High c-peptide level: marker of mortality in type 2 diabetes mellitus patients

Abstract

Objective: We aimed to retrospectively investigate the effect of c-peptide level on mortality in patients with Type 2 Diabetes Mellitus.
Methods: Patients who applied to the Dicle University Medical Faculty in 2012 were screened in the database and included a 1000 DM patient with c-peptide, after 5 years the patients were re-evaluated. The patients were then categorized. The patients were divided into two groups, dead patients and living patients. Two groups of c-peptide levels were compared.
Results: Totally 1000 patients included in the study. 392 (39.2%) of the patients were male and 608 (60.8%) were female, the mean age was 57. Patients were divided into two groups: the patient group who died and the patient group who was living. The number of patients died was 146 (14.6%) and the number of living patients was 844 (75.4%). C-peptide levels were found to be higher in patients who died (3,5 ± 2,7 ng / ml) than those who survived (2,9 ± 1,7 ng / ml) and statistically significant (p<0.05).
Conclusion: The high c-peptide levels in patients with Diabetes Mellitus, it may be an important parameter to predict mortality.

Keywords

• Diabetes mellitus,c-peptide

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