Comparison of Dual Task Performance, Cadence, and Walking Speed in Healthy Geriatric Individuals with Alzheimer's Dementia
Year 2026,
Volume: 9 Issue: 1, 34 - 45, 25.01.2026
Senanur Ak
,
Meral Sertel
Abstract
Purpose: Alzheimer’s Dementia (AD) affects both cognitive and motor functions, often reducing gait speed, altering cadence, and impairing dual-task performance compared to healthy aging. This study aimed to compare dual-task performance, cadence, and gait speed between individuals with AD and healthy older adults. Method: Fifty participants aged 65 and older were recruited from private care centers in Ankara. The AD group included 25 individuals with a clinical diagnosis of Alzheimer’s Dementia who could walk independently. The control group included 25 healthy older adults with independent ambulation. Dual-task performance was assessed using the Timed Up and Go (TUG) test with cognitive and motor tasks. Gait speed was measured via the 2-Minute Walk Test (2MWT), and cadence was evaluated using the Footprint Method. Cognitive status was determined using the Standardized Mini-Mental Test (SMMT). Findings: The mean age of the AD group was 76.44±8.70 years, and the control group was 70.92±5.93 years. Individuals with AD showed significantly lower dual-task performance (p=0.000), slower gait speed (p=0.000), and reduced cadence (p=0.049) compared to healthy older adults. Step length and double step length were also notably shorter in the AD group. Conclusion: Older adults with Alzheimer’s Dementia exhibit marked impairments in motor and dual-task functions compared to their healthy peers. Rehabilitation programs should incorporate motor-cognitive strategies to improve dual-task performance and gait parameters. Individualized, environment-focused interventions are crucial for promoting autonomy and reducing functional decline in AD. In healthy aging, early assessment and preventive strategies are essential for maintaining mobility and independence.
Ethical Statement
The study was reviewed by the Non-Interventional Ethics Committee of Kırıkkale University on January 11, 2023, and approved with decision number 2023.01.12.
Supporting Institution
Non.
References
-
Abernethy, B. (1988). Dual-task methodology and motor skills research: some applications and methodological constraints. Journal of Human Movement Studies, 14(3), 101–132.
-
Agüera Sánchez, M. Á., Barbancho Ma, M. Á., & García‑Casares, N. (2020). Effect of physical exercise on Alzheimer’s disease: A systematic review. Atención Primaria, 52(5), 307–318. [Pubmed] [CrossRef]
-
Alexander, N. B., Mollo, J. M., & Giordani, B. (1995). Maintenance of balance, gait patterns, and obstacle clearance in Alzheimer’s disease. Neurology, 45(5), 908–914. [Pubmed] [CrossRef]
-
Alzheimer’s Association. (2023). Alzheimer’s disease facts and figures. Alzheimer’s & Dementia, 19(4). [Pubmed] [CrossRef]
-
Baydan, M., Caliskan, H., Balam‑Yavuz, B., Aksoy, S., & Böke, B. (2020). The interaction between mild cognitive impairment with vestibulo‑ocular reflex, dynamic visual acuity and postural balance in older adults. Experimental Gerontology, 130, 110785. [Pubmed] [CrossRef]
-
Beauchet, O., Annweiler, C., Montero-Odasso, M., Fried, L. P., Kressig, R. W., & Allali, G. (2012). Gait control: A specific motor-cognitive dual task challenge in aging. Frontiers in Aging Neuroscience, 4, 83.
-
Beydoun, M. A., Beydoun, H. A., Gamaldo, A. A., Teel, A., Zonderman, A. B., & Wang, Y. (2014). Epidemiologic studies of modifiable factors associated with cognition and dementia: Systematic review and meta‑analysis. BMC Public Health, 14, 643. [Pubmed] [CrossRef]
-
Black, A., & Wood, J. (2005). Vision and falls. Clinical and Experimental Optometry, 88(4), 212–222. [Pubmed] [CrossRef]
-
Brauer, S. G., Woollacott, M., & Shumway‑Cook, A. (2001). The interacting effects of cognitive demand and recovery of postural stability in balance-impaired elderly persons. The Journals of Gerontology: Series A: Biological Sciences and Medical Sciences, 56(8), M489/M496. [Pubmed] [CrossRef]
-
Brinton, R. D. (2008). Estrogen‑induced plasticity from cells to circuits: Predictions for cognitive function. Trends in Pharmacological Sciences, 30(4), 212–222. [Pubmed] [CrossRef]
-
Buchman, A. S., Yu, L., Boyle, P. A., Schneider, J. A., Wilson, R. S., & Bennett, D. A. (2024). The time course of motor and cognitive decline in older adults and their associations with brain pathologies. Alzheimer’s & Dementia, 20(1), 1–14. [CrossRef]
-
Burhaein, E., Demirci, N., Phytanza, D. T. P., Nadzalan, A., & Niksic, E. (2024). Is Walking A Miracle Cure For Active And Healthy Aging?. International Journal Of Active & Healthy Aging, 2(1), 10–17. [CrossRef]
-
Burns, A., Brayne, C., & Folstein, M. (1975). Key papers in geriatric psychiatry: “Mini-Mental State”: a practical method for grading the cognitive state of patients for the clinician. International Journal of Geriatric Psychiatry, 13(5), 285–294. [CrossRef]
-
Cankurtaran, M., & Arıoğul, S. (2002). New Challenges in Treatment of Alzheimer Disease and Dementia. Turkish Medical Journal, 9(3), 128-36.
