<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="research-article"        dtd-version="1.4">
            <front>

                <journal-meta>
                                                                <journal-id>gummfd</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">1300-1884</issn>
                                        <issn pub-type="epub">1304-4915</issn>
                                                                                            <publisher>
                    <publisher-name>Gazi Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.17341/gazimmfd.1631531</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Deep Learning</subject>
                                                            <subject>Neural Networks</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Derin Öğrenme</subject>
                                                            <subject>Nöral Ağlar</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                                                            <article-title>Aktivasyon fonksiyonları ve derin öğrenme mimarilerinin beyin MRI görüntüleri üzerindeki sınıflandırma performanslarının incelenmesi</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-2029-0856</contrib-id>
                                                                <name>
                                    <surname>Özkan</surname>
                                    <given-names>Yasin</given-names>
                                </name>
                                                                    <aff>ZONGULDAK BÜLENT ECEVİT ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20260331">
                    <day>03</day>
                    <month>31</month>
                    <year>2026</year>
                </pub-date>
                                        <volume>41</volume>
                                        <issue>1</issue>
                                        <fpage>519</fpage>
                                        <lpage>532</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20250202">
                        <day>02</day>
                        <month>02</month>
                        <year>2025</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20260116">
                        <day>01</day>
                        <month>16</month>
                        <year>2026</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1986, Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi</copyright-statement>
                    <copyright-year>1986</copyright-year>
                    <copyright-holder>Gazi Üniversitesi Mühendislik Mimarlık Fakültesi Dergisi</copyright-holder>
                </permissions>
            
                                                                                                                        <abstract><p>Beyin tümörü tespiti, tıbbi görüntüleme alanında en kritik süreçlerden biri olup, manyetik rezonans görüntüleme (MRI) yüksek çözünürlüklü yumuşak doku detayları sayesinde tanı sürecinde önemli bir rol oynamaktadır. Ancak MRI görüntülerinin manuel olarak değerlendirilmesi zaman alıcı ve hataya açık bir süreçtir. Bu nedenle, derin öğrenme tabanlı otomatik sistemlerin geliştirilmesi, tanı hızını artırmak ve sağlık hizmetlerinin etkinliğini yükseltmek açısından büyük önem taşımaktadır. Bu çalışmada, Brain MRI görüntülerinden oluşan bir veri seti kullanılarak beyin tümörlerinin sınıflandırılması amaçlanmıştır. Öncelikle, veri setine görüntü işleme teknikleri uygulanarak iyileştirilmiş görüntüler elde edilmiştir. Ardından, orijinal ve iyileştirilmiş görüntüler yedi farklı transfer öğrenme mimarisine girdi olarak verilmiştir. Sonuçlar, tüm modellerde iyileştirilmiş görüntülerin daha yüksek doğruluk sağladığını göstermiştir. Çalışmanın ikinci aşamasında, en başarılı iki model olan ResNet101 ve ResNet152 üzerinde farklı aktivasyon fonksiyonları test edilmiştir. Önerilen hibrit aktivasyon fonksiyonu ile ResNet101 %98,42, ResNet152 ise %97,20 doğruluk oranına ulaşarak en yüksek performansı göstermiştir. Bu bulgular, önerilen yöntemin sınıflandırma başarısını önemli ölçüde artırdığını ortaya koymaktadır.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Beyin tümörü sınıflandırması</kwd>
                                                    <kwd>  MRI görüntü</kwd>
                                                    <kwd>  hibrit aktivasyon fonksiyonları</kwd>
                                                    <kwd>  transfer öğrenme</kwd>
                                                    <kwd>  tıbbi görüntü</kwd>
                                            </kwd-group>
                            
