Antimicrobial Activity of Grapefruit Seed

Abstract

Citrus paradisi Macfad. (Rutaceae), evergreen tree originally of Asiatic South West, is

also known as grapefruit. The fruit is known as an effective pharmacological remedy

and is used to prepare different cosmetic products. The aim of this study was to investigate

the antimicrobial activity of aqueous and ethanolic grapefruit seed extracts and

also glycerol solution of grapefruit seed against some bacteria and yeast. Disc diffusion

method was used to determine the antimicrobial activity. Depending on the results,

none of the grapefruit seed samples showed antimicrobial activity against all tested

microorganisms. Although the antimicrobial activity of grapefruit seed has been reported

in many publications, this difference may be due to the variation in the contents of

polyphenols, especially flavonoids.

Keywords

• Citrus paradisi,grapefruit seed

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