MİGREN HASTALARINDA PSİKOSOSYAL VE DAVRANIŞSAL FAKTÖRLERİN YORGUNLUKLA İLİŞKİSİ

Abstract

Keywords

• Migren
• yorgunluk
• psikososyal faktör
• davranışsal faktör
• biopsikososyal

The Relationship Between Psychosocial and Behavioral Factors and Fatigue in Migraine Patients

Abstract

Purpose: Migraine is a neurological disorder characterized by recurrent headaches often accompanied by fatigue. Fatigue is one of the most disabling symptoms experienced by migraine patients, yet it remains underexplored. This study examined the relationship between fatigue and psychosocial and behavioral factors in migraine patients. Method: This cross-sectional study included patients aged 18–55 years who were diagnosed with migraine. The Migraine Disability Assessment Questionnaire (MIDAS) was used to assess migraine-related disability, and the Modified Fatigue Impact Scale (MFIS) was used to assess fatigue. Psychosocial factors were evaluated using the Beck Depression Inventory (BDI) for depressive mood, the Pain Catastrophizing Scale (PCS) for pain-related catastrophizing, and the General Self-Efficacy Scale (GSE) for self-efficacy. Behavioral factors were assessed using the Epworth Sleepiness Scale (ESS) and the Pittsburgh Sleep Quality Index (PSQI) for sleep patterns, the Motivation for Healthy Eating Scale (MHES) for nutritional attitude, and the 36- Item Self-Reported Physical Activity Behavior (SPAB) questionnaire for physical activity levels. Results: There were moderate correlations between fatigue (MFIS) and depressive mood, pain catastrophizing, self-efficacy, and sleep quality (ρ = 0.318, 0.371, 0.371, and 0.403, respectively). Conclusion: Fatigue in migraine patients appears to be closely associated with psychosocial and behavioral factors, emphasizing the importance of a holistic, biopsychosocial approach in clinical management. Fatigue in migraine patients is related to psychosocial and behavioral factors, including depressive mood, pain catastrophizing, self-efficacy, and sleep quality, all of which should be evaluated for appropriate management.

Keywords

• psychosocial factor
• behavioral factor
• Migraine
• fatigue
• biopsychosocial

References

1. 1. Seo J-G, Park S-P. Significance of fatigue in patients with migraine. Journal of Clinical Neuroscience. 2018;50:69-73.
2. 2. Cosci F, Svicher A, Mansueto G, Benemei S, Chiarugi A, De Cesaris F, et al. Mental pain and pain-proneness in patients with migraine: results from the PAINMIG cohort-study. CNS Spectr. 2021;26(5):491-500.
3. 3. Lucchesi C, Baldacci F, Cafalli M, Dini E, Giampietri L, Siciliano G, et al. Fatigue, sleep-wake pattern, depressive and anxiety symptoms and body-mass index: analysis in a sample of episodic and chronic migraine patients. Neurol Sci. 2016;37(6):987-9.
4. 4. Wang Y, Wang Y, Yue G, Zhao Y. Energy metabolism disturbance in migraine: From a mitochondrial point of view. Front Physiol. 2023;14:1133528.
5. 5. Lucchesi C, Baldacci F, Cafalli M, Dini E, Siciliano G, Bonuccelli U, et al. P041. Analysis of body mass index, psychiatric comorbidity, sleep-wake pattern and occurrence of fatigue in episodic and chronic migraine patients. J Headache Pain. 2015;16(Suppl 1):A188.
6. 6. Raggi A, Giovannetti AM, Quintas R, D'Amico D, Cieza A, Sabariego C, et al. A systematic review of the psychosocial difficulties relevant to patients with migraine. J Headache Pain. 2012;13(8):595-606.
7. 7. Dawson D, Chapman J, Thomas MJ. Fatigue-proofing: a new approach to reducing fatigue-related risk using the principles of error management. Sleep medicine reviews. 2012;16(2):167-75.
8. 8. Dukes JC, Chakan M, Mills A, Marcaurd M. Approach to Fatigue: Best Practice. Med Clin North Am. 2021;105(1):137-48.

