Case Report

Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series

Volume: 5 Number: 2 August 29, 2025
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Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series

Abstract

Regenerative endodontic therapy is a treatment modality that facilitates continued root formation in immature teeth with necrotic pulp and periapical radiolucency. The most frequently observed causes of necrosis in an immature root include decay, improper endodontic treatments, and trauma. Necrosis of the dental pulp may adversely affect long-term tooth survival and preservation, potentially serving as a bacterial reservoir that can infect periapical tissue and the maxillofacial space. This study presents the application of regenerative endodontic treatment (RET) and concentrated growth factor (CGF) scaffolds in four distinct patients with necrotic pulp and asymptomatic apical periodontitis. During the 12-month follow-up period post-treatment, we observed resolution of symptoms, significant periapical healing, and partial root formation.

Keywords

References

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Details

Primary Language

English

Subjects

Endodontics

Journal Section

Case Report

Early Pub Date

August 26, 2025

Publication Date

August 29, 2025

Submission Date

November 27, 2024

Acceptance Date

January 8, 2025

Published in Issue

Year 2025 Volume: 5 Number: 2

APA
Karakaya, Ş., Balkanlıoğlu, E., & Kamalak, A. (2025). Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series. HRU International Journal of Dentistry and Oral Research, 5(2), 109-113. https://doi.org/10.61139/ijdor.1592081
AMA
1.Karakaya Ş, Balkanlıoğlu E, Kamalak A. Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series. HRU Int J Dent Oral Res. 2025;5(2):109-113. doi:10.61139/ijdor.1592081
Chicago
Karakaya, Şahap, Esra Balkanlıoğlu, and Aliye Kamalak. 2025. “Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series”. HRU International Journal of Dentistry and Oral Research 5 (2): 109-13. https://doi.org/10.61139/ijdor.1592081.
EndNote
Karakaya Ş, Balkanlıoğlu E, Kamalak A (August 1, 2025) Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series. HRU International Journal of Dentistry and Oral Research 5 2 109–113.
IEEE
[1]Ş. Karakaya, E. Balkanlıoğlu, and A. Kamalak, “Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series”, HRU Int J Dent Oral Res, vol. 5, no. 2, pp. 109–113, Aug. 2025, doi: 10.61139/ijdor.1592081.
ISNAD
Karakaya, Şahap - Balkanlıoğlu, Esra - Kamalak, Aliye. “Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series”. HRU International Journal of Dentistry and Oral Research 5/2 (August 1, 2025): 109-113. https://doi.org/10.61139/ijdor.1592081.
JAMA
1.Karakaya Ş, Balkanlıoğlu E, Kamalak A. Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series. HRU Int J Dent Oral Res. 2025;5:109–113.
MLA
Karakaya, Şahap, et al. “Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series”. HRU International Journal of Dentistry and Oral Research, vol. 5, no. 2, Aug. 2025, pp. 109-13, doi:10.61139/ijdor.1592081.
Vancouver
1.Şahap Karakaya, Esra Balkanlıoğlu, Aliye Kamalak. Regenerative Endodontic Treatment Applications in Immature Teeth: A Case Series. HRU Int J Dent Oral Res. 2025 Aug. 1;5(2):109-13. doi:10.61139/ijdor.1592081