A Novel Review: Association of Alzheimer's Disease with the SUMO Protein Family

Beyza Aydin

EN

A Novel Review: Association of Alzheimer's Disease with the SUMO Protein Family

Abstract

Neurodegenerative diseases are disorders characterized by progressive neuron loss, which, in advanced stages, lead to cognitive and motor behavioral abnormalities. These diseases can arise from both internal and external factors such as genetics, aging, nutrition, and stress. Numerous studies have indicated that protein aggregation is a common hallmark of neurodegenerative diseases. Misfolded or improperly expressed proteins significantly impact the progression of these diseases. Recent studies have provided evidence that certain paralogs of SUMO proteins play a significant role in neurodegenerative diseases. This review focuses on Alzheimer's disease, a prominent neurodegenerative condition, and explores the impact of SUMO proteins on this disease. It has been observed that this protein family regulates cellular processes through post-translational modifications, influencing Alzheimer's disease both positively and negatively. Alzheimer's disease is a multifactorial neurodegenerative disorder, and its prevalence is increasing globally with the aging population. From this perspective, investigating the effects of SUMO proteins offers promising insights into potential treatments for these currently incurable diseases.

Keywords

Supporting Institution

There are no Support.

Ethical Statement

There are no ethical conflicts.

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Details

Primary Language

English

Subjects

Neurogenetics

Journal Section

Review Article

Authors

Beyza Aydin ^*
Türkiye

Publication Date

January 31, 2025

Submission Date

June 16, 2024

Acceptance Date

November 17, 2024

Published in Issue

Year 2025 Volume: 2 Number: 1

IZ

https://izlik.org/JA59CZ54KW

Cite

RIS / Bibtex

APA

Aydin, B. (2025). A Novel Review: Association of Alzheimer’s Disease with the SUMO Protein Family. Hitit Journal Of Science, 2(1), 1-8. https://izlik.org/JA59CZ54KW

AMA

1.Aydin B. A Novel Review: Association of Alzheimer’s Disease with the SUMO Protein Family. HJS. 2025;2(1):1-8. https://izlik.org/JA59CZ54KW

Chicago

Aydin, Beyza. 2025. “A Novel Review: Association of Alzheimer’s Disease With the SUMO Protein Family”. Hitit Journal Of Science 2 (1): 1-8. https://izlik.org/JA59CZ54KW.

EndNote

Aydin B (January 1, 2025) A Novel Review: Association of Alzheimer’s Disease with the SUMO Protein Family. Hitit Journal Of Science 2 1 1–8.

IEEE

[1]B. Aydin, “A Novel Review: Association of Alzheimer’s Disease with the SUMO Protein Family”, HJS, vol. 2, no. 1, pp. 1–8, Jan. 2025, [Online]. Available: https://izlik.org/JA59CZ54KW

ISNAD

Aydin, Beyza. “A Novel Review: Association of Alzheimer’s Disease With the SUMO Protein Family”. Hitit Journal Of Science 2/1 (January 1, 2025): 1-8. https://izlik.org/JA59CZ54KW.

JAMA

1.Aydin B. A Novel Review: Association of Alzheimer’s Disease with the SUMO Protein Family. HJS. 2025;2:1–8.

MLA

Aydin, Beyza. “A Novel Review: Association of Alzheimer’s Disease With the SUMO Protein Family”. Hitit Journal Of Science, vol. 2, no. 1, Jan. 2025, pp. 1-8, https://izlik.org/JA59CZ54KW.

Vancouver

1.Beyza Aydin. A Novel Review: Association of Alzheimer’s Disease with the SUMO Protein Family. HJS [Internet]. 2025 Jan. 1;2(1):1-8. Available from: https://izlik.org/JA59CZ54KW