                                                                                                                                                    </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">1.	Sitburana O., Ondo W.G., Brain Magnetic Resonance Imaging (MRI) in Parkinsonian Disorders, Parkinsonism &amp; Related Disorders, 15(3), 165–174, 2009.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">2.	Olanow C.W., Hauser R.A., Magnetic Resonance Imaging in Neurodegenerative Diseases, Neurodegenerative Diseases, 445–469, 1994.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">3.	Litjens G., Kooi T., Bejnordi B.E., Setio A.A.A., Ciompi F., Ghafoorian M., Sánchez C.I., A Survey on Deep Learning in Medical Image Analysis, Medical Image Analysis, 42, 60–88, 2017.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">4.	LeCun Y., Bengio Y., Hinton G., Deep Learning, Nature, 521(7553), 436–444, 2015.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">5.	Patel S., Bharath K.P., Balaji S., Muthu R.K., Comparative Study on Histogram Equalization Techniques for Medical Image Enhancement, Soft Computing for Problem Solving, 1, 657–669, 2018.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">6.	Jähne B., Digital Image Processing, Springer Science &amp; Business Media, Berlin, Germany, 2005.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">7.	Rajinikanth V., Priya E., Lin H., Lin F., Hybrid Image Processing Methods for Medical Image Examination, CRC Press, Boca Raton, USA, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">8.	LeCun Y., Bottou L., Bengio Y., Haffner P., Gradient-Based Learning Applied to Document Recognition, Proceedings of the IEEE, 86(11), 2278–2324, 1998.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">9.	Kamnitsas K., Ledig C., Newcombe V.F., Simpson J.P., Kane A.D., Menon D.K., Glocker B., Efficient Multi-Scale 3D CNN with Fully Connected CRF for Accurate Brain Lesion Segmentation, Medical Image Analysis, 36, 61–78, 2017.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">10.	Peng S., Chen W., Sun J., Liu B., Multi-Scale 3D U-Nets: An Approach to Automatic Segmentation of Brain Tumor, International Journal of Imaging Systems and Technology, 30(1), 5–17, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">11.	Nazir M., Wahid F., Ali Khan S., A Simple and Intelligent Approach for Brain MRI Classification, Journal of Intelligent &amp; Fuzzy Systems, 28(3), 1127–1135, 2015.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">12.	Korolev S., Safiullin A., Belyaev M., Dodonova Y., Residual and Plain Convolutional Neural Networks for 3D Brain MRI Classification, IEEE ISBI, Washington DC, USA, 835–838, April 2017.</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">13.	Zhang Y., Dong Z., Wu L., Wang S., A Hybrid Method for MRI Brain Image Classification, Expert Systems with Applications, 38(8), 10049–10053, 2011.</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">14.	Assam M., Kanwal H., Farooq U., Shah S.K., Mehmood A., Choi G.S., An Efficient Classification of MRI Brain Images, IEEE Access, 9, 33313–33322, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">15.	Fayaz M., Torokeldiev N., Turdumamatov S., Qureshi M.S., Qureshi M.B., Gwak J., An Efficient Methodology for Brain MRI Classification Based on DWT and Convolutional Neural Network, Sensors, 21(22), 7480, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">16.	Badža M.M., Barjaktarović M.Č., Classification of Brain Tumors from MRI Images Using a Convolutional Neural Network, Applied Sciences, 10(6), 1999, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref17">
                        <label>17</label>
                        <mixed-citation publication-type="journal">17.	Abiwinanda N., Hanif M., Hesaputra S.T., Handayani A., Mengko T.R., Brain Tumor Classification Using Convolutional Neural Network, World Congress on Medical Physics and Biomedical Engineering, 183–189, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref18">
                        <label>18</label>
                        <mixed-citation publication-type="journal">18.	Vankdothu R., Hameed M.A., Brain Tumor MRI Images Identification and Classification Based on the Recurrent Convolutional Neural Network, Measurement: Sensors, 24, 100412, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref19">
                        <label>19</label>
                        <mixed-citation publication-type="journal">19.	Chelghoum R., Ikhlef A., Hameurlaine A., Jacquir S., Transfer Learning Using Convolutional Neural Network Architectures for Brain Tumor Classification from MRI Images, IFIP International Conference on Artificial Intelligence Applications and Innovations, 189–200, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref20">
