Research Article

The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis

Volume: 6 Number: 3 October 25, 2023
EN

The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis

Abstract

Multiple Sclerosis (MS) is a recurrent, chronic disease of the central nervous system (CNS) characterized by various symptoms such as vision problems, balance, gait, and cognitive impairments. In MS, the decline in cognitive function can be a difficult symptom to detect, which may lead to negative consequences in work and social situations. Consequently, this decline could impact individuals' work productivity in multiple ways, including job termination, reduced working hours, and experiencing work-related adverse events. This study aims to examine the relationship between cognitive status and work productivity and activities in individuals with MS. Sociodemographic and occupational characteristics of the patients are also considered. The Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) is used to evaluate participants' cognitive status. The Work Productivity and Activity Impairment Questionnaire (WPAI:MS) is utilized to assess work productivity and activities in MS patients. Pearson correlation and regression analysis were performed to analyze the relationship between continuous variables in the study. A total of 144 patients participated in the study. Of these patients, 81.2% have relapsing-remitting MS (RRMS). Working patients make up 42.4% of these individuals. In this study, it was observed that BICAMS subtest scores for working patients were higher than those of the non-working patient group. When analyzing the causal relationship between working patients' cognitive status scores and work productivity and activities, no statistically significant result was obtained. On the other hand, it is advised to look into larger patient groups to investigate the relationship between cognitive status and employment in individuals with MS.

Keywords

Cognitive Status , Work Efficiency , Multiple Sclerosis

References

  1. Amato, M. P., Ponziani, G., Pracucci, G., Bracco, L., Siracusa, G., & Amaducci, L. (1995). Cognitive impairment in early-onset multiple sclerosis. Pattern, predictors, and impact on everyday life in a 4-year follow-up. Archives of neurology, 52(2), 168–172. https://doi.org/10.1001/archneur.1995.00540260072019
  2. Amato, M. P., Portaccio, E., Goretti, B., Zipoli, V., Hakiki, B., Giannini, M., Pastò, L., & Razzolini, L. (2010). Cognitive impairment in early stages of multiple sclerosis. Neurological Sciences: Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 31(2), 211–214. https://doi.org/10.1007/s10072-010-0376-4
  3. Anhoque, C. F., Biccas Neto, L., Domingues, S. C. A., Teixeira, A. L., & Domingues, R. B. (2012). Cognitive impairment in patients with clinically isolated syndrome. Dementia & neuropsychologia, 6(4), 266–269. https://doi.org/10.1590/S1980-57642012DN06040011
  4. Beatty, W. W., Blanco, C. R., Wilbanks, S. L., Paul, R. H., & Hames, K. A. (1995). Demographic, clinical, and cognitive characteristics of multiple sclerosis patients who continue to work. Journal of Neurologic Rehabilitation, 9(3), 167-173.
  5. Benedict, R. H., & Zivadinov, R. (2011). Risk factors for and management of cognitive dysfunction in multiple sclerosis. Nature reviews. Neurology, 7(6), 332–342. https:// doi.org/10.1038/nrneurol.2011.61
  6. Benedict, R. H., Amato, M. P., Boringa, J., Brochet, B., Foley, F., Fredrikson, S., Hamalainen, P., Hartung, H., Krupp, L., Penner, I., Reder, A. T., & Langdon, D. (2012). Brief International Cognitive Assessment for MS (BICAMS): international standards for validation. BMC neurology, 12, 55. https://doi.org/10.1186/1471-2377-12-55
  7. Benedict, R. H., Wahlig, E., Bakshi, R., Fishman, I., Munschauer, F., Zivadinov, R., & Weinstock-Guttman, B. (2005). Predicting quality of life in multiple sclerosis: accounting for physical disability, fatigue, cognition, mood disorder, personality, and behavior change. Journal of the neurological sciences, 231(1-2), 29–34. https://doi.org/10.1016/j.jns.2004.12.009
  8. Bøe Lunde, H. M., Telstad, W., Grytten, N., Kyte, L., Aarseth, J., Myhr, K. M., & Bø, L. (2014). Employment among patients with multiple sclerosis-a population study. PloS one, 9(7), e103317. https://doi.org/10.1371/ journal.pone.0103317
  9. Cinar, B. P., Kösehasanoğulları, G., Yigit, P., & Ozakbas, S. (2017). Cognitive dysfunction in patients with multiple sclerosis treated with first-line disease-modifying therapy: a multi-center, controlled study using the BICAMS battery. Neurological sciences: official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 38(2), 337–342. https://doi.org/10.1007/s10072-016-2775-7
  10. Clemens, L., & Langdon, D. (2018). How does cognition relate to employment in multiple sclerosis? A systematic review. Multiple Sclerosis and Related Disorders, 26, 183–191. https://doi.org/10.1016/j.msard.2018.09.018
APA
Koçaslan Toran, M., & Ozcan, S. (2023). The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis. International Journal of Disabilities Sports and Health Sciences, 6(3), 345-354. https://doi.org/10.33438/ijdshs.1294268
AMA
1.Koçaslan Toran M, Ozcan S. The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis. International Journal of Disabilities Sports &Health Sciences. 2023;6(3):345-354. doi:10.33438/ijdshs.1294268
Chicago
Koçaslan Toran, Meryem, and Seyda Ozcan. 2023. “The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis”. International Journal of Disabilities Sports and Health Sciences 6 (3): 345-54. https://doi.org/10.33438/ijdshs.1294268.
EndNote
Koçaslan Toran M, Ozcan S (October 1, 2023) The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis. International Journal of Disabilities Sports and Health Sciences 6 3 345–354.
IEEE
[1]M. Koçaslan Toran and S. Ozcan, “The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis”, International Journal of Disabilities Sports &Health Sciences, vol. 6, no. 3, pp. 345–354, Oct. 2023, doi: 10.33438/ijdshs.1294268.
ISNAD
Koçaslan Toran, Meryem - Ozcan, Seyda. “The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis”. International Journal of Disabilities Sports and Health Sciences 6/3 (October 1, 2023): 345-354. https://doi.org/10.33438/ijdshs.1294268.
JAMA
1.Koçaslan Toran M, Ozcan S. The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis. International Journal of Disabilities Sports &Health Sciences. 2023;6:345–354.
MLA
Koçaslan Toran, Meryem, and Seyda Ozcan. “The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis”. International Journal of Disabilities Sports and Health Sciences, vol. 6, no. 3, Oct. 2023, pp. 345-54, doi:10.33438/ijdshs.1294268.
Vancouver
1.Meryem Koçaslan Toran, Seyda Ozcan. The Effect of Cognitive Status on Work Productivity and Activities in Multiple Sclerosis. International Journal of Disabilities Sports &Health Sciences. 2023 Oct. 1;6(3):345-54. doi:10.33438/ijdshs.1294268