-
Cevher Savcun Demirci, G., Sütçü, G., Ayvat, F., Onursal Kılınç, Ö., Doğan, M., Ayvat, E., Bekircan‑Kurt, C. E., Erdem‑Özdamar, S., Aksu Yıldırım, S., Kılınç, M., & Tan, E. (2022). Identifying a cut‑off point for Timed Up and Go test in neuromuscular diseases. Turk J Neurol, 28(1), 6–9. [CrossRef]
-
Connelly, D. M., Thomas, B. K., Cliffe, S. J., Perry, W. M., & Smith, R. E. (2009). Clinical utility of the 2-minute walk test for older adults living in long-term care. Physiotherapy Canada, 61(2), 78–87. [Pubmed] [CrossRef]
-
Demirci, C., Kılınç, M., & Aksu Yıldırım, S. (2016). The effect of dual task on clinical balance performance in ataxia patients. Turkish Journal of Physiotherapy & Rehabilitation, 27(1), 1–7.
-
Doi, T., Shimada, H., Makizako, H., Tsutsumimoto, K., Uemura, K., Anan, Y., & Suzuki, T. (2014). Dual-task gait performance in mild cognitive impairment and its role in predicting early dementia. BMC Neurology, 14, 67.
-
Douaud, G., Refsum, H., de Jager, C. A., Jacoby, R., Nichols, T. E., Smith, S. M., & Smith, A. D. (2013). Preventing Alzheimer’s disease-related gray matter atrophy by B-vitamin treatment. Proceedings of the National Academy of Sciences of the United States of America, 110(23), 9523–9528. [Pubmed] [CrossRef]
-
Dyer, A. H., Lawlor, B., & Kennelly, S. P. (2020). Gait speed, cognition and falls in people living with mild-to-moderate Alzheimer disease: data from NILVAD. BMC Geriatrics, 20(1), 117. [Pubmed] [CrossRef]
-
Eggenberger, P., Wolf, M., Schumann, M., & de Bruin, E. D. (2015). Dual-task training benefits in older adults. Frontiers in Aging Neuroscience, 8, 66.
-
Friedland, R. P. (2003). Fish consumption and the risk of Alzheimer disease. Archives of Neurology, 60(7), 923–924. [Pubmed] [CrossRef]
-
Eroymak, S., & Yiğit, V. (2020). Cost Effectiveness Analysis of Alzheimer’s Disease. Turkiye Klinikleri Journal of Health Sciences, 5(1). [CrossRef]
-
Grodstein, F., Chen, J., & Willett, W. C. (2003). High-dose antioxidant supplements and cognitive function in community-dwelling older women. American Journal of Clinical Nutrition, 77(4), 975–984. [Pubmed] [CrossRef]
-
Guralnik, J. M., Ferrucci, L., Simonsick, E. M., Salive, M. E., & Wallace, R. B. (1995). Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. The New England Journal of Medicine, 332(9), 556–561. [Pubmed] [CrossRef]
-
Güngen, C., Ertan, T., Eker, E., Yaşar, R., & Engin, F. (2002). Validity and reliability of the Standardized Mini Mental Test in the diagnosis of mild dementia in the Turkish population. Turkish Journal of Psychiatry, 13(4), 273–28. [Pubmed]
Hackett, R. A., Davies-Kershaw, H., Cadar, D., Orrell, M., & Steptoe, A. (2018). Walking speed, cognitive function, and dementia risk in the English Longitudinal Study of Ageing. Journal of the American Geriatrics Society, 66(9), 1670–1675. [Pubmed] [CrossRef]
-
Harada, C. N., Love, M. C. N., & Triebel, K. L. (2013). Normal cognitive aging. Clinics in Geriatric Medicine, 29(4), 737–752. [Pubmed] [CrossRef]
-
Işık, A., & Tanrıdağ, O. (2009). Dementia syndrome in geriatric practice. In Geriatric Syndromes Series, 4(1).