                        <label>20</label>
                        <mixed-citation publication-type="journal">20.	Çinar A., Yildirim M., Detection of Tumors on Brain MRI Images Using the Hybrid Convolutional Neural Network Architecture, Medical Hypotheses, 139, 109684, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref21">
                        <label>21</label>
                        <mixed-citation publication-type="journal">21.	Yazdan S.A., Ahmad R., Iqbal N., Rizwan A., Khan A.N., Kim D.H., An Efficient Multi-Scale Convolutional Neural Network Based Multi-Class Brain MRI Classification for SaMD, Tomography, 8(4), 1905–1927, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref22">
                        <label>22</label>
                        <mixed-citation publication-type="journal">22.	Toğaçar M., Cömert Z., Ergen B., Classification of Brain MRI Using Hyper Column Technique with Convolutional Neural Network and Feature Selection Method, Expert Systems with Applications, 149, 113274, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref23">
                        <label>23</label>
                        <mixed-citation publication-type="journal">23.	Jibon F.A., Khandaker M.U., Miraz M.H., Thakur H., Rabby F., Tamam N., Osman H., Cancerous and Non-Cancerous Brain MRI Classification Method Based on Convolutional Neural Network and Log-Polar Transformation, Healthcare, 10(9), 1801, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref24">
                        <label>24</label>
                        <mixed-citation publication-type="journal">24.	Abd El Kader I., Xu G., Shuai Z., Saminu S., Javaid I., Salim Ahmad I., Differential Deep Convolutional Neural Network Model for Brain Tumor Classification, Brain Sciences, 11(3), 352, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref25">
                        <label>25</label>
                        <mixed-citation publication-type="journal">25.	Mzoughi H., Njeh I., Wali A., Slima M.B., BenHamida A., Mhiri C., Mahfoudhe K.B., Deep Multi-Scale 3D Convolutional Neural Network (CNN) for MRI Gliomas Brain Tumor Classification, Journal of Digital Imaging, 33, 903–915, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref26">
                        <label>26</label>
                        <mixed-citation publication-type="journal">26.	Musallam A.S., Sherif A.S., Hussein M.K., A New Convolutional Neural Network Architecture for Automatic Detection of Brain Tumors in Magnetic Resonance Imaging Images, IEEE Access, 10, 2775–2782, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref27">
                        <label>27</label>
                        <mixed-citation publication-type="journal">27.	Remzan N., Tahiry K., Farchi A., Brain Tumor Classification in Magnetic Resonance Imaging Images Using Convolutional Neural Network, International Journal of Electrical and Computer Engineering, 12(6), 6664–6672, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref28">
                        <label>28</label>
                        <mixed-citation publication-type="journal">28.	Talo M., Yildirim O., Baloglu U.B., Aydin G., Acharya U.R., Convolutional Neural Networks for Multi-Class Brain Disease Detection Using MRI Images, Computerized Medical Imaging and Graphics, 78, 101673, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref29">
                        <label>29</label>
                        <mixed-citation publication-type="journal">29.	Rahman T., Islam M.S., MRI Brain Tumor Detection and Classification Using Parallel Deep Convolutional Neural Networks, Measurement: Sensors, 26, 100694, 2023.</mixed-citation>
                    </ref>
                                    <ref id="ref30">
                        <label>30</label>
                        <mixed-citation publication-type="journal">30.	Choudhuri R., Halder A., Brain MRI Tumour Classification Using Quantum Classical Convolutional Neural Net Architecture, Neural Computing and Applications, 35(6), 4467–4478, 2023.</mixed-citation>
                    </ref>
                                    <ref id="ref31">
                        <label>31</label>
                        <mixed-citation publication-type="journal">31.	Hazarika R.A., Maji A.K., Kandar D., Jasinska E., Krejci P., Leonowicz Z., Jasinski M., An Approach for Classification of Alzheimer’s Disease Using Deep Neural Network and Brain Magnetic Resonance Imaging (MRI), Electronics, 12(3), 676, 2023.</mixed-citation>
                    </ref>
                                    <ref id="ref32">
                        <label>32</label>
