An Investigating on DNA Binding Activity of Zn(II) Phthalocyanine Complex Having Tetra Substituted Phenoxy-3-methoxybenzoic Acid Group

Year 2022, Volume: 9 Issue: 1, 19 - 25, 30.03.2022

Zekeriya Ballı , Mehmet Salih Ağırtaş , Ali Arslantas

https://doi.org/10.17350/HJSE19030000251

Abstract

The tetra substituted Zn(II) phthalocyanine complex having the dicyanophenoxy)-3-methoxybenzoic acid group had been obtained from 4-(3, 4-dicyanophenoxy)-3-methoxybenzoic acid and analyzed with the application of FT-IR, NMR, UV/Vis techniques in compliance with reported literature. The interacting property of Pc4 by CT-DNA was examined with absorption bands, emission titrations, melting temperature, viscosity, and gel electrophoresis procedures. The obtained findings from these techniques demonstrated that the complex containing the dicyanophenoxy)-3-methoxybenzoic acid binds to the DNA by means of intercalation attachment mechanisms.

Keywords

CT-DNA, Zinc phthalocyanine, Absorption specta, Gel electrophoresis

Supporting Institution

This research was supported by the Commission of Scientific Research Project of Karabük University.

Project Number

KBÜBAP-18-DS-046.

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