Investigation of Microstructure and Biocompatibility Properties of Ti-16Nb-4Sn Alloy Produced by Powder Metallurgy for Implantation Applications

Abstract

In this study, Ti-16Nb-4Sn ternary alloy was produced as two different porosity by conventional powder metallurgy method. During production, ammonium bicarbonate was used as a volatile additive to increase the porosity. Considering the mass and size dimensions of the samples, the general porosities were determined as 13.62 and 56.32%. Phase analysis and changes in microstructure of sintered samples were examined using XRD, optical microscope, SEM-EDS techniques. In XRD analysis results, it was determined that the structure consisted of β and  phases. As a result of SEM-EDS examinations, it was determined that the structure consisted of two types of morphology: dark grey belonging to  phase and light grey belonging to β phase. The strengths of the samples were examined by performing a uniaxial compression test. As expected, it was determined that the compressive strength of the samples decreased with the increased porosity. Biocompatibility properties of samples with ideal pores in terms of biocompatibility (multi-porous) were examined in vivo using Sprague Dawley female rat. It was determined that there was no toxic and allergic interaction at the implantation site. Thus, it is predicted that the samples can be used as an ideal implant material in terms of biocompatibility.

İmplantasyon Uygulamaları İçin Toz Metalurjisi ile Üretilen Ti-16Nb-4Sn Alaşımının Mikroyapı ve Biyouyumluluk Özelliklerinin İncelenmesi

Abstract

Bu çalışmada, Ti-16Nb-4Sn alaşımları az gözenekli ve çok gözenekli olarak geleneksel toz metalürjisi yöntemi ile üretildi. Sinterlenen numunelerin faz analizleri ve mikroyapılarında meydana gelen değişimler; XRD, optik mikroskop, SEM-EDS teknikleri kullanılarak incelendi. XRD analiz sonuçlarında yapının β ve  fazlarından oluştuğu tespit edildi. SEM-EDS incelemeleri sonucunda yapının,  fazın ait koyu gri ve β fazına ait açık gri olmak üzere iki tür morfolojiden oluştuğu tespit edildi. Gözenek oranı azaldıkça daha homojen bir yapının oluştuğu görüldü. Numunelerin gözenek oranının artması ile basma dayanımlarının azaldığı görülmektedir. Çok gözenekli numunelerin in vivo ortamda biyouyumluluk özellikleri incelendiğinde implantasyon bölgesinde toksik ve alerjik etkileşimin olmadığı görülmekte ve böylece numunelerin biyouyumluluk açısında ideal bir implant malzemesi olarak kullanılabileceği öngörülmektedir.

Keywords

• TiNbSn Alaşımları
• Gözenekli Biyomalzemeler
• Mikroyapı.

References

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