                        <mixed-citation publication-type="journal">32.	Rahman T., Islam M.S., MRI Brain Tumor Classification Using Deep Convolutional Neural Network, International Conference on Innovations in Science, Engineering and Technology, 451–456, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref33">
                        <label>33</label>
                        <mixed-citation publication-type="journal">33.	Choudhury C.L., Mahanty C., Kumar R., Mishra B.K., Brain Tumor Detection and Classification Using Convolutional Neural Network and Deep Neural Network, International Conference on Computer Science, Engineering and Applications, 1–4, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref34">
                        <label>34</label>
                        <mixed-citation publication-type="journal">34.	Shen D., Wu G., Suk H.I., Deep Learning in Medical Image Analysis, Annual Review of Biomedical Engineering, 19(1), 221–248, 2017.</mixed-citation>
                    </ref>
                                    <ref id="ref35">
                        <label>35</label>
                        <mixed-citation publication-type="journal">35.	Razzak M.I., Naz S., Zaib A., Deep Learning for Medical Image Processing: Overview, Challenges and the Future, Classification in BioApps: Automation of Decision Making, 323–350, 2018.</mixed-citation>
                    </ref>
                                    <ref id="ref36">
                        <label>36</label>
                        <mixed-citation publication-type="journal">36.	Nickparvar M., Brain Tumor MRI Dataset, Kaggle, https://www.kaggle.com/datasets/masoudnickparvar/brain-tumor-mri-dataset, Erişim Tarihi: 25.02.2026.</mixed-citation>
                    </ref>
                                    <ref id="ref37">
                        <label>37</label>
                        <mixed-citation publication-type="journal">37.	Esteva A., Robicquet A., Ramsundar B., Kuleshov V., DePristo M., Chou K., Dean J., A Guide to Deep Learning in Healthcare, Nature Medicine, 25(1), 24–29, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref38">
                        <label>38</label>
                        <mixed-citation publication-type="journal">38.	Akkus Z., Galimzianova A., Hoogi A., Rubin D.L., Erickson B.J., Deep Learning for Brain MRI Segmentation: State of the Art and Future Directions, Journal of Digital Imaging, 30, 449–459, 2017.</mixed-citation>
                    </ref>
                                    <ref id="ref39">
                        <label>39</label>
                        <mixed-citation publication-type="journal">39.	Shaheen F., Verma B., Asafuddoula M., Impact of Automatic Feature Extraction in Deep Learning Architecture, International Conference on Digital Image Computing: Techniques and Applications, 1–8, 2016.</mixed-citation>
                    </ref>
                                    <ref id="ref40">
                        <label>40</label>
                        <mixed-citation publication-type="journal">40.	Wang S., Peng Y., Lu L., Lu Z., Bagheri M., Summers R.M., Deep Learning in Medical Image Analysis: A Review, Current Imaging and Labeling Systems, 14, 1449–1474, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref41">
                        <label>41</label>
                        <mixed-citation publication-type="journal">41.	Yu X., Wang J., Hong Q.Q., Teku R., Wang S.H., Zhang Y.D., Transfer Learning for Medical Images Analyses: A Survey, Neurocomputing, 489, 230–254, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref42">
                        <label>42</label>
                        <mixed-citation publication-type="journal">42.	Krizhevsky A., Sutskever I., Hinton G.E., Imagenet Classification with Deep Convolutional Neural Networks, Advances in Neural Information Processing Systems, 25, 1–9, 2012.</mixed-citation>
                    </ref>
                                    <ref id="ref43">
                        <label>43</label>
                        <mixed-citation publication-type="journal">43.	Gonzales R.C., Wintz P., Digital Image Processing, Addison-Wesley Longman Publishing, Boston, USA, 1987.</mixed-citation>
                    </ref>
                                    <ref id="ref44">
                        <label>44</label>
                        <mixed-citation publication-type="journal">44.	Vrbančič G., Podgorelec V., Transfer Learning with Adaptive Fine-Tuning, IEEE Access, 8, 196197–196211, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref45">
                        <label>45</label>
                        <mixed-citation publication-type="journal">45.	Pan S.J., Yang Q., A Survey on Transfer Learning, IEEE Transactions on Knowledge and Data Engineering, 22(10), 1345–1359, 2009.</mixed-citation>
