Carsınoma In-Sıtu: Case Report

Abstract

The primary surface structure of the oral cavity mucous membrane is lined with squamous epithelium.86-95% of malignant tumors of the head and neck region develop from this structure. In order to determine the risk of malignant transformation of the precancerous lesion, the degree of dysplasia observed in the epithelium as a result of histopathological evaluation should be evaluated. High-grade epithelial dysplasia and carcinoma in-situ undergo irreversible change if left untreated, and ultimately result in the development of invasive carcinoma through the accumulation of genetic abnormalities caused by persistent exposure. It is most common in male over the age of 40. Tobacco, alcohol use, poor oral hygiene and chronic irritation are the most important etiological factors. Clinically, the first sign is the presence of painless ulcers. The most affected areas are; although these include the tongue, lower lip, and floor of the mouth, these types of carcinomas can occur anywhere in the mouth. In this case report; the clinical, radiological and pathological findings of a 55-year-old female patient who was diagnosed with in-situ carcinoma that started as a painless swelling in the gingiva in the maxillary anterior and right premolar region and showed extensive involvement are presented.

Keywords

• Oral cancer
• Carcinoma In-Situ
• Oral Cavity
• Cone-Beam Computed Tomography

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