igusabder

İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi

2536-4499 2602-2605

İstanbul Gelişim Üniversitesi

10.38079/igusabder.1627062

Nutritional Science Clinical Nutrition

Beslenme Bilimi Klinik Beslenme

Association of Diet Quality and Sleep Duration with IgG Levels and Serum Lipids in Two-Dose COVID-19 Vaccinated Volunteers

İki Doz COVID-19 Aşısı Yapılan Gönüllülerde Diyet Kalitesi ve Uyku Süresinin IgG Düzeyleri ve Serum Lipidleri ile İlişkisi

https://orcid.org/0000-0003-2062-098X

Cesur

Fatih

EGE UNIVERSITY

04 29 2026

28 208 225 01 25 2025 03 11 2026

2017

İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi

Aim: This study aimed to investigate the associations of sleep duration, diet quality, and body fat classification with IgG levels, biochemical parameters, and anthropometric measurements in volunteers who received two doses of the COVID-19 vaccine.Method: A total of 61 volunteers participated in the study. Biomarkers, anthropometric measurements, physical activity, sleep duration, and serum IgG levels were assessed. Dietary Quality Index-2015 (DQI-2015) and nutrient intake were calculated using the CeviCal program based on food frequency data.Results: Individuals with short sleep duration had significantly higher fasting blood sugar levels compared to those with normal sleep duration (p<0.05). Individuals with long sleep duration had higher serum IgG levels compared to those with normal sleep duration (p=0.029). LDL cholesterol levels were lower in individuals who consumed alcohol, while T3 levels were lower in smokers (p<0.05). Total cholesterol, non-HDL cholesterol, and waist circumference values were higher in individuals with poor diet quality (p<0.05). Total cholesterol and triglyceride levels were found to be higher in obese individuals (p<0.05). The increase in IgG levels was found to be associated with an increase in fasting serum glucose levels, and a moderate positive correlation was found between these parameters (p<0.001, r=0.445). IgG levels were significantly lower in individuals with high daily vitamin C intake (p=0.037). 25(OH)D levels were lower in individuals with active physical activity levels compared to inactive individuals (p<0.05).Conclusion: Short sleep duration, poor diet quality, and obesity have been associated with adverse changes in glucose, lipid profile, and anthropometric measurements. Long sleep duration has been associated with higher IgG levels, while high vitamin C intake has been associated with lower IgG levels. Additionally, increased IgG levels have been associated with higher glucose levels. Larger sample studies are needed to confirm these findings.

Amaç: Bu çalışma, iki doz COVID-19 aşısı alan gönüllülerde uyku süresi, beslenme kalitesi ve vücut yağ sınıflandırması ile IgG düzeyleri, biyokimyasal parametreler ve antropometrik ölçümler arasındaki ilişkileri araştırmayı amaçlamıştır.Yöntem: Çalışmaya toplam 61 gönüllü katılmıştır. Biyobelirteçler, antropometrik ölçümler, fiziksel aktivite, uyku süresi ve serum IgG seviyeleri değerlendirilmiştir. Besin tüketim sıklıkları kullanılarak CeviCal programı aracılığıyla Diyet Kalite İndeksi-2015 (DQI-2015) ve besin öğeleri hesaplanmıştır.Bulgular: Kısa uyku süresine sahip bireylerin açlık kan şekeri seviyeleri, normal uyuyanlara kıyasla anlamlı derecede daha yüksek bulunmuştur (p<0,05). Uzun uyku süresine sahip bireylerin serum IgG seviyeleri, normal uyuyanlara kıyasla daha yüksek tespit edilmiştir (p=0,029). Alkol kullanan bireylerde LDL kolesterol düzeyleri daha düşük, sigara içenlerde ise T3 düzeyleri daha düşük bulunmuştur (p<0,05). Diyet kalitesi düşük bireylerde toplam kolesterol, non-HDL kolesterol ve bel çevresi değerleri daha yüksek bulunmuştur (p<0,05). Obez bireylerde toplam kolesterol ve trigliserit düzeyleri daha yüksek tespit edilmiştir (p<0,05). IgG seviyelerindeki artış, açlık serum glukoz seviyelerinde artış ile ilişkili bulunmuş ve bu parametreler arasında orta düzeyde pozitif korelasyon saptanmıştır (p<0,001, r=0,445). Günlük C vitamini alımı yüksek olan bireylerin IgG seviyeleri anlamlı şekilde daha düşük bulunmuştur (p=0,037). Aktif fiziksel aktivite düzeyine sahip bireylerde, pasif bireylere kıyasla 25(OH)D düzeyleri daha düşük bulunmuştur (p<0,05).Sonuç: Kısa uyku süresi, düşük diyet kalitesi ve obezite; glukoz, lipid profili ve antropometrik ölçümlerde olumsuz değişiklikler ile ilişkilendirilmiştir. Uzun uyku süresi daha yüksek IgG düzeyleri ile ilişkili bulunurken, yüksek C vitamini alımı daha düşük IgG düzeyleri ile ilişkilendirilmiştir. Ayrıca, artmış IgG düzeyleri daha yüksek glukoz seviyeleri ile ilişkili bulunmuştur. Bulguların doğrulanması için daha geniş örneklemli çalışmalara ihtiyaç vardır.

Diet quality COVID-19 vaccine serum IgG sleep duration.

Diyet kalitesi COVID-19 aşısı serum IgG uyku süresi.

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