                    </ref>
                                    <ref id="ref46">
                        <label>46</label>
                        <mixed-citation publication-type="journal">46.	Glorot X., Bengio Y., Understanding the Difficulty of Training Deep Feedforward Neural Networks, International Conference on Artificial Intelligence and Statistics (AISTATS), 249–256, 2010.</mixed-citation>
                    </ref>
                                    <ref id="ref47">
                        <label>47</label>
                        <mixed-citation publication-type="journal">47.	Hinton G.E., Deng L., Yu D., Dahl G.E., Mohamed A.R., Deep Neural Networks for Acoustic Modeling in Speech Recognition, IEEE Signal Processing Magazine, 29(6), 82–97, 2012.</mixed-citation>
                    </ref>
                                    <ref id="ref48">
                        <label>48</label>
                        <mixed-citation publication-type="journal">48.	He K., Zhang X., Ren S., Sun J., Delving Deep into Rectifiers: Surpassing Human-Level Performance on ImageNet Classification, arXiv:1502.01852, 2015.</mixed-citation>
                    </ref>
                                    <ref id="ref49">
                        <label>49</label>
                        <mixed-citation publication-type="journal">49.	LeCun Y., Bottou L., Orr G.B., Müller K.R., Efficient BackProp, Neural Networks: Tricks of the Trade, 9–48, 2012.</mixed-citation>
                    </ref>
                                    <ref id="ref50">
                        <label>50</label>
                        <mixed-citation publication-type="journal">50.	Bishop C.M., Pattern Recognition and Machine Learning, Springer, New York, USA, 2006.</mixed-citation>
                    </ref>
                                    <ref id="ref51">
                        <label>51</label>
                        <mixed-citation publication-type="journal">51.	Mastromichalakis S., Parametric Leaky Tanh: A New Hybrid Activation Function for Deep Learning, arXiv:2310.07720, 2023.</mixed-citation>
                    </ref>
                                    <ref id="ref52">
                        <label>52</label>
                        <mixed-citation publication-type="journal">52.	Nair V., Hinton G.E., Rectified Linear Units Improve Restricted Boltzmann Machines, International Conference on Machine Learning, 807–814, 2010.</mixed-citation>
                    </ref>
                                    <ref id="ref53">
                        <label>53</label>
                        <mixed-citation publication-type="journal">53.	Goodfellow I., Bengio Y., Courville A., Deep Learning, MIT Press, Cambridge, USA, 2016.</mixed-citation>
                    </ref>
                                    <ref id="ref54">
                        <label>54</label>
                        <mixed-citation publication-type="journal">54.	Bengio Y., Learning Deep Architectures for AI, Foundations and Trends in Machine Learning, 2(1), 1–127, 2009.</mixed-citation>
                    </ref>
                                    <ref id="ref55">
                        <label>55</label>
                        <mixed-citation publication-type="journal">55.	Esteva A., Kuprel B., Novoa R.A., Dermatologist-Level Classification of Skin Cancer with Deep Neural Networks, Nature, 542(7639), 115–118, 2017.</mixed-citation>
                    </ref>
                                    <ref id="ref56">
                        <label>56</label>
                        <mixed-citation publication-type="journal">56.	Jaiswal A.K., Tiwari P., Kumar S., Gupta D., Khanna A., Rodrigues J.J., Identifying Pneumonia in Chest X-Rays: A Deep Learning Approach, Measurement, 145, 511–518, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref57">
                        <label>57</label>
                        <mixed-citation publication-type="journal">57.	Dubey S.R., Singh S.K., Chaudhuri B.B., Activation Functions in Deep Learning: A Comprehensive Survey and Benchmark, Neurocomputing, 503, 92–108, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref58">
                        <label>58</label>
                        <mixed-citation publication-type="journal">58.	Hao W., Yizhou W., Yaqin L., Zhili S., The Role of Activation Function in CNN, International Conference on Information Technology and Computer Application, 429–432, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref59">
                        <label>59</label>
