Araştırma Makalesi
BibTex RIS Kaynak Göster

Investigation of the adsorption of dacarbazine (DTIC), which is used as an anticancer drug, on graphene oxide by DFT calculation method

Yıl 2023, Cilt: 7 Sayı: 2, 197 - 203, 31.12.2023
https://doi.org/10.32571/ijct.1272379

Öz

Üstün özelliklerinden dolayı, grafen oksit (GO), nano-biyo araştırmacılarının biyomedikal uygulamalarda kullanımını araştırmaları için potansiyel bir aday haline gelmiştir. Akıllı tıp ve genetik mühendisliğinde grafen bazlı malzemelerin biyomedikal kullanımlarını keşfetmek için son yıllarda önemli çabalar sarf edilmiştir. Bu çalışmada, kanser tedavisinde kullanılan ticari olarak temin edilebilen dakarbazinin (DTIC) elektronik özellikleri ve GO nanokafesindeki adsorpsiyonu, yoğunluk fonksiyonel teorisi (DFT) kullanılarak hesaplanmıştır. DTIC ayrıca imidazol karboksamid olarak da bilinir. Melanom ve Hodgkin lenfoma tedavisinde kullanılan alkilleyici bir pürin analoğu kemoterapi ilacıdır. Hodgkin genellikle vinblastin, bleomisin ve doksorubisin ile kombinasyon halinde kullanır. Damar içine enjeksiyonla verilir.

Kaynakça

  • Krishnamoorthy K.; Kim G.S.; Kim S.J. Ultrason, Sonochem. 2013, 20, 644–649.
  • Mouhat F.; Coudert F. X.; Bocquet L. M. Nature Communications, 2020, 11(1)1566.
  • Valentini L.; Bittolo Bon S.; Giorgi G. Polymers (Basel), 2020, 12(7) 1596.
  • Ramesha G.K.; Kumara A.V.; Muralidhara H.B.; Sampath S. J.Colloid Interface Sci. 2011, 361 270–277.
  • Zhu J.; Wei S.; Gu H.; Rapole S.B.; Wang Q.; Luo Z.; Haldolaarachchige N.; Young D.P.; Guo Z. Environ. Sci. Technol. 2012, 46 (2) 977–985.
  • Tiwari J.N.; Mahesh K.; Le N.H.; Timilsina K.C.K.R.; Tiwari R.N.; Kim K.S. Carbon, 2013, 56 173–182.
  • Bai J.; Zhong X.; Jiang S.; Huang Y.; Duan X. Nat Mater., 2010, 5 190–194.
  • Li Z.; Fan J.; Tong C.; et al. Nanomedicine, 2019, 14(15) 2011–2025.
  • Fedotova А. K.; Prischepa S. L.; Fedotova J.; et al., Physica E: Low-dimensional Systems and Nanostructures, 2020, 117 113790.
  • Jiang J.H.; Pi J.; Jin H.; Cai J. Y. Arti Cells Nanomed Biotechnol, 2018, 46(3) 297–307.
  • Liu Z.; Robinson J.T.; Sun X.; Dai H. J. Am. Chem. Soc., 2008, 130(33) 10876–10877.
  • Hoseini-Ghahfarokhi M.; Mirkiani S.; Mozaffari N.; Abdolahi Sadatlu M.A.; Ghasemi A.; Abbaspour S.; Akbarian M.; Farjadian F.; Karimi M. International Journal of Nanomedicine, 2020, 15 9469–9496.
  • Elks J.; Ganellin C. R. The Dictionary of Drugs, 1990, 344.
  • Gaussian 09, Revision D.01, Frisch M. J.; Trucks G. W.; Schlegel H. B.; Scuseria G. E.; Robb M. A.; et all; Gaussian, Inc., Wallingford, CT, USA, (2009).
  • Perdew J. P.; Wang Y. Phys. Rev. B. Condens. Matter; 1992, 45 13244–13249.
  • Simos T. E.; Tsitouras C.; Kovalnogov V. N.; Fedorov R. V.; Generalov D. A. Mathematics (Basel), 2021, 9 664.
  • Karzazi Y.; Belghiti M.E. A.; Dafali A.; and Hammouti B. Journal of Chemical and Pharmaceutical Research, 2014, 6(4) 689-696.
  • Glendening E. D.; Landis C. R.; Weinhold F. Program. J. Comput. Chem. 2013, 341429–1437.
  • Lee C.; Yang W.; Parr R. G. Phys. Rev. B. 1988, 37, 785.
  • Wang H.; Wang X.; Wang H.; Wang L.; Liu A. J. Mol. Model., 2007, 13 147.
  • Fleming I.; Frontier Orbitals and Organic Chemical Reactions, John Wiley and Sons, NewYork,. (1976).
Yıl 2023, Cilt: 7 Sayı: 2, 197 - 203, 31.12.2023
https://doi.org/10.32571/ijct.1272379

