Battery pack is one of the most important powertraincomponents in Electric Vehicles (EV). The performance of battery pack directlyaffects vehicle’s range and performance. Configuration of cells and modulesinside battery pack also plays an important role on battery performance andsafety. In this study, the work deals with an electric vehicle that has 400 VDC bus voltage and 78 kWh total energy content. When the vehicle’s battery isdesigned, the criteria to be focused on are evaluated for three differentconfigurations of given cell quantity. Thus, optimum design solution can beachieved. According to calculations, cost analysis, total electrical power lossand most efficient solution scenarios (alternatives) are determined for thesethree different configurations afterwards system complexity is optimized. Inthe first configuration, 8 series modules are selected which have 12s6p cellconfiguration. In the second configuration, there are 16 modules with 8s2pmodule combination. Each module is equipped with 12s3p cell configuration. Lastconfiguration has 16 modules in series where each module has 6s6p cellconfiguration. Advantages and disadvantages of the systems arerevealed as a result of the calculations made for each configuration.