Effect of metallic nanoparticles on cancer cell lines: A review on plant-based biosynthesis

Abstract

The green synthesis method is an environmentally friendly, cost-efficient, and safe method for the production of metallic nanoparticles (MNPs). This method mainly relies on the use of plants and microorganisms as well. While plant-based MNPs are produced via the green synthesis method, the secondary metabolites of plants have the ability to enrich some functional properties of these MNPs. As a result of this, plant-based MNPs can be cytotoxic to some cancer cell lines. This review regarding the effect of plant-based MNPs anticancer activities on various cancer cell lines provides a summary of research articles in this area. Additionally, this review reports secondary metabolites of the plants used to synthesize MNPs. Thus, this article provides an overview of which plant species are being used and which metallic nanoparticles are being studied for anti-cancer activities on which cancer cell lines. This review aims to provide a general perspective for researchers in the field to study novel combinations of plants, metals, and cancer types.

Keywords

• Anti-cancer
• anti-proliferation
• cell line
• green synthesis
• nanoparticles
• metal

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