Impact of COVID-19 “Stay at home!” Restrictions on the Prevalence of Deep Vein Thrombosis in the Geriatric Population: A Retrospective Controlled Study

Year 2022, , 44 - 48, 22.08.2022

Gülseren Dost Sürücü , Dilay Eken Gedik

https://doi.org/10.26650/experimed.1062664

Abstract

Objective: The restrictions during the coronavirus disease 2019 (COVID-19) pandemic period may have caused an increase in the incidence of deep vein thrombosis (DVT) in the elderly population. We aimed to evaluate whether the frequency of DVT increased in the geriatric population due to the restrictions of COVID-19 pandemic period and to emphasize the importance of exercise in this population.

Materials and Methods: Patients over the age of 65 who applied to our hospital, who underwent lower extremity venous doppler ultrasonography in the last year before the pandemic and in the first year with pandemic restrictions, were retrospectively analyzed from the database. The records of a total of 1531 patients were scanned. Patients with DVT were recorded.

Results: Forty-nine DVT cases in the last year before the pandemic, and 53 DVT cases in the first year of the restrictions were detected. The incidence of DVT in the elderly was found to be higher in the restrictions period.

Conclusion: Although the “Stay at home!” restrictions reduced the rate of spread of the disease, it may also have prepared the ground for serious conditions such as DVT in this population. Home exercise programs are important especially for the elderly population during the pandemic period.

