The relationship between thyroglobulin (Tg) levels and distant metastases before radioiodine (RAI) treatment in differentiated thyroid carcinomas

Yıl 2012, Cilt: 18 Sayı: 1, 11 - 13, 01.02.2012

Ebuzer Kalender Yusuf Zeki Çelen Umut Elboğa Hasan Deniz Demir Hüseyin Karaoğlan Mustafa Yılmaz

Öz

The aim of our study is to determine the relationship between distant metastases and thyroglobulin (Tg) levels measured before radioiodine (RAI) treatment in differentiated thyroid carcinomas. Sixty seven patients with near total or total thyroidectomy were included in the study. Fifty patients did not have lymph node or distant metastases (Group 1), and 17 patients had distant metastases (Group 2). Tg and anti-Tg levels of these patients were measured before RAI treatment when TSH>30 mU/l. Serum Tg levels were found 8,5±10,6 ng/ml and 307±142 ng/ml in Group 1 and Group 2, respectively. There was a significant difference between the mean Tg levels of Group 1 and 2 (p

Anahtar Kelimeler

Thyroglobulin, Neoplasm Metastasis, Thyroid Neoplasms

Diferansiye tiroid karsinomlu hastalarda radyoaktif iyot (RAI) tedavi öncesi tiroglobulin (Tg) düzeylerinin uzak metastazlarla ilişkisi

Öz

Çalışmamızın amacı diferansiye tiroid karsinomlarında radyoaktif iyot (RAI) tedavisi öncesi bakılan tiroglobulin (Tg) değerleri ile uzak metastazlar arasındaki ilişkiyi ortaya koymaktır. Çalışmaya total veya totale yakın tiroidektomi geçirmiş 67 diferansiye tiroid karsinomlu hasta dahil edildi. Hastaların 50'sinde lenf nodu ya da uzak metastazı yoktu (Grup 1), 17'sinde ise uzak metastaz mevcuttu (Grup 2). RAI tedavisi öncesinde TSH>30 mU/l iken tüm hastaların anti-Tg ve Tg düzeylerine bakıldı. Serum Tg değerleri Grup 1'de 8,5±10,6 ng/ml, Grup 2'de 307±142 ng/ml olarak bulundu. Grup 1 ve Grup 2'nin Tg ortalamaları arasındaki farkın anlamlı olduğu görüldü (p

Anahtar Kelimeler

Tiroglobulin, Neoplazm metastazı, Tiroid neoplazmları

Kaynakça

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