                        <mixed-citation publication-type="journal">59.	Yadhav S.Y., Senthilkumar T., Jayanthy S., Kovilpillai J.J.A., Plant Disease Detection and Classification Using CNN Model with Optimized Activation Function, International Conference on Electronics and Sustainable Communication Systems, 564–569, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref60">
                        <label>60</label>
                        <mixed-citation publication-type="journal">60.	Kiliçarslan S., Celik M., RSigELU: A Nonlinear Activation Function for Deep Neural Networks, Expert Systems with Applications, 174, 114805, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref61">
                        <label>61</label>
                        <mixed-citation publication-type="journal">61.	Huang Z., Du X., Chen L., Li Y., Liu M., Chou Y., Jin L., Convolutional Neural Network Based on Complex Networks for Brain Tumor Image Classification with a Modified Activation Function, IEEE Access, 8, 89281–89290, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref62">
                        <label>62</label>
                        <mixed-citation publication-type="journal">62.	Wang J., Zhu H., Wang S.H., Zhang Y.D., A Review of Deep Learning on Medical Image Analysis, Mobile Networks and Applications, 26(1), 351–380, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref63">
                        <label>63</label>
                        <mixed-citation publication-type="journal">63.	Shinde V., Deep Learning Approaches for Medical Image Analysis and Disease Diagnosis, International Journal of Multidisciplinary Innovation and Research Methodology, 2(2), 57–66, 2023.</mixed-citation>
                    </ref>
                                    <ref id="ref64">
                        <label>64</label>
                        <mixed-citation publication-type="journal">64.	Hu M., Zhong Y., Xie S., Lv H., Lv Z., Fuzzy System Based Medical Image Processing for Brain Disease Prediction, Frontiers in Neuroscience, 15, 714318, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref65">
                        <label>65</label>
                        <mixed-citation publication-type="journal">65.	Bhattacharya S., Maddikunta P.K.R., Pham Q.V., Gadekallu T.R., Chowdhary C.L., Alazab M., Piran M.J., Deep Learning and Medical Image Processing for Coronavirus (COVID-19) Pandemic: A Survey, Sustainable Cities and Society, 65, 102589, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref66">
                        <label>66</label>
                        <mixed-citation publication-type="journal">66.	Suganyadevi S., Seethalakshmi V., Balasamy K., A Review on Deep Learning in Medical Image Analysis, International Journal of Multimedia Information Retrieval, 11(1), 19–38, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref67">
                        <label>67</label>
                        <mixed-citation publication-type="journal">67.	Chowdhary C.L., Acharjya D.P., Segmentation and Feature Extraction in Medical Imaging: A Systematic Review, Procedia Computer Science, 167, 26–36, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref68">
                        <label>68</label>
                        <mixed-citation publication-type="journal">68.	Atik İ.İ., Pneumonia detection on chest x-ray images using residual convolutional neural network, Journal of the Faculty of Engineering and Architecture of Gazi University, 39(3), 1719–1731, 2024.</mixed-citation>
                    </ref>
                                    <ref id="ref69">
                        <label>69</label>
                        <mixed-citation publication-type="journal">69.	Güler H., Avcı D., Ulaş M., Omma T., In-depth analysis of machine learning models and explainable artificial intelligence methods in diabetes diagnosis, Journal of the Faculty of Engineering and Architecture of Gazi University, 40(3), 1995–2012, 2025.</mixed-citation>
                    </ref>
                                    <ref id="ref70">
                        <label>70</label>
                        <mixed-citation publication-type="journal">70.	Kesav N., Jibukumar M.G., Efficient and Low Complex Architecture for Detection and Classification of Brain Tumor Using RCNN with Two Channel CNN, Journal of King Saud University-Computer and Information Sciences, 34(8), 6229–6242, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref71">
                        <label>71</label>
                        <mixed-citation publication-type="journal">71.	Amin J., Sharif M., Haldorai A., Yasmin M., Nayak R.S., Brain Tumor Detection and Classification Using Machine Learning: A Comprehensive Survey, Complex &amp; Intelligent Systems, 8(4), 3161–3183, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref72">
                        <label>72</label>
