β-Phenylethylamine Dopamine Imine D2 receptor Molecular docking
In this study, new pyridine-based imine compounds (8-10) were synthesized and docking studies of these compounds against D2 Dopamine receptor (6CM4) were performed. The structures of these compounds, which were synthesized using the microwave method, were determined by 1H-NMR, 13C-NMR and elemental analysis techniques. The binding energy values vary range from -6.79 to -7.07 kcal/mol with D2 Dopamine Receptor/PDB: 6MC4. Compound 10 (-7.07 kcal mol-1) showed better binding energy than 9 (-6.95 kcal mol-1) and 8 (-6.79 kcal/mol).
β-Phenylethylamine Dopamine Imine D2 receptor Molecular docking
Birincil Dil | İngilizce |
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Konular | Gıda Teknolojileri |
Bölüm | Research Article |
Yazarlar | |
Yayımlanma Tarihi | 30 Haziran 2023 |
Gönderilme Tarihi | 18 Şubat 2023 |
Yayımlandığı Sayı | Yıl 2023 |
Hittite Journal of Science and Engineering Creative Commons Atıf-GayriTicari 4.0 Uluslararası Lisansı (CC BY NC) ile lisanslanmıştır.