydemir D, Seren Intepeler S, Mert H. Barriers to Medical Error Reporting for Physicians and Nurses. West J Nurs Res. 2017;39(10):1348-1363. doi: 10.1177/0193945916671934.
  • 57. van Weel C, Kidd MR. Why strengthening primary health care is essential to achieving universal health coverage. CMAJ. 2018;190(15):E463-E466. doi: 10.1503/cmaj.170784.
  • 58. Dayıoğlu N. Assessing the Health-economic Crisis: The Case of Turkey. Lectio Socialis. 2022;6(2):67-80. doi: 10.47478/lectio.1079624
There are 58 citations in total.

Details

Primary Language English
Subjects Clinical Sciences (Other)
Journal Section Reviews
Authors

Ebru Uğraş Tiryaki 0000-0002-5618-5265

Early Pub Date July 16, 2024
Publication Date November 4, 2024
Submission Date May 1, 2024
Acceptance Date June 23, 2024
Published in Issue Year 2024 Volume: 10 Issue: 6

Cite

AMA Uğraş Tiryaki E. The significance of personalized medicine in healthcare services of the 21st century: a brief literature review. Eur Res J. November 2024;10(6):626-633. doi:10.18621/eurj.1476615

e-ISSN: 2149-3189 


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