Yıl 2015, Cilt 7 , Sayı 2, Sayfalar 12 - 22 2015-12-01

What is the most effective antioxidant against ulcers? An experimental study

İskender KAPLANOGLU [1] , Yusuf NERGİZ [2] , Selcuk TUNİK [3] , Mustafa Agah TEKİNDAL [4] , Murat AKKUS [5]


Background: The aim of this study was to evaluate the effects of selenium, gingko biloba, melatonin and vitamin E, which are antioxidants in the prevention of ulcerative lesions occurring in rats exposed to immobility and cold stress by using comparative histochemical and statistical methods. Material and Methods: 6 groups were created with 42 Wistar albino rats; control, ulcer (performed by immobilization and cold stress), selenium (0.5 ml/kg), Gingko biloba (300 mg/kg), melatonin (60 mg/kg), vitamin E (60 mg/kg). Gastric tissues were taken and examined by histochemical methods. Statistical methods were used to determined gastric pit and glands leight. Results: In the ulcer group; expansive degenerative changes was seen in gastric mucosa and lots of different types necrotic areas were seen. In the vitamin E administered group, similar findings with the control group were observed except the superficial mucosal epithelium spilth in the located area and moderate dilatation in gastric glands. With the alcian blue dying to observe the mucus compared with other groups, the most evident increase in mucus was found in this group. Conclusions: In the histochemical and statistical evaluations we considered that prevention of the formation the gastric lesions in case of stress, vitamin E was the most effective agent
Gastric ulcer, Gingko biloba, selenium, melatonin, vitamin E, rat
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Diğer ID JA34ZG58RZ
Bölüm Araştırma
Yazarlar

Yazar: İskender KAPLANOGLU

Yazar: Yusuf NERGİZ

Yazar: Selcuk TUNİK

Yazar: Mustafa Agah TEKİNDAL

Yazar: Murat AKKUS

Tarihler

Yayımlanma Tarihi : 1 Aralık 2015

Bibtex @ { iamr272716, journal = {International Archives of Medical Research}, issn = {2146-6033}, address = {Dicle Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji AD, 21280, Diyarbakır-Türkiye}, publisher = {Veysi AKPOLAT}, year = {2015}, volume = {7}, pages = {12 - 22}, doi = {}, title = {What is the most effective antioxidant against ulcers? An experimental study}, key = {cite}, author = {KAPLANOGLU, İskender and NERGİZ, Yusuf and TUNİK, Selcuk and TEKİNDAL, Mustafa Agah and AKKUS, Murat} }
APA KAPLANOGLU, İ , NERGİZ, Y , TUNİK, S , TEKİNDAL, M , AKKUS, M . (2015). What is the most effective antioxidant against ulcers? An experimental study. International Archives of Medical Research , 7 (2) , 12-22 . Retrieved from https://dergipark.org.tr/tr/pub/iamr/issue/25888/272716
MLA KAPLANOGLU, İ , NERGİZ, Y , TUNİK, S , TEKİNDAL, M , AKKUS, M . "What is the most effective antioxidant against ulcers? An experimental study". International Archives of Medical Research 7 (2015 ): 12-22 <https://dergipark.org.tr/tr/pub/iamr/issue/25888/272716>
Chicago KAPLANOGLU, İ , NERGİZ, Y , TUNİK, S , TEKİNDAL, M , AKKUS, M . "What is the most effective antioxidant against ulcers? An experimental study". International Archives of Medical Research 7 (2015 ): 12-22
RIS TY - JOUR T1 - What is the most effective antioxidant against ulcers? An experimental study AU - İskender KAPLANOGLU , Yusuf NERGİZ , Selcuk TUNİK , Mustafa Agah TEKİNDAL , Murat AKKUS Y1 - 2015 PY - 2015 N1 - DO - T2 - International Archives of Medical Research JF - Journal JO - JOR SP - 12 EP - 22 VL - 7 IS - 2 SN - 2146-6033- M3 - UR - Y2 - 2020 ER -
EndNote %0 International Archives of Medical Research What is the most effective antioxidant against ulcers? An experimental study %A İskender KAPLANOGLU , Yusuf NERGİZ , Selcuk TUNİK , Mustafa Agah TEKİNDAL , Murat AKKUS %T What is the most effective antioxidant against ulcers? An experimental study %D 2015 %J International Archives of Medical Research %P 2146-6033- %V 7 %N 2 %R %U
ISNAD KAPLANOGLU, İskender , NERGİZ, Yusuf , TUNİK, Selcuk , TEKİNDAL, Mustafa Agah , AKKUS, Murat . "What is the most effective antioxidant against ulcers? An experimental study". International Archives of Medical Research 7 / 2 (Aralık 2015): 12-22 .
AMA KAPLANOGLU İ , NERGİZ Y , TUNİK S , TEKİNDAL M , AKKUS M . What is the most effective antioxidant against ulcers? An experimental study. IAMR. 2015; 7(2): 12-22.
Vancouver KAPLANOGLU İ , NERGİZ Y , TUNİK S , TEKİNDAL M , AKKUS M . What is the most effective antioxidant against ulcers? An experimental study. International Archives of Medical Research. 2015; 7(2): 22-12.