                        <mixed-citation publication-type="journal">72.	Jia Z., Chen D., Brain Tumor Identification and Classification of MRI Images Using Deep Learning Techniques, IEEE Access, 8, 1–12, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref73">
                        <label>73</label>
                        <mixed-citation publication-type="journal">73.	Khairandish M.O., Sharma M., Jain V., Chatterjee J.M., Jhanjhi N.Z., A Hybrid CNN-SVM Threshold Segmentation Approach for Tumor Detection and Classification of MRI Brain Images, IRBM, 43 (4), 290–299, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref74">
                        <label>74</label>
                        <mixed-citation publication-type="journal">74.	Arif M., Ajesh F., Shamsudheen S., Geman O., Izdrui D., Vicoveanu D., Brain Tumor Detection and Classification by MRI Using Biologically Inspired Orthogonal Wavelet Transform and Deep Learning Techniques (Retracted), Journal of Healthcare Engineering, 2022, 2693621, 2022.</mixed-citation>
                    </ref>
                                    <ref id="ref75">
                        <label>75</label>
                        <mixed-citation publication-type="journal">75.	Kandimalla S.Y., Vamsi D.M., Bhavani S., VM M., Recent Methods and Challenges in Brain Tumor Detection Using Medical Image Processing, Recent Patents on Engineering, 17 (5), 8–23, 2023.</mixed-citation>
                    </ref>
                                    <ref id="ref76">
                        <label>76</label>
                        <mixed-citation publication-type="journal">76.	Tazin T., Sarker S., Gupta P., Ayaz F.I., Islam S., Monirujjaman Khan M., Alshazly H., A Robust and Novel Approach for Brain Tumor Classification Using Convolutional Neural Network (Retracted), Computational Intelligence and Neuroscience, 2021, 2392395, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref77">
                        <label>77</label>
                        <mixed-citation publication-type="journal">77.	Hossain T., Shishir F.S., Ashraf M., Al Nasim M.A., Shah F.M., Brain Tumor Detection Using Convolutional Neural Network, International Conference on Advances in Science, Engineering and Robotics Technology, 1–6, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref78">
                        <label>78</label>
                        <mixed-citation publication-type="journal">78.	Seetha J., Raja S.S., Brain Tumor Classification Using Convolutional Neural Networks, Biomedical &amp; Pharmacology Journal, 11 (3), 1457–1464, 2018.</mixed-citation>
                    </ref>
                                    <ref id="ref79">
                        <label>79</label>
                        <mixed-citation publication-type="journal">79.	Kalkan M., Guzel M.S., Ekinci F., Akcapinar Sezer E., Asuroglu T., Comparative Analysis of Deep Learning Methods on CT Images for Lung Cancer Specification, Cancers, 16 (19), 3321, 2024.</mixed-citation>
                    </ref>
                                    <ref id="ref80">
                        <label>80</label>
                        <mixed-citation publication-type="journal">80.	Emek Soylu B., Guzel M.S., Bostanci G.E., Ekinci F., Asuroglu T., Acici K., Deep-Learning-Based Approaches for Semantic Segmentation of Natural Scene Images: A Review, Electronics, 12 (12), 2730, 2023.</mixed-citation>
                    </ref>
                                    <ref id="ref81">
                        <label>81</label>
                        <mixed-citation publication-type="journal">81.	Atilkan Y., Kirik B., Acici K., Benzer R., Ekinci F., Guzel M.S., Asuroglu T., Advancing Crayfish Disease Detection: A Comparative Study of Deep Learning and Canonical Machine Learning Techniques, Applied Sciences, 14 (14), 6211, 2024.</mixed-citation>
                    </ref>
                                    <ref id="ref82">
                        <label>82</label>
                        <mixed-citation publication-type="journal">82.	Ozsari S., Kumru E., Ekinci F., Akata I., Guzel M.S., Acici K., Asuroglu T., Deep Learning-Based Classification of Macrofungi: Comparative Analysis of Advanced Models for Accurate Fungi Identification, Sensors, 24 (22), 7189, 2024.</mixed-citation>
                    </ref>
                                    <ref id="ref83">
                        <label>83</label>
                        <mixed-citation publication-type="journal">83.	Ekinci F., Ugurlu G., Ozcan G.S., Acici K., Asuroglu T., Kumru E., Akata I., Classification of Mycena and Marasmius Species Using Deep Learning Models: An Ecological and Taxonomic Approach, Sensors, 25 (6), 1642, 2025.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