Öz

Kaynakça

  • Krishnamoorthy K.; Kim G.S.; Kim S.J. Ultrason, Sonochem. 2013, 20, 644–649.
  • Mouhat F.; Coudert F. X.; Bocquet L. M. Nature Communications, 2020, 11(1)1566.
  • Valentini L.; Bittolo Bon S.; Giorgi G. Polymers (Basel), 2020, 12(7) 1596.
  • Ramesha G.K.; Kumara A.V.; Muralidhara H.B.; Sampath S. J.Colloid Interface Sci. 2011, 361 270–277.
  • Zhu J.; Wei S.; Gu H.; Rapole S.B.; Wang Q.; Luo Z.; Haldolaarachchige N.; Young D.P.; Guo Z. Environ. Sci. Technol. 2012, 46 (2) 977–985.
  • Tiwari J.N.; Mahesh K.; Le N.H.; Timilsina K.C.K.R.; Tiwari R.N.; Kim K.S. Carbon, 2013, 56 173–182.
  • Bai J.; Zhong X.; Jiang S.; Huang Y.; Duan X. Nat Mater., 2010, 5 190–194.
  • Li Z.; Fan J.; Tong C.; et al. Nanomedicine, 2019, 14(15) 2011–2025.
  • Fedotova А. K.; Prischepa S. L.; Fedotova J.; et al., Physica E: Low-dimensional Systems and Nanostructures, 2020, 117 113790.
  • Jiang J.H.; Pi J.; Jin H.; Cai J. Y. Arti Cells Nanomed Biotechnol, 2018, 46(3) 297–307.
  • Liu Z.; Robinson J.T.; Sun X.; Dai H. J. Am. Chem. Soc., 2008, 130(33) 10876–10877.
  • Hoseini-Ghahfarokhi M.; Mirkiani S.; Mozaffari N.; Abdolahi Sadatlu M.A.; Ghasemi A.; Abbaspour S.; Akbarian M.; Farjadian F.; Karimi M. International Journal of Nanomedicine, 2020, 15 9469–9496.
  • Elks J.; Ganellin C. R. The Dictionary of Drugs, 1990, 344.
  • Gaussian 09, Revision D.01, Frisch M. J.; Trucks G. W.; Schlegel H. B.; Scuseria G. E.; Robb M. A.; et all; Gaussian, Inc., Wallingford, CT, USA, (2009).
  • Perdew J. P.; Wang Y. Phys. Rev. B. Condens. Matter; 1992, 45 13244–13249.
  • Simos T. E.; Tsitouras C.; Kovalnogov V. N.; Fedorov R. V.; Generalov D. A. Mathematics (Basel), 2021, 9 664.
  • Karzazi Y.; Belghiti M.E. A.; Dafali A.; and Hammouti B. Journal of Chemical and Pharmaceutical Research, 2014, 6(4) 689-696.
  • Glendening E. D.; Landis C. R.; Weinhold F. Program. J. Comput. Chem. 2013, 341429–1437.
  • Lee C.; Yang W.; Parr R. G. Phys. Rev. B. 1988, 37, 785.
  • Wang H.; Wang X.; Wang H.; Wang L.; Liu A. J. Mol. Model., 2007, 13 147.
  • Fleming I.; Frontier Orbitals and Organic Chemical Reactions, John Wiley and Sons, NewYork,. (1976).
Toplam 21 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Kimya Mühendisliği
Bölüm Makale
Yazarlar

Esvet Akbaş 0000-0001-6260-5556

Begüm Çağla Akbaş 0000-0002-1926-9873

Erken Görünüm Tarihi 10 Ocak 2024
Yayımlanma Tarihi 31 Aralık 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 7 Sayı: 2

Kaynak Göster

APA Akbaş, E., & Akbaş, B. Ç. (2023). Investigation of the adsorption of dacarbazine (DTIC), which is used as an anticancer drug, on graphene oxide by DFT calculation method. International Journal of Chemistry and Technology, 7(2), 197-203. https://doi.org/10.32571/ijct.1272379
AMA Akbaş E, Akbaş BÇ. Investigation of the adsorption of dacarbazine (DTIC), which is used as an anticancer drug, on graphene oxide by DFT calculation method. Int. J. Chem. Technol. Aralık 2023;7(2):197-203. doi:10.32571/ijct.1272379
Chicago Akbaş, Esvet, ve Begüm Çağla Akbaş. “Investigation of the Adsorption of Dacarbazine (DTIC), Which Is Used As an Anticancer Drug, on Graphene Oxide by DFT Calculation Method”. International Journal of Chemistry and Technology 7, sy. 2 (Aralık 2023): 197-203. https://doi.org/10.32571/ijct.1272379.
EndNote Akbaş E, Akbaş BÇ (01 Aralık 2023) Investigation of the adsorption of dacarbazine (DTIC), which is used as an anticancer drug, on graphene oxide by DFT calculation method. International Journal of Chemistry and Technology 7 2 197–203.
IEEE E. Akbaş ve B. Ç. Akbaş, “Investigation of the adsorption of dacarbazine (DTIC), which is used as an anticancer drug, on graphene oxide by DFT calculation method”, Int. J. Chem. Technol., c. 7, sy. 2, ss. 197–203, 2023, doi: 10.32571/ijct.1272379.
ISNAD Akbaş, Esvet - Akbaş, Begüm Çağla. “Investigation of the Adsorption of Dacarbazine (DTIC), Which Is Used As an Anticancer Drug, on Graphene Oxide by DFT Calculation Method”. International Journal of Chemistry and Technology 7/2 (Aralık 2023), 197-203. https://doi.org/10.32571/ijct.1272379.
JAMA Akbaş E, Akbaş BÇ. Investigation of the adsorption of dacarbazine (DTIC), which is used as an anticancer drug, on graphene oxide by DFT calculation method. Int. J. Chem. Technol. 2023;7:197–203.
MLA Akbaş, Esvet ve Begüm Çağla Akbaş. “Investigation of the Adsorption of Dacarbazine (DTIC), Which Is Used As an Anticancer Drug, on Graphene Oxide by DFT Calculation Method”. International Journal of Chemistry and Technology, c. 7, sy. 2, 2023, ss. 197-03, doi:10.32571/ijct.1272379.
Vancouver Akbaş E, Akbaş BÇ. Investigation of the adsorption of dacarbazine (DTIC), which is used as an anticancer drug, on graphene oxide by DFT calculation method. Int. J. Chem. Technol. 2023;7(2):197-203.