Araştırma Makalesi

The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia

Cilt: 34 Sayı: 5 31 Ekim 2024
PDF İndir
TR EN

The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia

Öz

Background: Pneumothorax and lymphopenia regarded as poor prognostic factors in covid-19 pneumonia.In this study, we aimed to determine whether there is a relationship between pneumothorax and lymphopenia in patients admitted to the intensive care unit due to COVID-19 pneumonia and evaluate whether lymphocyte count can be used to predict the development of pneumothorax. Methods: We reviewed the records of 50 patients with COVID-19 pneumonia retrospectively who developed pneumothorax and underwent tube thoracostomy at our hospital's intesive care units Results : There were 32 women and 18 men with a mean age of 67.98 years.Of the patients who developed pneumothorax, 78% were intubated. 86% of the patients with pneumothorax died.The risk of mortality in patients with pneumothorax decreased 0.198 times as lymphocyte count increased. In ROC curve analysis based on intubation status, a cut-off value of 1.02 for lymphocyte count is statistically significant. Conclusions: In this study, we observed that intubated patients had a high likelihood of developing pneumothorax and that concomitant deep lymphopenia was directly associated with mortality. The results highlight that during intensive care follow-up, it must be kept in mind that poor prognostic factors can interact to result in more serious prognostic implications

Anahtar Kelimeler

Covid-19, intensive care unit, lymphopenia, pneumothorax

Kaynakça

  1. World Health Organization. (‎2020)‎. Clinical management of COVID-19: interim guidance, World Health Organization, 2020.
  2. Elder C, Bawa S, Anderson D, Atkinson S, Etzel J. Moritz T. Expectant management of pneumothorax in intubated COVID-19 positive patients: a case series. J Cardiothorac Surg 2020;15(1):263.
  3. Martinelli AW, Ingle T, Newman J, Nadeem I, Jackson K, Lane ND, et. al. COVID-19 and pneumothorax: a multicentre retrospective case series. Eur Respir J 2020;56(5):2002697.
  4. Zantah M, Dominguez Castillo E, Townsend R, Dikengil F, Criner GJ. Pneumothorax in COVID-19 disease- incidence and clinical characteristics. Respir Res 2020;21(1):236.
  5. Talan L, Şaşal Solmaz FG, Ercan U, Akdemir Kalkan İ, Yenigün BM, Yüksel C, et. al. COVID-19 pneumonia and pneumothorax: case series. Tuberk Toraks 2020;68(4):437-43.
  6. Xu Y, Li S, Liu H. Clinical outcomes of pleural drainage on pneumothorax and hydrothorax in critically ill patients with COVID-19: A case series with literature review. Heart Lung 2021;50(2):213-19.
  7. Ulutas H, Celik MR, Gulcek I, et al. Management of spontaneous pneumothorax in patients with COVID-19. Interact Cardiovasc Thorac Surg. 2022; 34 (6): 1002-1010. doi:10.1093/icvts/ivab280
  8. Al-Ani A, AbuZayda H, Ahmed H, et al. Limitation of tube thoracostomy in treating pneumothorax in COVID-19 infected patients. A retrospective cohort study. Ann Med Surg (Lond). 2022;80:104171. doi:10.1016/j.amsu.2022.104171
  9. Henry BM, de Oliveira MHS, Benoit S, Plebani M, Lippi G. Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis. Clin Chem Lab Med 2020;58(7):1021-28.
  10. Ponti G, Maccaferri M, Ruini C, Tomasi A, Ozben T. Biomarkers associated with COVID-19 disease progression. Crit Rev Clin Lab Sci 2020;57(6):389-399.

Kaynak Göster

APA
Şahinoğlu, T. (2024). The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia. Genel Tıp Dergisi, 34(5), 616-623. https://doi.org/10.54005/geneltip.1411168
AMA
1.Şahinoğlu T. The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia. Genel Tıp Derg. 2024;34(5):616-623. doi:10.54005/geneltip.1411168
Chicago
Şahinoğlu, Tuba. 2024. “The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia”. Genel Tıp Dergisi 34 (5): 616-23. https://doi.org/10.54005/geneltip.1411168.
EndNote
Şahinoğlu T (01 Ekim 2024) The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia. Genel Tıp Dergisi 34 5 616–623.
IEEE
[1]T. Şahinoğlu, “The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia”, Genel Tıp Derg, c. 34, sy 5, ss. 616–623, Eki. 2024, doi: 10.54005/geneltip.1411168.
ISNAD
Şahinoğlu, Tuba. “The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia”. Genel Tıp Dergisi 34/5 (01 Ekim 2024): 616-623. https://doi.org/10.54005/geneltip.1411168.
JAMA
1.Şahinoğlu T. The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia. Genel Tıp Derg. 2024;34:616–623.
MLA
Şahinoğlu, Tuba. “The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia”. Genel Tıp Dergisi, c. 34, sy 5, Ekim 2024, ss. 616-23, doi:10.54005/geneltip.1411168.
Vancouver
1.Tuba Şahinoğlu. The Relationship Between Pneumothorax and Lymphopenia In Patients with Covid-19 Pneumonia. Genel Tıp Derg. 01 Ekim 2024;34(5):616-23. doi:10.54005/geneltip.1411168