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            <front>

                <journal-meta>
                                    <journal-id></journal-id>
            <journal-title-group>
                                                                                    <journal-title>Geleneksel ve Tamamlayıcı Anadolu Tıbbı Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2757-7643</issn>
                                                                                            <publisher>
                    <publisher-name>Sakarya Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Pharmacology and Pharmaceutical Sciences</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Eczacılık ve İlaç Bilimleri</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Kadim Çağlardan Günümüze Tedavide Tıbbi ve Aromatik Bitkilerin Rolü</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="en">
                                    <trans-title>The Role of Medicinal and Aromatic Plants in the Treatment From Ancient Times</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-8547-6523</contrib-id>
                                                                <name>
                                    <surname>Gökçe</surname>
                                    <given-names>Aksanur</given-names>
                                </name>
                                                                    <aff>AMASYA UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF FAMILY MEDICINE</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-7379-5436</contrib-id>
                                                                <name>
                                    <surname>Erdoğan Orhan</surname>
                                    <given-names>İlkay</given-names>
                                </name>
                                                                    <aff>GAZİ ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20250328">
                    <day>03</day>
                    <month>28</month>
                    <year>2025</year>
                </pub-date>
                                        <volume>5</volume>
                                        <issue>1</issue>
                                        <fpage>1</fpage>
                                        <lpage>13</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20230510">
                        <day>05</day>
                        <month>10</month>
                        <year>2023</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20240103">
                        <day>01</day>
                        <month>03</month>
                        <year>2024</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2019, Geleneksel ve Tamamlayıcı Anadolu Tıbbı Dergisi</copyright-statement>
                    <copyright-year>2019</copyright-year>
                    <copyright-holder>Geleneksel ve Tamamlayıcı Anadolu Tıbbı Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Bitkiler çok eski çağlardan bu yana sağlık, besin ve bazı diğer amaçlarla kullanılarak insanlığa hizmet etmektedir. Dolayısıyla bitkilerin tedavi amacıyla kullanıldığı yüzyıllar boyunca hekimlik ve eczacılık birbirinden ayrılmayan iki meslek olagelmiştir. Tarih öncesi çağlardan itibaren bitkilerin tedavi amacıyla kullanımına dair pek çok yazılı kaynak mevcuttur. Tedavide kullanılan bitkilerin bilimsel süzgeçten geçirilerek kullanımlarının sağlanması toplum sağlığı açısından önem ihtiva etmektedir. Tıbbın ve bitkilerle tedavinin gelişim sürecine bakıldığında, bu derlemede başta Mezopotamya kökenli olmak üzere kadim medeniyetler (Sümer, Babil, Hitit, Yunan, vs) ile Hint, Çin, Japon ve İslam medeniyetlerinin katkıları gözden geçirilmiştir. Bu derleme ile kadim bilgiler gün ışığına çıkartılmış olup, geleneksel bilgilerin modern fitoterapi araştırmalarında kullanılabilmesi için literatüre katkıda bulunulmuştur.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="en">
                            <p>Plants have served humanity for health, food, and other purposes since ancient times. Therefore, medicine and pharmacy have been two professions that are not separated from each other for centuries, when plants were used for therapeutic purposes. There are many written sources about the therapeutic use of plants since prehistoric times. Ensuring the use of the plants used in treatment by passing them through a scientific filter is important in terms of public health. In this review, contributions of the ancient civilizations, particularly in Mesopotamia (e.g., Sumerian, Babillion, Hittite, Greek) as well as Indian, Chinese, Japanese, and Islamic civilizations, are briefly reviewed in the “General Information” section, considering the development process of medicine and herbal therapy.</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Tıbbi bitki</kwd>
                                                    <kwd>  Bitkilerle tedavi</kwd>
                                                    <kwd>  Fitoterapi</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="en">
                                                    <kwd>Medicinal plant</kwd>
                                                    <kwd>  Therapy with plant</kwd>