Kaye, J. A., et al. (1994). Neurologic evaluation of mental status in the older adults. Annals of Neurology, 35(6), 707–717.
-
Kim M, vd. (2024). Effects of dual‑task resistance exercise on cognition, mood, depression, functional fitness, and activities of daily living in older adults with cognitive impairment. BMC Geriatrics, 24, 369. [Pubmed] [CrossRef]
-
Knezevic, S., Toptaş Demirci, P., Stajic, D., Güven, E., & Jandrić-Kočić, M. (2024). Exercise Self-Efficacy, Body Image, and Perception of Health-Related Quality of Life in Older Adults. International Journal of Active & Healthy Aging, 2(1), 18–24. [CrossRef]
-
Kocaman, A. A., & Gencer, G. Y. (2022). Alzheimer's disease and rehabilitation. In Rehabilitation in the Elderly. Ankara: Nobel Academic Publishing.
-
Lee, K. (2017). Effects of single and dual tasks during walking on spatiotemporal gait parameters of community-dwelling older adults. Journal of Physical Therapy Science, 29(12), 1874–1877. [Pubmed] [CrossRef]
-
Li, K. Z., Bherer, L., Mirelman, A., Maidan, I., & Hausdorff, J. M. (2018). Cognitive involvement in balance, gait and dual-tasking in aging: A focused review from a neuroscience of aging perspective. Frontiers in Neurology, 9, 913. [Pubmed] [CrossRef]
-
Little, C. E., & Woollacott, M. (2014). Effect of attentional interference on balance recovery in older adults. Experimental Brain Research, 232(7), 2049–2060. [Pubmed] [CrossRef]
-
Lonie, J. A., Tierney, K. M., Herrmann, L. L., Donaghey, C., O’Carroll, R. E., Lee, A., & Ebmeier, K. P. (2009). Dual task performance in early Alzheimer’s disease, amnestic mild cognitive impairment and depression. Psychological Medicine, 39(1), 23–31. [Pubmed] [CrossRef]
-
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984). Clinical diagnosis of Alzheimer disease: Report of the NINCDS/ADRDA work group. Neurology, 34(7), 939–944. [Pubmed] [CrossRef]
-
Mercan, F. (2014). The effect of motor-motor and motor-cognitive dual tasks on balance in patients with multiple sclerosis (Master's Thesis). Dokuz Eylül University, İzmir.
-
Muñoz-Núñez, M., et al. (2018). Reliability, validity and minimal detectable change of 2-minute walk test, 6-minute walk test and 10-meter walk test in frail older adults with dementia. Archives of Gerontology and Geriatrics, 79, 36–42. [Pubmed] [CrossRef]
-
Montero-Odasso, M., Verghese, J., Beauchet, O., & Hausdorff, J. M. (2017). Gait and cognition: A complementary approach to understanding brain function and the risk of falling. Journal of the American Geriatrics Society, 65(11), 2127–2136. [Pubmed] [CrossRef]
-
Nasreddine, Z. S., Phillips, N. A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., & Chertkow, H. (2005). The Montreal Cognitive Assessment (MoCA): A brief screening tool for mild cognitive impairment. Journal of the American Geriatrics Society, 53(4), 695–699. [CrossRef]
-
Nutt, J. G., Marsden, C. D., & Thompson, P. D. (1993). Human walking and higher‑level gait disorders, particularly in the elderly. Neurology, 43(2), 268–279. [Pubmed] [CrossRef]
-
Özdilek, B., & Kenangil, G. (2014). Validation of the Turkish version of the Montreal Cognitive Assessment Scale (MoCA‑TR) in patients with Parkinson’s disease. The Clinical Neuropsychologist, 28(2), 333–343. [Pubmed] [CrossRef]
-
Özdinçler, A. R., & Yeldan, İ. (2002). Temporal distance characteristics of gait in hemiplegic patients. Physical Therapy Rehabilitation, 13(2), 96–100.
-
Özkan, H., & Üstündağ, A. (2021). The effect of dementia level on body composition and basal metabolic rate in Alzheimer’s disease. Pamukkale Medical Journal, 14(1), 201–207.
