Autism Spectrum Disorder, Microbiota And Nutritional Therapy Approaches

Abstract

Autism Spectrum Disorder (ASD) is a developmental disorder that causes problems related to communication, social, verbal and motor skills. Due to its increasing prevalence and non treatment, interest in autism is increasing day by day. New approaches to the treatment of autism are being developed by considering the factors and symptoms in the etiology. Today, the intestine, defined as the second brain, has been reported to be associated with changes in the microbiota in autism, as in many diseases.  As a result of changes in the brain due to increased intestinal permeability in autism, therapeutic approaches to regulate microbiota composition are being developed. Studies in the literature are mainly directed to probiotics and prebiotics, omega-3 fatty acids, ketogenic diets and gluten-free casein-free diets. The diet consumed is thought to be effective in ASD behaviors and reduce symptoms; however, there is no sufficient evidence-based study to establish medical nutrition therapy. In this review, the differences in intestinal microbiota and current dietary approaches in autism were evaluated.

Keywords

• autism,microbiota,diet,probiotic,omega-3

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