Central Giant Cell Granüloma : 3 Cases Report

Abstract

Central giant cell granuloma is a rare, benign but locally aggressive bone tumor. Le-sions may show slow growth or rapid progression. They are usually characterized by painless swelling, but cases of rapid and destructive growth and destruction of alveo-lar bone have also been reported. The etiology is unknown. The involvement of the mandible is more common than the maxilla and is more common in women. It is usu-ally seen in childhood and young adults. Differential diagnosis is made with radicular cysts, odontogenic cysts, Brown's tumor and fibrous dysplasia. Conservative treat-ment options include intralesional steroids, interferon, calcitonin. Satisfactory results can be obtained with surgical treatment. In this case report, three cases of mandibular central giant cell granuloma treated surgically are presented.

Keywords

• granulom
• tumor
• benign

Santral Dev Hücreli Granüloma : 3 Vaka Raporu

Abstract

Santral dev hücreli granüloma nadir rastlanılan, benign fakat lokal agresif karakterli bir kemik tümörüdür. Lezyonlar yavaş büyüme gösterebildiği gibi hızlı seyir de gösterebilir. Genellikle ağrısız şişlikle karakterizedirler fakat hızlı ve yıkıcı bir şekilde büyüyen ve alveolar kemiği yıkıma uğratan vakalar da belirtilmiştir. Etiyolojisi tam olarak bilinmemektedir..Mandibula tutulumu maksillaya göre daha fazladır ve kadınlarda daha sık görülür. Genellikle çocukluk çağı ve genç erişkinlerde rastlanılır. Ayırıcı tanı radiküler kistler, odontojenik kistler, Brown tümörü ve fibröz displazi ile yapılır.Konservatif tedavi seçenekleri arasında intralezyonel stero-id, interferon ,kalsitonin uygulanması gösterilmektedir. Cerrahi tedavi ile tatminkar sonuçlar elde edilebilir. Bu olgu sunumunda , cerrahi olarak tedavi edilen üç adet mandibular santral dev hücreli granüloma olgusu sunulmuştur.

Keywords

• granülom
• tümör
• benign

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