Keywords

Covid-19, Geriatrics, Deep Vein Thrombosis, Exercise, Stay at Home

References

• 1. Segal JB, Eng J, Tamariz LJ, Bass EB. Review of the Evidence on Di-agnosis of Deep Venous Thrombosis and Pulmonary Embolism. Ann Fam Med 2007; 5(1): 63-73. [CrossRef] google scholar
• 2. Ogonda L, Hill J, Doran E, Dennison J, Stevenson M, Beverland D. Aspirin for thromboprophylaxis after primary lower limb arthro-plasty: early thromboembolic events and 90-day mortality in 11,459 patients. Bone Joint J 2016; 98(3): 341-8. [CrossRef] google scholar
• 3. Anderson FA, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, et al. A population based perspective of the hos-pital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med 1991; 151(5): 933-8. [CrossRef] google scholar
• 4. Caprini JA, Arcelus JI, Reyna JJ. Effective risk stratification of surgi-cal and nonsurgical patients for venous thromboembolic disease. Semin Hematol 2001; 3(2): 12-9. [CrossRef] google scholar
• 5. Warlow C, Ogston D, Douglas AS. Venous thrombosis following strokes. Lancet 1972; 299(776)4: 1305-6. [CrossRef] google scholar
• 6. Samama MM. Epidemiology of risk factors of deep venous throm-bosis (DVT) of the lower limbs in community practice: the SIRIUS study. Thromb Haemost 1993; 69: 763. google scholar
• 7. Heit JA, Silverstein MD, Mohr DN, Petterson TM, O'Fallon WM, Melton LJ 3rd. Risk factors for deep vein thrombosis and pulmo-nary embolism: A population-based case-control study. Arch In-tern Med 2000; 160(6): 809-15. [CrossRef] google scholar
• 8. Rahr HB, Sorensen JV. Venous thromboembolism and cancer. Blood Coagul Fibrinolysis 1992; 3(4): 451-60. [CrossRef] google scholar
• 9. Pomp ER, Rosendaal FR, Doggen CJ. Smoking increases the risk of venous thrombosis and acts synergistically with oral contracep-tive use. Am J Hematol 2008; 83(2): 97-102. [CrossRef] google scholar
• 10. Markowitz J. Virtual treatment and social distancing. The Lancet Psychiatry 2020; 7(5): 388-9. [CrossRef] google scholar
• 11. Guan H, Okely AD, Aguilar-Farias N, del Pozo Cruz B, Draper CE, El Hamdouchi A, et al. Promoting healthy movement behaviours among children during the COVID-19 pandemic. Lancet Child Ad-olesc Health 2020; 4(6): 416-8. [CrossRef] google scholar
• 12. Sun F, Norman IJ, While AE. Physical activity in older people: a sys-tematic review. BMC Public Health 2013; 13: 449. [CrossRef] google scholar
• 13. Lautenschlager NT, Almeida OP, Flicker L, Janca A. Can physical activity improve the mental health of older adults? Ann Gen Hosp Psychiatry 2004;3(1):1-5. [CrossRef] google scholar
• 14. Gomes M, Figueiredo D, Teixeira L, Poveda V, Paul C, Santos-Silva A, et al. Physical inactivity among older adults across Europe based on the SHARE database. Age Ageing 2017; 46(1): 71-7. [CrossRef] google scholar
• 15. Guralnik JM, Ferrucci L, Simonsick EM, Salive ME, Wallace RB. Low-er-extremity function in persons over the age of 70 years as a pre-dictor of subsequent disability. N Engl J Med 1995; 332(9): 556-61. [CrossRef] google scholar
• 16. Hirvensalo M, Rantanen T, Heikkinen E. Mobility difficulties and physical activity as predictors of mortality and loss of indepen-dence in the community-living older population. J Am Geriatr Soc 2000; 48(5): 493-8. [CrossRef] google scholar
• 17. Brooks SK, Webster RK, Smith LE, Woodland L, Wessely S, Green-berg N, et al. The psychological impact of quarantine and how to reduce it: rapid review of the evidence. Lancet 2020; 395(10227): 912-20. [CrossRef] google scholar
• 18. Coronavirus disease 2019 (COVID-19)-Situation report, 72. World Health Organization 2020 (Available from: https://apps.who.int/ iris/handle/10665/331685). google scholar
• 19. Bortz II WM. The disuse syndrome. West J Med 1984; 141(5): 691-4. google scholar
• 20. Maugeri G, Castrogiovanni P, Battaglia G, Pippi R, D'Agata V, Palma A, et al. The impact of physical activity on psychological health during Covid-19 pandemic in Italy. Heliyon 2020; 6(6): e04315. [CrossRef] google scholar
• 21. Romeo J, Warnberg J, Pozo T, Marcos A. Physical activity, immunity and infection. Proc Nutr Soc 2010; 69(3): 390-9. [CrossRef] google scholar
• 22. Wu N, Bredin SS, Guan Y, et al. Cardiovascular health benefits of ex-ercise training in persons living with type 1 diabetes: a systematic review and meta-analysis. J Clin Med 2019; 8(2): 253. [CrossRef] google scholar
• 23. Whitfield GP, Carlson SA, Ussery EN, Fulton JE, Galuska DA, Peters-en R. Trends in meeting physical activity guidelines among urban and rural dwelling adults-United States, 2008-2017. MMWR Morb Mortal Wkly Rep 2019; 68(23): 513-8. [CrossRef] google scholar
• 24. Naguib MM, Ellström P, Jarhult JD, Lundkvist Â, Olsen B. Towards pandemic preparedness beyond COVID-19. Lancet Microbe 2020; 1(5): 185-6. [CrossRef] google scholar
• 25. Blum E, Abdelwahed YS, Spiess E, Mueller-Werdan U, Leistner DM, Rosada A. COVID-19 #StayAtHome Restrictions and Deep Vein Thrombosis: Case Report. Interact J Med Res 2021; 10(1): e23443. [CrossRef] google scholar
• 26. Goethals L, Barth N, Guyot J, Hupin D, Celarier T, Bongue B. Impact of Home Quarantine on Physical Activity Among Older Adults Living at Home During the COVID-19 Pandemic: Qualitative Inter-view Study. JMIR Aging 2020; 3(1): e19007. [CrossRef] google scholar
• 27 Parmet WE, Sinha MS Covid-19-The Law and Limits of Quarantine N Engl J Med 2020; 382(15): e28 [CrossRef] google scholar
• 28 Bachireddy C, Chen C, Dar M Securing the Safety Net and Pro-tecting Public Health During a Pandemic: Medicaid's Response to COVID-19 JAMA 2020; 323(20): 2009-10 [CrossRef] google scholar
• 29 Inglesby TV Public Health Measures and the Reproduction Num-ber of SARS-CoV-2 JAMA 2020; 323(21): 2186-7 [CrossRef] google scholar
• 30 World Health Organization Global recommendations on physi-cal activity for health World Health Organization 2010 (Available from: https://apps who int/iris/handle/10665/44399) google scholar
• 31 Cox C, Kamal R, McDermott D How have healthcare utilization and spending changed so far during the coronavirus pandem-ic? San Francisco (CA): Peterson-KFF Health System Tracker; 2020 (Available from: https://www healthsystemtracker org/chart-col-lection/how-have-healthcare-utilization-and-spending-changed-so-far-during-the-coronavirus-pandemic/ google scholar
• 32 . De Rosa S, Spaccarotella C, Basso C, Calabro MP, Curcio A, Filardi PP, et al Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era Eur Heart J 2020; 41(22): 2083-8 [CrossRef] google scholar
• 33 Siegler JE, Heslin ME, Thau L, Smith A, Jovin TG Falling stroke rates during COVID-19 pandemic at a comprehensive stroke center J Stroke Cerebrovasc Dis 2020; 29(8): 104953 [CrossRef] google scholar
• 34 . Helgeland J,Telle KE, Gr0sland M, Huseby BM, Hâberg S, Lindman AS. Admissions to Norwegian hospitals during the COVID-19 pan-demic. Scand J Public Health 2021; 49(7): 681-88. [CrossRef] google scholar