                                                    <kwd>  Phytotherapy</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">Bayat AH. Tıp Tarihi Kitabı. İstanbul: Merkez Efendi Geleneksel Tıp Derneği, 2016: p. 34-240.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">Lewis P. Tıp Tarihi (Çev. Dr. Güdücü N.), İstanbul: Hürriyet Matbaacılık A.Ş., 1998: p. 10.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">Ronan CA. Bilim Tarihi. (Çev. İhsanoğlu E., Günergun F), Ankara: TÜBİTAK, 2003, p. 36.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">Karaöz Arıhan S. Antik dönemde tıp ve bitkisel tedavi, Yüksek lisans tezi, Ankara Üniversitesi Sosyal Bilimler Enstitüsü, Ankara, Türkiye, 2003.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">Lyons AS, Petrucelli JR. Medicine: An Illustrated History. New York: Harry N. Abrams Inc. Publishers, 1978: p. 12.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">Asil E. Dünden bugüne eczacılık. Meslekiçi Sürekli Eğitim Dergisi (MİSED). 2001;12: 4-19.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">Hajar R. The pulse in ancient medicine part 1. Heart Views. 2018;19(1):36-43.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">Mandacı Uncu E. Eski Mezopotamya’da tıp. Int J History. 2013;5(5):107-118.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">Retief FP, Cilliers L. Mesopotamian medicine. South Afr Med J. 2007;97(1):27-30.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">Dafni A, Boeck B. Revisiting the medicinal plants of the Bible and the Holy Land. Res Outreach. 2020;114:122-125.</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">Sarı NH, Altıntaş A, Başağaoğlu İ, Özaydın Z, Doğan H, Ülman YI, Hot İ. Tıp Tarihi ve Tıp Etiği Ders Kitabı. İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, İstanbul: İstanbul Üniversitesi Yayın No. 00249, Fakülte Yayın No. 4711, 55-106, 2007.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">Ünal A. Hitit Tıbbının Ana Hatları. Türk Tarih Kurumu, 1980:14(175):475-495.</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">Jaiswal YS, Williams LL. A glimpse of Ayurveda – The forgotten history and principles of Indian traditional medicine. J Tradit Complement Med. 2017;7(1):50-53.</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">Ravishankar B, Shukla VJ. Indian systems of medicine: A brief profile. Afr J Tradit Complement Altern Med. 2007;4(3):319-337.</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">Bodeker GC. Ayurvedic medicine. CMAJ. 1991;145(1):9-12.</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">Hankey A. Ayurvedic physiology and etiology: Ayurvedo Amritanaam. The doshas and their functioning in terms of contemporary biology and physical chemistry. J Altern Complement Med. 2001;7(5):567-574.</mixed-citation>
                    </ref>
                                    <ref id="ref17">
                        <label>17</label>
                        <mixed-citation publication-type="journal">Zhu YP, Woerdenbag HJ. Traditional Chinese herbal medicine. Pharm World Sci. 1995;17(4):103-112.</mixed-citation>
                    </ref>
                                    <ref id="ref18">
                        <label>18</label>
                        <mixed-citation publication-type="journal">Zhang ZJ, Wang XM, McAlonan GM. Neural acupuncture unit: A new concept for interpreting effects and mechanisms of acupuncture. Evid-Based Complement Altern Med. 2012;2012:429412.</mixed-citation>
                    </ref>
                                    <ref id="ref19">
                        <label>19</label>
                        <mixed-citation publication-type="journal">Motoo Y, Arai I, Hyodo I, et al. Current status of Kampo (Japanese herbal) medicines in Japanese clinical practice guidelines. Complement Ther Med. 2009;17(3):147-154.</mixed-citation>
                    </ref>
                                    <ref id="ref20">
                        <label>20</label>
                        <mixed-citation publication-type="journal">Motoo Y, Seki T, Tsutani K. Traditional Japanese medicine, Kampo: Its history and current status. Chin J Integr Med. 2011;17(2):85-87.</mixed-citation>
                    </ref>
                                    <ref id="ref21">
                        <label>21</label>
                        <mixed-citation publication-type="journal">Arai YC, Makino I, Ikemoto T et al. Kampo for the treatment of pain in Japan: A review. Pain Ther. 2020;9(1):161-170.</mixed-citation>
                    </ref>
                                    <ref id="ref22">
                        <label>22</label>
                        <mixed-citation publication-type="journal">Palgi P, Dorban J. An analysis of the self of the western physician: A study on the evolution of homo Hippocratus. Cult Med Psychiatry. 1997;21(3):261-281.</mixed-citation>
                    </ref>
                                    <ref id="ref23">
                        <label>23</label>
                        <mixed-citation publication-type="journal">Uğurlu MC. Hipokrat. Ank Üniv Tıp Fak Mecmuası. 1997;50(2):67-78.</mixed-citation>
                    </ref>
                                    <ref id="ref24">
                        <label>24</label>
                        <mixed-citation publication-type="journal">Singer C, Underwood EA. (1962). A Short History of Medicine (Second Edition), Oxford University Press, 12.</mixed-citation>
                    </ref>
                                    <ref id="ref25">
