The Relationship of Complete Urinalysis with Urine Culture in Infants Presenting with a Preliminary Diagnosis of Urinary Tract Infection

Yıl 2022, Cilt: 4 Sayı: 3, 152 - 157, 31.12.2022

Mehmet Cengiz Asuman Kıral

Öz

In this study, relationship of complete urinalysis (CUA) with urinary culture growth rates in infants admitted with a preliminary diagnosis of urinary tract infection (UTI) was examined. The files of 101 infants admitted with a preliminary diagnosis of UTI were reviewed retrospectively. Units used for the preliminary diagnosis of UTI; at CUA; Leukocyte>5, Leukocyte Esterase(LE) positivity, Nitrite Positivity, LE + Nitrite positivity were compared with the growth rate in urine culture. CUA samples were taken with sterile bags. Urine cultures were taken with a catheter from those with significant findings in CUA. While the rate of growth in urine culture was 67.4% in those with Leukocytes>5 in CUA, the rate of growth was 57.1% when Leukocytes were<5. While the rate of growth in urine culture was 76.1% in those with LE(+), it was 12.5% in those with LE(-). While the rate of growth in urine culture was 94.4% in those with nitrite(+), it was 44.7% in those with nitrite(-). While the growth rate in urine culture was 73.3% in those with LE(+)+Nitrite(+), it was 21.1% in those with LE(-)+Nitrite(-). When the relationship of CUA, which is required for the preliminary diagnosis of UTI, with the growth rates in urine culture, it was found that the highest growth rate was in those with Nitrite(+), but false negativity was also high. It is thought that the detection of LE(+) with the lowest false-negative rate in the reproduction of the urine culture is more reliable in diagnosing UTI.

Anahtar Kelimeler

Complete urinalysis, Urınary tract infection, Urine culture

Kaynakça

• Bachur, R., & Harper, M. B. (2001). Reliability of the urinalysis for predicting urinary tract infections in young febrile children. Archives of Pediatrics & Adolescent Medicine, 155(1), 60-65.
• Bonadio, W., & Maida, G. (2014). Urinary tract infection in outpatient febrile infants younger than 30 days of age: a 10-year evaluation. The Pediatric İnfectious Disease Journal, 33(4), 342-344.
• Davenport, M., & Shortliffe, L. M. D. (2018). Urinary tract infections, renal abscess, and other complex renal infections. Principles and Practice of Pediatric Infectious Diseases. 5th ed. Philadelphia, PA: Elsevier.
• Hoberman, A., Wald, E. R., Reynolds, E. A., Penchansky, L., & Charron, M. (1996). Is urine culture necessary to rule out urinary tract infection in young febrile children?. The Pediatric İnfectious Disease Journal, 15(4), 304-309.
• Korbel, L., Howell, M., & Spencer, J. D. (2017). The clinical diagnosis and management of urinary tract infections in children and adolescents. Paediatrics and İnternational Child Health, 37(4), 273-279.
• Kouri, T., Fogazzi, G., Gant, V., Hallander, H., Hofmann, W., & Guder, W. G. (2000). European urinalysis guidelines. Scandinavian Journal of Clinical and Laboratory İnvestigation, 60(sup231), 1-96.
• Newman, T. B., Bernzweig, J. A., Takayama, J. I., Finch, S. A., Wasserman, R. C., & Pantell, R. H. (2002). Urine testing and urinary tract infections in febrile infants seen in office settings: the Pediatric Research in Office Settings' Febrile Infant Study. Archives of Pediatrics & Adolescent Medicine, 156(1), 44-54.
• Okarska-Napierała, M., Wasilewska, A., & Kuchar, E. (2017). Urinary tract infection in children: Diagnosis, treatment, imaging–Comparison of current guidelines. Journal of Pediatric Urology, 13(6), 567-573.
• Roberts, K. B., Charney, E., Sweren, R. J., Ahonkhai, V. I., Bergman, D. A., Coulter, M. P., ... & Stein, M. T. (1983). Urinary tract infection in infants with unexplained fever: a collaborative study. The Journal of Pediatrics, 103(6), 864-867.
• Sezgin, F. M., & Nar, R. (2017). İdrar yolu enfeksiyonu ön tanılı çocuk hastaların idrar kültürü ve idrar analiz sonuçlarının değerlendirilmesi. Pamukkale Tıp Dergisi, 10(3), 242-248.
• Tarin, T., Shinghal, R., Dairiki Shortliffe, L.M. (2010) Pediatric urinary tractınfections. Pediatric Urology.2nd ed. 180-195. https://doi.org/10.1016/B978-1-4160-3204-5.00013-X
• Üstündağ, Y., Huysal, K., Eren, N., Avcı Sanlı, H., Karaca Ulusoy, A., Özkan, Ö., ... & İbiş, S. Ş. (2013). Süt çocuklarında kültür pozitifliği öngörüsünde idrar analiz sonuçlarının değerlendirilmesi. Türk Klinik Biyokimya Dergisi, 11(3), 87-92.
• Weiz, D., Seabrook, J. A., & Lim, R. K. (2008). Urinary nitrite is a significant predictor of pediatric UTI susceptibility to first and third–generation cephalosporins. Journal of Emergency Medicine, 39(1), 6-12.
• Zorbozan, N., Akarken, İ., & Zorbozan, O. (2017). Bir ikinci basamak sağlık merkezinde tam idrar tetkikinin performansının değerlendirilmesi. Türk Klinik Biyokimya Derg, 15(2), 45-51.