Metabolik Sendromlu Bireylerde Solunum Kas Fonksiyonları ile Bilişsel Fonksiyonlar Arasındaki İlişki

Abstract

Amaç Metabolik sendromlu (MetS) bireylerde bilişsel bozulma genellikle kardiyovasküler ve metabolik mekanizmalara atfedilmektedir. Ancak solunum kas performansı ile bilişsel fonksiyon arasındaki ilişki henüz net değildir. Bu çalışmanın amacı, MetS’li bireylerde bilişsel fonksiyon ile solunum kas fonksiyonları, periferik kas kuvveti ve fiziksel aktivite (FA) düzeyleri arasındaki ilişkileri araştırmaktır. Yöntem Bu kesitsel çalışmaya MetS’li 50 birey (ortalama yaş: 51.68 ± 5.17 yıl) katıldı. Bilişsel fonksiyon Standardize Mini-Mental Test (SMMT) kullanılarak değerlendirildi. Solunum kas kuvveti maksimal inspiratuvar basınç (MIP) ve maksimal ekspiratuvar basınç (MEP) ile, solunum kas enduransı ise sabit iş yükü testi ile değerlendirildi. Periferik kas kuvveti el kavrama kuvveti(HGS) ve kuadriseps kas kuvveti(QMS) ile, FA düzeyi ise Uluslararası Fiziksel Aktivite Anketi kısa formu (IPAQ-SF) kullanılarak değerlendirildi. Bulgular Toplam SMMT skoru ile MIP (r=0.398, p=0.008), MEP (r=0.420, p=0.005), solunum kas enduransı (r=0.414, p=0.008), HGS (r=0.456, p=0.002) ve QMS (r=0.397, p=0.008) arasında anlamlı düzeyde orta derecede pozitif korelasyon bulundu. Dikkat alt skoru tüm solunum ve periferik kas parametreleri ile anlamlı olarak koreleydi (p<0.05). Özellikle solunum kas enduransı, SMMT-oryantasyon (r=0.402, p=0.010) ve dil (r=0.343, p=0.030) skorları ile ilişkili olan tek parametreydi. Tüm katılımcılar toplam IPAQ-SF skoruna göre fiziksel olarak inaktif olarak sınıflandırıldı. Sonuç MetS’li bireylerde bilişsel fonksiyon, solunum kas performansı ve periferik kas kuvveti ile ilişkilidir. Bu bulgular, solunum kas performansının bilişsel sağlık için fizyolojik bir belirteç olarak hizmet edebileceğini düşündürmektedir. Solunum kas eğitimi ve FA’nın artırılmasının multidisipliner rehabilitasyon programlarına dahil edilmesi, MetS’li bireylerde bilişsel fonksiyonun korunmasına ve iyileştirilmesine yardımcı olabilir.

Keywords

• metabolik sendrom
• kognitif fonksiyon
• solunum kas kuvveti
• solunum kas enduransı

The Relationship Between Cognitive Function, Respiratory Muscle Performance, and Peripheral Muscle Strength in Physically Inactive Individuals with Metabolic Syndrome

Abstract

Purpose: Metabolic syndrome (MetS) is associated with impairments in multiple cognitive domains, particularly attention, executive function, and memory; however, the potential contribution of respiratory muscle performance and peripheral muscle strength to cognitive function in this population remains insufficiently explored. Therefore, this study aimed to investigate the relationships between cognitive function, respiratory muscle performance, and peripheral muscle strength in physically inactive individuals with MetS. Method: This cross-sectional study included 50 individuals with MetS recruited from the Department of Internal Medicine at Hacettepe University. Cognitive function was assessed using the Standardized Mini-Mental Test (SMMT). Respiratory muscle strength was evaluated by measuring maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP), while respiratory muscle endurance was assessed using a constant-load test. Peripheral muscle strength was determined using handgrip and quadriceps muscle strength measurements. Physical activity level was assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF), and all participants were classified as physically inactive. Results: The total SMMT score showed significant positive correlations with MIP (r=0.398, p=0.008), MEP (r=0.420, p=0.005), respiratory muscle endurance (r=0.414, p=0.008), handgrip strength (r=0.456, p=0.002), and quadriceps muscle strength (r=0.397, p=0.008). The attention subscore was significantly correlated with all respiratory and peripheral muscle parameters (p<0.05). Respiratory muscle endurance was also correlated with orientation (r=0.402, p=0.010) and language (r=0.343, p=0.030) scores. Discussion: Cognitive function in physically inactive individuals with MetS was associated with respiratory muscle performance and peripheral muscle strength. These findings suggest that respiratory muscle performance may be related to cognitive health in this population. Multidisciplinary rehabilitation approaches, including respiratory muscle training and physical activity promotion, may help support cognitive function.

Keywords

• Cognition
• Metabolic Syndrome
• Muscle Strength
• Physical Activity
• Respiratory Muscles

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