Bacterial Social Engagements: Production and Management of Virulence in Pathogenic Bacteria of Quorum Sensing System (Interbacterial Communication) which was First Noticed in Oceans with Bioluminescence

Year 2022, Volume: 5 Issue: 2, 109 - 116, 31.12.2022

Nurdan Filik , Fethi Filik

Abstract

Quorum Sensing System (QS) is a bacteria- bacteria communication process in which bacteria use the production and detection of extracellular chemicals called autoinducers (AIs) to monitor bacteria population density. QS allows bacteria to synchronize the gene expression of the group, and thus act in unison. Once the bacteria communicate and synchronize through the AHL molecules of the QS system, they perform their vital work and operations. By proving QS, it is claimed that bacteria are not asocial, they can calculate their numbers in the environment, and some researchers may even have a so-called artificial intelligence. In this review, the QS system of Vibrio fischeri bacteria is explained and the bioluminescence feature and virulence factors in QS management is explained. While the functions of bioluminescence are not known for all animals, frequently bioluminescence is used to warn or evade predators, to lure or detect prey, and for communication between members of the same species. It has been explained that pathogenic bacteria create virulence with the T1SS, T2SS, T3SS, T4SS, T5SS, T6SS, T7SS secretion system under the control of the QS system through AHL molecules and initiate the disease process.

Keywords

Quorum Sensing System, Interbacterial Communication, Bioluminescence, Virulence, Vibrio fischeri