-
Peters, A. (2006). The effects of normal aging on myelin and nerve fibers: A review. Journal of Neurocytology, 34(11), 657–676. [Pubmed] [CrossRef]
-
Pettersson, A. F., Engardt, M., & Wahlund, L. O. (2002). Activity level and balance in subjects with mild Alzheimer’s disease. Dementia and Geriatric Cognitive Disorders, 13(4), 213–216. [Pubmed] [CrossRef]
-
Piva, S. R., et al. (2004). The 2-minute walk test as a predictor of functional status in older adults. Journal of Rehabilitation Research and Development, 41(4), 535–542.
-
Raz, N., & Rodrigue, K. M. (2006). Differential aging of the brain: Patterns, cognitive correlates, and modifiers. Neuroscience & Biobehavioral Reviews, 30(6), 730–748. [Pubmed] [CrossRef]
-
Rodríguez Costa, I., Abuín Porras, V., Blanco Morales, M., & Núñez Nagy, S. (2019). Dual-task and risk of falls in older adults: A cross-sectional study. International Physical Medicine & Rehabilitation Journal, 4(5):261‒263. [CrossRef]
-
Scheltens, P., Blennow, K., Breteler, M. M. B., De Strooper, B., Frisoni, G. B., Salloway, S., & Van der Flier, W. M. (2016). Alzheimer’s disease. The Lancet, 388(10043), 505–517. [Pubmed] [CrossRef]
-
O’Shea, S., Morris, M. E., & Iansek, R. (2002). Dual-task interference during gait in people with Parkinson’s disease: Effects of motor and cognitive secondary tasks. Physical Therapy, 82(9), 888–897. [Pubmed]
-
Soto, M. E., Secher, M., Gillette-Guyonnet, S., van Kan, G. A., Andrieu, S., Nourhashemi, F., & Vellas, B. (2012). Weight loss and rapid cognitive decline in community-dwelling patients with Alzheimer’s disease. Journal of Alzheimer’s Disease, 28(3), 647–654. [Pubmed] [CrossRef]
-
Srygley, J. M., Mirelman, A., Herman, T., Giladi, N., & Hausdorff, J. M. (2009). When does walking alter thinking? Age- and task-associated findings. Brain Research, 1253, 91–99. [Pubmed] [CrossRef]
-
Steffen, T. M., Hacker, T. A., & Mollinger, L. (2002). Age- and gender-related test performance in community-dwelling older adults: Six-Minute Walk Test, Berg Balance Scale, Timed Up & Go Test, and gait speeds. Physical Therapy, 82(2), 128–137. [CrossRef]
-
Turkish Statistical Institute (TÜİK). (2023). Statistics on the elderly, 2023. TÜİK.
-
United Nations. (2021). World population ageing 2021. United Nations Department of Economic and Social Affairs.
U.S. Department of Health and Human Services, National Institutes of Health, National Institute on Aging. (2015). 2014–2015 Alzheimer’s Disease Progress Report: Advancing Research Toward a Cure.
-
Verghese, J., Wang, C., Lipton, R. B., Holtzer, R., & Xue, X. (2007). Quantitative gait dysfunction and risk of cognitive decline and dementia. Journal of Neurology, Neurosurgery & Psychiatry, 78(9), 929–935. [Pubmed] [CrossRef]
-
Verhaeghen, P., Steitz, D. W., Sliwinski, M. J., & Cerella, J. (2003). Aging and dual-task performance: A meta-analysis. Psychology and Aging, 18(3), 443–460. [Pubmed] [CrossRef]
-
Viña, J., & Lloret, A. (2010). Why women have more Alzheimer’s disease than men: Gender and mitochondrial toxicity of amyloid‑beta peptide. Journal of Alzheimer’s Disease, 20(Suppl 2), S527–S533. [Pubmed] [CrossRef]
-
Vural, H., Demirin, H., Kara, Y., Eren, I., & Delibaş, N. (2010). Alterations of plasma magnesium, copper, zinc, iron and selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with Alzheimer’s disease. Journal of Trace Elements in Medicine and Biology, 24(3), 169–173. [Pubmed] [CrossRef]
-
World Health Organization (WHO). (2007). Global report on ageing and health. [CrossRef]
-
Woollacott, M., & Shumway-Cook, A. (2002). Attention and the control of posture and gait: A review of an emerging area of research. Gait & Posture, 16(1), 1–14. [Pubmed] [CrossRef]
-
Yogev-Seligmann, G., Hausdorff, J. M., & Giladi, N. (2008). The role of executive function and attention in gait. Movement Disorders, 23(3), 329–342. [Pubmed] [CrossRef]