                        <label>25</label>
                        <mixed-citation publication-type="journal">Sadeghi S, Ghaffari F, Heydarirad G, et al. Galen&#039;s place in Avicenna&#039;s the canon of medicine: Respect, confirmation and criticism. J Integr Med. 2020;18(1):21-25.</mixed-citation>
                    </ref>
                                    <ref id="ref26">
                        <label>26</label>
                        <mixed-citation publication-type="journal">Afshar A, Tabrizi A. Razi and his concepts on bone and joint disorders. Arch Iran Med. 2020;23(9):624-628.</mixed-citation>
                    </ref>
                                    <ref id="ref27">
                        <label>27</label>
                        <mixed-citation publication-type="journal">Abivardi C. Iranian Entomology - An Introduction: Volume 1: Faunal Studies, Springer-Verlag, 2001.</mixed-citation>
                    </ref>
                                    <ref id="ref28">
                        <label>28</label>
                        <mixed-citation publication-type="journal">Ardi MN, Abdullah FM, Al-Tamimi S. Al Biruni: A Muslim critical thinker. Int J Nusantara Islam. 2016;4(1):1-12.</mixed-citation>
                    </ref>
                                    <ref id="ref29">
                        <label>29</label>
                        <mixed-citation publication-type="journal">Beyler F. Ebü’l-Kasım ez-Zehravi ve Kitabu’t-Tasrif adlı eseriyle ilgili Rusça araştırmalar. J Acad Soc Sci Studies. 2020;13(79): 431-443.</mixed-citation>
                    </ref>
                                    <ref id="ref30">
                        <label>30</label>
                        <mixed-citation publication-type="journal">Kahya E (çeviren). Kitab El-Tasrif Li Men Acize En At-Ta’lif. Ankara Nobel Tıp Kitabevleri, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref31">
                        <label>31</label>
                        <mixed-citation publication-type="journal">Acıduman A. İbn-i Sina&#039;nın bilim tarihindeki yeri: Kuhn’ca bir yaklaşımla. Ank Üniv Tıp Fak Mecmuası. 2002;55(2):115-122.</mixed-citation>
                    </ref>
                                    <ref id="ref32">
                        <label>32</label>
                        <mixed-citation publication-type="journal">Topkar K. Tercüme-i Müfredat-ı İbn Baytar. Sağlık Bilimleri Üniversitesi Yayınları, 2017.</mixed-citation>
                    </ref>
                                    <ref id="ref33">
                        <label>33</label>
                        <mixed-citation publication-type="journal">Dündar M, Emekli R, Şener E. Anadolu’daki tıbbın doğuşu, dünyadaki ilk tıp okulu olarak: Gevher Nesibe tıp medresesi ve darüşşifası. Bilimname. 2019;39:79-103.</mixed-citation>
                    </ref>
                                    <ref id="ref34">
                        <label>34</label>
                        <mixed-citation publication-type="journal">Ünver AS. Osmanlı Türklerinde Hekimlik ve Eczacılık Tarihi Hakkında. İstanbul: Hüsnütabiat Basımevi; 1952:22.</mixed-citation>
                    </ref>
                                    <ref id="ref35">
                        <label>35</label>
                        <mixed-citation publication-type="journal">Yılmaz N, Yılmaz C. Evliya Çelebi’nin seyahatnamesine göre Osmanlılarda sağlık hayatı. İçinde: Yılmaz N, Yılmaz C, editörler. Osmanlılarda Sağlık I. İstanbul: Biyofarma Yayınları; 2006:343-359.</mixed-citation>
                    </ref>
                                    <ref id="ref36">
                        <label>36</label>
                        <mixed-citation publication-type="journal">Bilgin A. Osmanlılarda ilaç yapımında kullanılan tıbbî bitkiler. İçinde: Yılmaz, N, Yılmaz, C, editörler. Osmanlılarda Sağlık I. İstanbul: Biyofarma Yayınları; 2006:257-263.</mixed-citation>
                    </ref>
                                    <ref id="ref37">
                        <label>37</label>
                        <mixed-citation publication-type="journal">Özvar E. Osmanlı dünyasında yazma eser üretkenliği. Sahn-ı Semân’dan Dârülfünûn’a, Osmanlı’da İlim ve Fikir Dünyası (Âlimler, Müesseseler ve Fikrî Eserler) - XVII. Yüzyıl, İlk baskı. İstanbul: Zeytinburnu Belediyesi Kültür Yayınları; 2017:19.</mixed-citation>
                    </ref>
                                    <ref id="ref38">
                        <label>38</label>
                        <mixed-citation publication-type="journal">Kaya E. Envâ-ı Emrâz: İnceleme-Metin-Dizin. Yüksek lisans tezi. Çanakkale; 2009.</mixed-citation>
                    </ref>
                                    <ref id="ref39">
                        <label>39</label>
                        <mixed-citation publication-type="journal">Bácskay A. Two Sumerian incantations against migraine (sag̃-ki-dab-ba) on amulets and cuneiform tablets. Revue d&#039;Assyriol d&#039;Archeol Orientale. 2019;113(1):175-188.</mixed-citation>
                    </ref>
                                    <ref id="ref40">
                        <label>40</label>
                        <mixed-citation publication-type="journal">Džaja P, Severin K. Veterinary profession in Antiquity. Vet Stanica. 2019;50(6):577-586.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