References

• [1] Stock, AM., Robinson, VL. and Goudreau, PN. 2000. Two-component signal transduction. Annu Rev Biochem, 69, 183-215.
• [2] Fuqua, WC., Winans, SC., Greenberg, EP. 1994. Quorum sensing in bacteria–the luxR-luxI family of cell density-responsive transcriptional regulators. J Bacteriol, 176, 269-275.
• [3] Tınaz, GB. 2003. Quorum sensing in gram-negative bacteria. Turkish Journal of Biology, 27(2), 85-93.
• [4] Hastings, JW. and Greenberg, EP. 1999. Quorum sensing: the explanation of a curious phenomenon reveals a common characteristic of bacteria. Journal of bacteriology, 181(9): 2667-2668.
• [5] Nealson, KH., Platt, T. and Hastings, JW. 1970. Cellular control of the synthesis and activity of the bacterial luminescent system. J Bacteriol, 104, 313-322.
• [6] Tomasz, A. and Hotchkiss, RD. 1964. Regulation of the transformability of pneumococcal cultures by macromolecular cell products. Proceedings of the National Academy of Sciences of the United States of America, 51(3), 480.
• [7] Filik, N. and Kubilay, A. 2020. Aeromonas hydrophila balık patojeninde biyosensör suşlar aracılığıyla çevreyi algılama sisteminin tespiti ve virülens faktörleri. Su Ürünleri Dergisi, 37(1), 29-36.
• [8] Madigan, M., Martinko, J. 2005. eds. Brock Biology of Microorganisms (11th ed.). Prentice Hall. ISBN 978-0-13-144329-7.
• [9] Bergey, DH. and Holt, JG. (ed.). 1994. Bergey's Manual of Determinative Bacteriology (9th ed.). Baltimore: Williams & Wilkins.
• [10] Holt, JG ed. 1994. Bergey's Manual of Determinative Bacteriology (9th ed.). Williams & Wilkins. ISBN 978-0-683-00603-2.
• [11] George, M. and Garrity: 2005. Bergey's Manual of Systematic Bacteriology. 2. Auflage. Springer, New York, Volume 2: The Proteobacteria, Part B: The Gammaproteobacteria ISBN 0-387-24144-2.
• [12] Urbanczyk, H., Ast, JC., Higgins, MJ., Carson, J. and Dunlap, PV. 2007. Reclassification of Vibrio fischeri, Vibrio logei, Vibrio salmonicida and Vibrio wodanis as Aliivibrio fischeri gen. nov., comb. nov., Aliivibrio logei comb. nov., Aliivibrio salmonicida comb. nov. and Aliivibrio wodanis comb. nov. International Journal of Systematic and Evolutionary Microbiology, 57(12), 2823–2829. doi:10.1099/ijs.0.65081-0. PMID 18048732
• [13] Papenfort, K. and Bassler, BL. 2016. Quorum sensing signal-response systems in Gram-negative bacteria. Nat Rev Microbiol, 14, 576-588.
• [14] Filik, F. and Kubilay, A. 2019a. Bazı Bakteriyel Balık Patojenlerinde Biyofilm Oluşumunun Farklı İn Vitro Metodlarla Tespiti. Acta Aquatica Turcica, 15(3), 378-390.
• [15] Ng, WL. and Bassler, BL. 2009. Bacterial quorum-sensing network architectures. Annual review of genetics, 43, 197-222.
• [16] Waters, CM. and Bassler, BL. 2005. Quorum sensing: cell-to-cell communication in bacteria. Annu Rev Cell De. Biol, 21, 319-346.
• [17] Lupp Claudia, 2005. Vibrio fischeri uses two quorum-sensing systems for the regulation of early and late colonization factors. J Bacteriol, 187 (11), 3620–3629. doi:10.1128/JB.187.11.3620-3629.2005. PMC 1112064. PMID 15901683 – via PMC
• [18] Lupp, C. 2003. The Vibrio fischeri quorum-sensing systems ain and lux sequentially induce luminescence gene expression and are important for persistence in the squid host. Mol Microbiol, 50 (1), 319–31. doi:10.1046/j.1365-2958.2003.t01-1-03585.x. PMID 14507383 – via PubMed
• [19] Studer, S. 2008. AinS Quorum Sensing Regulates the Vibrio fischeri Acetate Switch. J Bacteriol, 190(17), 5915–5923. doi:10.1128/JB.00148-08. PMC 2519518. PMID 18487321
• [20] Qin, N. 2007. Analysis of LuxR regulon gene expression during quorum sensing in Vibrio fischeri. J Bacteriol, 189 (11), 4127–34. doi:10.1128/JB.01779-06. PMC 1913387. PMID 1740074
• [21] Filik, N. 2020. Kültür Balıklarından İzole Edilen Aeromonas hydrophila Suşlarında Fenolik Bileşenlerin Çevreyi Algılama Sistemi Üzerine İnhibisyon Etkisi ve Suşlar Arasındaki Klonal İlişkinin Pulsed Field Jel Elektroforez Yöntemiyle Belirlenmesi. TC. Isparta Uygulamalı Bilimler Üniversitesi Lisansüstü Eğitim Enstitüsü, Doktora Tezi.
