Yıl 2020, Cilt 2 , Sayı 1, Sayfalar 11 - 17 2020-04-30

Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes

Ebru KONDOLOT SOLAK [1] , Seçil KAYA [2]


This study presents that the controlled release of Hypericum perforatum (HP) from biofilm formation of sodium alginate (NaAlg). Its oil was incorporated in sodium alginate biofilm as a potential therapeutic agent. HP belongs from the family of Hypericaceae. HP is traditionally used for wound healing in Turkey and has medical importance. In addition, bacterial resistance of HP was investigated for against Staphylococcus aureus. Silver Sulfadiazine (SSD) was added in different concentration (0.5-2.0 w/v) to prepare the antibacterial biofilms. The addition of antibiotics and HP into the biofilm will ensure the delivery of all the necessary substances locally in the wound healing process. Biofilms were prepared by solvent casting method in different oil concentration (0.25-2.0 % v/v). The surface properties of biofilms were investigated by using Scanning Electron Microscopy (SEM), drug release profiles were studied at pH 5.5 and bacterial resistance of HP was investigated for against Staphylococcus aureus. As a result of our study, the new generation hydrogel wound dressing will, heal wounds effectively and quickly especially protecting the burns from microorganisms.
Hypericum Perforatum, , hydrogel, , controlled release
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Birincil Dil en
Konular Sağlık Bilimleri ve Hizmetleri
Bölüm Makaleler
Yazarlar

Yazar: Ebru KONDOLOT SOLAK (Sorumlu Yazar)
Kurum: GAZİ ÜNİVERSİTESİ, TEKNİK BİLİMLER MESLEK YÜKSEKOKULU
Ülke: Turkey


Orcid: 0000-0002-5939-3959
Yazar: Seçil KAYA
Kurum: Gazi Üniversitesi, Fen Bilimleri Enstitüsü, İleri Teknolojiler Anabilim Dalı
Ülke: Turkey


Destekleyen Kurum Gazi University Scientific Research Foundation
Proje Numarası 65/2018-01
Teşekkür We are grateful to the Gazi University Scientific Research Foundation (65/2018-01) for support of this study. Gazi University Photonic Application and Research Center, Gazi University Life Sciences Research and Application Center and METU Central Laboratory for their services in finalizing some necessary analyses in this study.
Tarihler

Yayımlanma Tarihi : 30 Nisan 2020

Bibtex @araştırma makalesi { guhes708420, journal = {Journal of Gazi University Health Sciences Institute}, issn = {2687-6353}, address = {guhes@gazi.edu.tr}, publisher = {Gazi Üniversitesi}, year = {2020}, volume = {2}, pages = {11 - 17}, doi = {}, title = {Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes}, key = {cite}, author = {Kondolot Solak, Ebru and Kaya, Seçil} }
APA Kondolot Solak, E , Kaya, S . (2020). Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes. Journal of Gazi University Health Sciences Institute , 2 (1) , 11-17 . Retrieved from https://dergipark.org.tr/tr/pub/guhes/issue/54114/708420
MLA Kondolot Solak, E , Kaya, S . "Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes". Journal of Gazi University Health Sciences Institute 2 (2020 ): 11-17 <https://dergipark.org.tr/tr/pub/guhes/issue/54114/708420>
Chicago Kondolot Solak, E , Kaya, S . "Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes". Journal of Gazi University Health Sciences Institute 2 (2020 ): 11-17
RIS TY - JOUR T1 - Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes AU - Ebru Kondolot Solak , Seçil Kaya Y1 - 2020 PY - 2020 N1 - DO - T2 - Journal of Gazi University Health Sciences Institute JF - Journal JO - JOR SP - 11 EP - 17 VL - 2 IS - 1 SN - 2687-6353- M3 - UR - Y2 - 2020 ER -
EndNote %0 Gazi Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes %A Ebru Kondolot Solak , Seçil Kaya %T Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes %D 2020 %J Journal of Gazi University Health Sciences Institute %P 2687-6353- %V 2 %N 1 %R %U
ISNAD Kondolot Solak, Ebru , Kaya, Seçil . "Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes". Journal of Gazi University Health Sciences Institute 2 / 1 (Nisan 2020): 11-17 .
AMA Kondolot Solak E , Kaya S . Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes. GUHES. 2020; 2(1): 11-17.
Vancouver Kondolot Solak E , Kaya S . Hypericum perforatum Releasing From Silver Sulphadiozine Loaded Sodium Alginate Membranes. Journal of Gazi University Health Sciences Institute. 2020; 2(1): 17-11.