9. 9. Karsan N, Goadsby PJ. Migraine Is More Than Just Headache: Is the Link to Chronic Fatigue and Mood Disorders Simply Due to Shared Biological Systems? Front Hum Neurosci. 2021;15:646692.
10. 10. Peres MF, Zukerman E, Young WB, Silberstein SD. Fatigue in chronic migraine patients. Cephalalgia. 2002;22(9):720-4.
11. 11. Seo JG, Park SP. Significance of fatigue in patients with migraine. J Clin Neurosci. 2018;50:69-73.
12. 12. Delva M, Delva I, Pinchuk V, Kryvchun A, Purdenko T. Prevalence and predictors of fatigue in patients with episodic migraine. Wiad Lek. 2022;75(8 pt 2):1970-4.
13. 13. Carmack CL, Basen-Engquist K, Gritz ER. Survivors at higher risk for adverse late outcomes due to psychosocial and behavioral risk factors. Cancer Epidemiol Biomarkers Prev. 2011;20(10):2068-77.
14. 14. Buell JC, Eliot RS. Psychosocial and behavioral influences in the pathogenesis of acquired cardiovascular disease. Am Heart J. 1980;100(5):723-40.
15. 15. Martelletti P, Steiner TJ. Handbook of headache: practical management: Springer Science & Business Media; 2011.
16. 16. Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1-211.
17. 17. Lipton RB, Serrano D, Holland S, Fanning KM, Reed ML, Buse DC. Barriers to the diagnosis and treatment of migraine: effects of sex, income, and headache features. Headache. 2013;53(1):81-92.
18. 18. Ertaş M, Siva A, Dalkara T, Uzuner N, Dora B, Inan L, et al. Validity and reliability of the Turkish Migraine Disability Assessment (MIDAS) questionnaire. Headache. 2004;44(8):786-93.
19. 19. Learmonth YC, Dlugonski D, Pilutti LA, Sandroff BM, Klaren R, Motl RW. Psychometric properties of the Fatigue Severity Scale and the Modified Fatigue Impact Scale. J Neurol Sci. 2013;331(1-2):102-7.
20. 20. Hisli N. Beck depresyon envanterinin universite ogrencileri icin gecerliligi, guvenilirligi.(A reliability and validity study of Beck Depression Inventory in a university student sample). J Psychol. 1989;7:3-13.
21. 21. Süren M, Okan I, Gökbakan AM, Kaya Z, Erkorkmaz Ü, Arici S, et al. Factors associated with the pain catastrophizing scale and validation in a sample of the Turkish population. Turkish journal of medical sciences. 2014;44(1):104-8.
22. 22. Yıldırım F, İlhan İÖ. Genel öz yeterlilik ölçeği türkçe formunun geçerlilik ve güvenilirlik çalışması. Türk Psikiyatri Dergisi. 2010;21(4):301-8.
23. 23. Izci B, Ardic S, Firat H, Sahin A, Altinors M, Karacan I. Reliability and validity studies of the Turkish version of the Epworth Sleepiness Scale. Sleep Breath. 2008;12(2):161-8.
24. 24. Ağargün M, Kara H, Anlar O. Pittsburgh uyku kalitesi indeksinin geçerliği ve güvenirliği. Türk Psikiyatri Dergisi. 1996;7(2):107-15.
25. 25. Akar UDG, Öztürk M, Kl N. Migrenli kadınlarda depresyon, uyku bozukluğu ve seksüel disfonksiyon. Int J Prev Med. 2014;5(9):1113-8.
26. 26. Demir GT, Cicioğlu Hİ. Sağlıklı beslenmeye ilişkin tutum ölçeği (sbitö): geçerlik ve güvenirlik çalışması. Gaziantep Üniversitesi Spor Bilimleri Dergisi. 2019;4(2):256-74.
27. 27. İncedayı S. Planlı Davranış Kuramı’na Göre Geliştirilen Fiziksel Aktivite Ölçeğini Türk Toplumuna Uyarlama Çalışması [Yüksek Lisans Tezi]: Ege Üniversitesi; 2005.
28. 28. Chan Y. Biostatistics 104: correlational analysis. Singapore Med J. 2003;44(12):614-9.
29. 29. Akoglu H. User's guide to correlation coefficients. Turkish journal of emergency medicine. 2018;18(3):91-3.