• [22] Hastings, JW. and Gibson, QH. 1963. Intermediates in the bioluminescent oxidation of reduced flavin mononucleotide. J. Biol. Chem, 238, 2537-2554.
• [23] McElroy, WD. and Green, AA., 1955. Enzymatic properties of bacterial luciferase. Arch. Biochem. Biophys, 56, 240-255.
• [24] Nunes-Halldorson, VDS. and Duran, NL. 2003. Bioluminescent bacteria: lux genes as environmental biosensors. Brazilian journal of Microbiology, 34, 91-96.
• [25] Nealson, KH. 1977. Autoinduction of bacterial luciferase. Ocurrence, Mechanism and Significance. Arch Microbiol, 112, 73-79.
• [26] Wilson, T. and Hastings, JW. 1998. Bioluminescence. Annu Rev Cell Dev Biol, 14, 197-230.
• [27] Hastings, JW. and Nealson, KH. 1981. The symbiotic luminous bacteria. In: Starr, M.P., Stolp, H., Truper, H.G., Balows, A., Schkegel, H.G. (eds.). Prokaryotes: A handbook of habitats, isolation and identification bacteria. Springer-Verlag, New York, p. 1332-1345.
• [28] von Bodman, SB., Majerczak, DR. and Coplin, DL. 1998. A negative regulator mediates quorum-sensing control of exopolysaccharide production in Pantoea stewartii subsp. stewartii. Proc Natl Acad Sci, 95, 7687-7692.
• [29] Meighen, E. and Dunlap, PV. 1993. Physiological, biochemical and genetic control of bacterial luminscence. Adv Microb Physiol, 34, 1-67.
• [30] Jones, BW. and Nishiguchi, MK. 2004. Counterillumination in the hawaiian bobtail squid, Euprymna scolopes Berry (Mollusca: Cephalopoda) (PDF). Marine Biology, 144 (6), 1151–1155. doi: 10.1007/s00227-003-1285-3. S2CID 86576334
• [31] Visick, KL. and McFall-Ngai, MJ. 2000. An exclusive contract: specificity in the Vibrio fischeri-Euprymna scolopes partnership. Journal of Bacteriology, 182(7), 1779-1787.
• [32] Aydar, AÖ. 2014. Bakteriler Konuşuyor mu? Bilim ve Teknik Mayıs, Ege Üniversitesi Tıp Fakültesi 3. sınıf öğrencisi.
• [33] Freeman Scott, Jon C. 2007. Herron. Evolutionary Analysis (4th ed. bas.). New Jersey: Pearson Prentice Hall.
• [34] Nurcan, N. 2010. Bazı Gram-Negatif Bakteriyel Balık Patojenlerinde Çevreyi Algılama Sisteminin İncelenmesi. TC. Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü, Yüksek Lisans Tezi.
• [35] Gülay, Z. 2010. İnfeksiyon Patogenezi. Solunum Sistemi İnfeksiyonları, 11-47, http://www.toraks.org.tr. http://www.toraks.org.tr/toraks-kitappdf/ solunum_sistemi_PDF/03.pdf
• [36] Novick, RP. and Geisinger, E. 2008. Quorum sensing in staphylococci. Annu Rev Genet, 42, 541–564.
• [37] Saraçlı, MA. 2006. "Quorum sensing": mikroorganizmalar iletişim mi kuruyor? Gülhane Tıp Dergisi, 48(4): 244-250.
• [38] Miller, MB. and Bassler, BL. 2001. Quorum sensing in bacteria. Annu Rev Microbiol, 55, 165–199.
• [39] Diggle, SP., Griffin, AS., Campbell, GS. and West, SA. 2007. Cooperation and conflict in quorum-sensing bacterial populations. Nature, 450, 411–414.
• [40] Antonioli, L., Blandizzi, C, Pacher, P., Guilliams, M., and Hasko G. 2018. Quorum sensing in the immune system. Nat Rev Immunol, 18, 537–538.
• [41] Li, X., Jin, J., Zhang, X., Xu, F., Zhong, J., Yin, Z. and Shuai, J. 2021. Quantifying the optimal strategy of population control of quorum sensing network in Escherichia coli. NPJ Systems Biology and Applications, 7(1), 1-16. [42] Filik, F. 2019. Bazı Bakteriyel Balık Patojenlerinde Biyofilm Oluşumuna Farklı Maddelerin İn Vitro Etkisinin Tespiti. TC. Isparta Uygulamalı Bilimler Üniversitesi Lisansüstü Eğitim Enstitüsü, Yüksek Lisans Tezi.
• [43] Filik, N. and Kubilay, A. 2019b. Yersinia ruckeri suşlarında çevreyi algılama sistemi ve yönetimindeki virülens faktörlerinin araştırılması. Acta Aquatica Turcica, 15(3), 391-403. https://doi.org/10.22392/actaquatr.537802
• [44] Speare, L., Woo, M., Bultman, KM., Mandel, MJ., Wollenberg, MS. and Septer, AN. 2021. Host-Like Conditions Are Required for T6SS-Mediated Competition among Vibrio fischeri Light Organ Symbionts. mSphere, 6(4), e01288-20.
• [45] Cohen, JJ., Eichinger, SJ., Witte, DA., Cook, CJ., Fidopiastis, PM., Tepavčević, J. and Visick, KL. 2021. Control of Competence in Vibrio fischeri. Applied and Environmental Microbiology, 87(6), e01962-20.