A new approach to breast cancer therapy: targeted nanocarrier systems

Nazan Gökşen Tosun; Özlem Kaplan; Seçil Erden Tayhan; Cemil Alkan; İsa Gökçe

doi:10.32571/ijct.1139627

Derleme

A new approach to breast cancer therapy: targeted nanocarrier systems

Yıl 2022, Cilt: 6 Sayı: 2, 81 - 92, 31.12.2022

Nazan Gökşen Tosun , Özlem Kaplan , Seçil Erden Tayhan , Cemil Alkan , İsa Gökçe

https://doi.org/10.32571/ijct.1139627

Cited By: 2

Öz

Cancer is one of the most prevalent diseases in the world. Breast cancer is the second most deadly cancer type after lung cancer. Surgical intervention, chemotherapy and radiotherapy are the most used conventional methods in the treatment of breast cancer. The non-targeted approach of conventional treatments causes serious side effects in healthy cells and tissues, and often mortality is due to the side effects of these conventional treatments. In recent years, nano-sized particles called drug delivery systems targeting cancer cells have attracted attention as a new approach in cancer treatment. The fact that these nanocarrier systems target tumor cells without damaging healthy tissues has been a hope for breast cancer. Moreover, nanocarriers are unique biomaterials that may exhibit low toxicity, high biocompatibility, biodegradability, ease of use, high dose drug loading, and adjustable surface functionalities. In the present study, we summarize recent studies of nanocarriers that offer a critical review of an alternative strategy to breast cancer therapy.

Anahtar Kelimeler

Breast cancer, Drug delivery systems, Nanocarriers, Nanoparticles

Kaynakça

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Meme kanseri tedavisinde yeni bir yaklaşım: hedefledirilmiş nanotaşıyıcı sistemler

Yıl 2022, Cilt: 6 Sayı: 2, 81 - 92, 31.12.2022

Nazan Gökşen Tosun , Özlem Kaplan , Seçil Erden Tayhan , Cemil Alkan , İsa Gökçe

https://doi.org/10.32571/ijct.1139627

Cited By: 2

Öz

Kanser, dünyadaki en yaygın hastalıklardan biridir. Meme kanseri, akciğer kanserinden sonra ikinci en ölümcül kanser türüdür. Cerrahi müdahale, kemoterapi ve radyoterapi meme kanseri tedavisinde en çok kullanılan geleneksel yöntemlerdir. Konvansiyonel tedavilerin hedefe yönelik olmayan yaklaşımı, sağlıklı hücrelerde ve dokularda ciddi yan etkilere neden olur ve mortalite genellikle bu geleneksel tedavilerin yan etkilerinden dolayı gerçekleşmektedir. Son yıllarda kanser hücrelerini hedef alan ilaç taşıyıcı sistemler adı verilen nano boyutlu partiküller kanser tedavisinde yeni bir yaklaşım olarak dikkatleri üzerine çekmektedir. Bu nanotaşıyıcı sistemlerin sağlıklı dokulara zarar vermeden tümör hücrelerini hedef alması meme kanseri tedavisi için umut verici bir yaklaşımdır. Ayrıca nanotaşıyıcılar, düşük toksisite, yüksek biyouyumluluk, biyobozunurluk, kullanım kolaylığı, yüksek doz ilaç yükleme ve ayarlanabilir yüzey işlevleri gösterebilen benzersiz biyomalzemelerdir. Bu çalışmada, meme kanseri tedavisine alternatif bir yaklaşım sunan nanotaşıyıcıların son çalışmalarını eleştirel bir analizle özetledik.

Anahtar Kelimeler

Meme kanseri, İlaç taşıyıcı sistemler, Nanotaşıyıcılar, Nanopartiküller

Kaynakça

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Toplam 129 adet kaynakça vardır.

Ayrıntılar

Birincil Dil	İngilizce
Konular	Yapısal Biyoloji , Kimya Mühendisliği, Malzeme Üretim Teknolojileri
Bölüm	Review Articles
Yazarlar	Nazan Gökşen Tosun 0000-0001-5269-1067 Özlem Kaplan 0000-0002-3052-4556 Seçil Erden Tayhan 0000-0001-8473-5896 Cemil Alkan 0000-0002-1509-4789 İsa Gökçe 0000-0002-5023-9947
Yayımlanma Tarihi	31 Aralık 2022
Yayımlandığı Sayı	Yıl 2022 Cilt: 6 Sayı: 2

Kaynak Göster

APA	Gökşen Tosun, N., Kaplan, Ö., Erden Tayhan, S., Alkan, C., vd. (2022). A new approach to breast cancer therapy: targeted nanocarrier systems. International Journal of Chemistry and Technology, 6(2), 81-92. https://doi.org/10.32571/ijct.1139627
AMA	Gökşen Tosun N, Kaplan Ö, Erden Tayhan S, Alkan C, Gökçe İ. A new approach to breast cancer therapy: targeted nanocarrier systems. Int. J. Chem. Technol. Aralık 2022;6(2):81-92. doi:10.32571/ijct.1139627
Chicago	Gökşen Tosun, Nazan, Özlem Kaplan, Seçil Erden Tayhan, Cemil Alkan, ve İsa Gökçe. “A New Approach to Breast Cancer Therapy: Targeted Nanocarrier Systems”. International Journal of Chemistry and Technology 6, sy. 2 (Aralık 2022): 81-92. https://doi.org/10.32571/ijct.1139627.
EndNote	Gökşen Tosun N, Kaplan Ö, Erden Tayhan S, Alkan C, Gökçe İ (01 Aralık 2022) A new approach to breast cancer therapy: targeted nanocarrier systems. International Journal of Chemistry and Technology 6 2 81–92.
IEEE	N. Gökşen Tosun, Ö. Kaplan, S. Erden Tayhan, C. Alkan, ve İ. Gökçe, “A new approach to breast cancer therapy: targeted nanocarrier systems”, Int. J. Chem. Technol., c. 6, sy. 2, ss. 81–92, 2022, doi: 10.32571/ijct.1139627.
ISNAD	Gökşen Tosun, Nazan vd. “A New Approach to Breast Cancer Therapy: Targeted Nanocarrier Systems”. International Journal of Chemistry and Technology 6/2 (Aralık 2022), 81-92. https://doi.org/10.32571/ijct.1139627.
JAMA	Gökşen Tosun N, Kaplan Ö, Erden Tayhan S, Alkan C, Gökçe İ. A new approach to breast cancer therapy: targeted nanocarrier systems. Int. J. Chem. Technol. 2022;6:81–92.
MLA	Gökşen Tosun, Nazan vd. “A New Approach to Breast Cancer Therapy: Targeted Nanocarrier Systems”. International Journal of Chemistry and Technology, c. 6, sy. 2, 2022, ss. 81-92, doi:10.32571/ijct.1139627.
Vancouver	Gökşen Tosun N, Kaplan Ö, Erden Tayhan S, Alkan C, Gökçe İ. A new approach to breast cancer therapy: targeted nanocarrier systems. Int. J. Chem. Technol. 2022;6(2):81-92.

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