30. 30. Pistoia F, Salfi F, Saporito G, Ornello R, Frattale I, D'Aurizio G, et al. Behavioral and psychological factors in individuals with migraine without psychiatric comorbidities. J Headache Pain. 2022;23(1):110.
31. 31. Seidel S, Hartl T, Weber M, Matterey S, Paul A, Riederer F, et al. Quality of sleep, fatigue and daytime sleepiness in migraine - a controlled study. Cephalalgia. 2009;29(6):662-9.
32. 32. Servaes P, van der Werf S, Prins J, Verhagen S, Bleijenberg G. Fatigue in disease-free cancer patients compared with fatigue in patients with chronic fatigue syndrome. Support Care Cancer. 2001;9(1):11-7.
33. 33. Bakshi R, Shaikh ZA, Miletich RS, Czarnecki D, Dmochowski J, Henschel K, et al. Fatigue in multiple sclerosis and its relationship to depression and neurologic disability. Mult Scler. 2000;6(3):181-5.
34. 34. Skorvanek M, Gdovinova Z, Rosenberger J, Saeedian RG, Nagyova I, Groothoff JW, et al. The associations between fatigue, apathy, and depression in Parkinson's disease. Acta Neurol Scand. 2015;131(2):80-7.
35. 35. Domingues RB, Costa EA, Silva A, Jr., Domingues SA, Leal JC, Gomez RS, et al. Correlation between migraine subtypes and depression. Arq Neuropsiquiatr. 2008;66(3a):485-7.
36. 36. Fuller-Thomson E, Schrumm M, Brennenstuhl S. Migraine and Despair: Factors Associated with Depression and Suicidal Ideation among Canadian Migraineurs in a Population-Based Study. Depress Res Treat. 2013;2013:401487.
37. 37. Mercante JP, Peres MF, Guendler V, Zukerman E, Bernik MA. Depression in chronic migraine: severity and clinical features. Arq Neuropsiquiatr. 2005;63(2a):217-20.
38. 38. Gil-Martínez A, Grande-Alonso M, La Touche R, Lara-Lara M, López-López A, Fernández-Carnero J. Psychosocial and Somatosensory Factors in Women with Chronic Migraine and Painful Temporomandibular Disorders. Pain Res Manag. 2016;2016:3945673.
39. 39. Kim S, Bae DW, Park SG, Park JW. The impact of Pain-related emotions on migraine. Sci Rep. 2021;11(1):577.
40. 40. Rashid-Tavalai Z, Bakhshani NM, Amirifard H, Lashkaripour M. Effectiveness of Combined Copying Skills Training and Pharmacological Therapy for Patients with Migraine. Glob J Health Sci. 2015;8(6):179-86.
41. 41. Boosman H, Visser-Meily JM, Meijer JW, Elsinga A, Post MW. Evaluation of change in fatigue, self-efficacy and health-related quality of life, after a group educational intervention programme for persons with neuromuscular diseases or multiple sclerosis: a pilot study. Disabil Rehabil. 2011;33(8):690-6.
42. 42. Milrad SF, Hall DL, Jutagir DR, Lattie EG, Czaja SJ, Perdomo DM, et al. Relationship satisfaction, communication self-efficacy, and chronic fatigue syndrome-related fatigue. Soc Sci Med. 2019;237:112392.
43. 43. Stronks DL, Tulen JH, Bussmann JB, Mulder LJ, Passchier J. Interictal daily functioning in migraine. Cephalalgia. 2004;24(4):271-9.
44. 44. Peres MF, Stiles MA, Siow HC, Silberstein SD. Excessive daytime sleepiness in migraine patients. J Neurol Neurosurg Psychiatry. 2005;76(10):1467-8.
45. 45. Spierings EL, van Hoof MJ. Fatigue and sleep in chronic headache sufferers: an age- and sex-controlled questionnaire study. Headache. 1997;37(9):549-52.
46. 46. Bakırhan H, Yıldıran H, Uyar Cankay T. Associations between diet quality, DASH and Mediterranean dietary patterns and migraine characteristics. Nutr Neurosci. 2021:1-11.