Pharmacovigilance Activities in the Treatment of COVID-19

Yıl 2021, Cilt: 41 Sayı: 2, 93 - 101, 01.06.2021

Gizem Özal Bilge İnceoğlu Sezen Süzgeç Nur Hilal Duran Gizem Topaloğlu Burcu Arda Ali Gulhan

https://doi.org/10.52794/hujpharm.903721

Öz

The unexpected pandemic initiated by the new coronavirus 2019 (2019-nCoV) caused severe panic among people around the world since December 2019. Coronavirus disease 2019 (COVID-19) has wreaked havoc, and Health Authorities have started to make announcements and studies have been started quickly, for effective treatment and vaccination. In studies, drugs that reduce the symptoms of COVID-19 and alleviate the course of the disease have been used. In addition to the effects of these promising drugs, adverse events and multiple drug interactions have begun to appear all over the world, as well as in our country. Therefore, pharmacovigilance is of particular importance during the COVID-19 pandemic. Health authorities have been taking additional actions and measures in order to carry out adverse effects monitoring and risk minimization activities of drugs. In our study, we have reviewed the measures taken related to COVID-19 in Turkey and around the world along with safety of drugs used to treat COVID-19 and pharmacovigilance activities during the pandemic.

Anahtar Kelimeler

SARS-CoV-2, COVID-19, Pharmacovigilance, Drug Safety, Adverse Event

Destekleyen Kurum

N/A

Proje Numarası

N/A

Teşekkür

N/A

COVID-19 Tedavisinde Farmakovijilans Aktiviteleri

Öz

Aralık 2019’dan bu yana yeni tip koronavirüsün (2019-nCoV) başlattığı beklenmedik pandemi, dünyanın dört bir yanındaki insanlar arasında şiddetli paniğe neden olmuştur. Koronavirüs hastalığı 2019 (COVID-19) ciddi hasarlara yol açmış ve Sağlık otoriteleri tarafından yayınlanan duyurular ile etkili tedavi ve aşı için çalışmalara hızlıca başlanmıştır. Çalışmalarda, COVID-19 semptomlarını azaltıcı ve hastalığın seyrini hafifletici ilaçlar kulanılmaya başlanmıştır. Umut vadeden bu ilaçların etkilerinin yanısıra, tüm dünyada ve ülkemizde advers olaylar ve çoklu ilaç etkileşimleri görülmeye başlanmıştır. Bu nedenle, COVID-19 pandemi sürecinde farmakovijilans ayrı bir önem arz etmektedir. İlaçların advers etkilerinin takibi ve risk minimizasyon faaliyetlerini yürütmek açısından sağlık otoriteleri ek aksiyonlar ve önlemler almaktadır. Çalışmamızın amacı, Türkiye'de ve dünyada COVID-19 ile ilgili alınan önlemler ile birlikte, COVID-19 tedavisinde kullanılan ilaçların güvenliliği ve pandemi sürecindeki farmakovijilans aktivitelerini derlemektir.

Anahtar Kelimeler

SARS-CoV-2, COVID-19, Farmakovijilans, İlaç Güvenliliği, Advers Olay

Proje Numarası

N/A

Kaynakça

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