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SEROPREVALENCE OF TRANSFUSION TRANSMISSIBLE INFECTIONS IN BLOOD DONORS OF A NEWLY ESTABLISHED TERTIARY CARE TEACHING HOSPITAL NEAR SUNDARBAN REGION OF WEST BENGAL

Year 2023, , 93 - 99, 30.08.2023
https://doi.org/10.33457/ijhsrp.1300738

Abstract

Objective – To study the socio-demographic profile of blood donors and to determine the seroprevalence of transfusion transmissible infections (TTIs) among them.

Materials and methods – It is a retrospective cross-sectional study for 3 years from January 2020 to December 2022. Records of the blood donors were collected from the blood bank of a tertiary care teaching hospital and were analyzed through epi info7 to find out the seroprevalence of TTIs.

Results – Among the donors majority were male (76.74%) and 1.11% were found to be seropositive for TTIs. Seroprevalence was highest for hepatitis B (0.72%) followed by hepatitis C (0.18%), syphilis (0.13%) and least for human immunodeficiency virus (0.08%); however, no donor was found to be positive for malaria. Seropositivity was highest among the age group of 31-40 years of age (47.12%).

Conclusion – Increase in public awareness regarding voluntary blood donation, meticulous donor screening and regular use of highly sensitive tests are essential to reduce the risk of TTIs.

Supporting Institution

Diamond Harbour Govt Medical College and Hospital

References

  • Pallavi P., Ganesh C.K, JayashreeK., Manjunath G.V.,“Seroprevalence and Trends in Transfusion Transmitted Infections Among Blood Donors in a University Hospital Blood Bank: A 5 Year Study”,Indian J Hematol Blood Transfus, 27,1–6, 2011.
  • Stramer S.L., Hollinger F.B., Katz L.M., Kleinman S., Metzel P.S., Gregory K.R., et al.,“Emerging infectious disease agents and their potential threat to transfusion safety”,Transfus, 49, 1S–29S,2009.
  • Kitchen A.D., Barbara J.A.,Practical Transfusion Medicine, John Wiley &Sons Ltd., New York, 2001.
  • Ataro Z., Urgessa F., Wasihun T.,“Prevalence and trends of major transfusion transmissible infections among blood donors in Dire Dawa blood bank, Eastern Ethiopia: Retrospective study”,Ethiop J Health Sci, 28(6),701–10, 2018.
  • Shukla R.S., Bhuyan K.K.,“Can data on HIV sero-reactivity among blood donors provide an insight into HIV prevalence in the general population?”,Indian J Public Health, 51,14-21, 2007.
  • Shrestha A.C., Ghimire P., Tiwari B.R., Rajkarnikar M., “Transfusion-transmissible infections among blood donors in Kathmandu, Nepal”, J Infect Dev Ctries, 3, 794-7, 2009.
  • National AIDS Control Organization. Standards for Blood Banks and Blood Transfusion Services, New Delhi: Ministry of Health and Family Welfare Government of India,2007.
  • Adhikary R., Bhavana M.V.,“The risk of transfusion transmissible infections. Where do we stand in 2018?”,Glob J Transfus Med, 3(2), 88, 2018.
  • Sachan D., Varghese J., Joseph J., Srinivasan V., Jayanthi V., Rela M.,“HBsAg positive patient characteristics in hospital and blood donation camps”,ISRN Hematol, 675191, 2013.
  • Narahari S., Juwle A., Basak S., Saranath D.,“Prevalence and geographic distribution of hepatitis C virus genotype in Indian patient cohort”,Infect Genet Evol, 9(4), 643–5, 2009.
  • Meena G.C., Beelwal D., Tailor S.B., Sunaria R.K.,“Seroprevalence of transfusion transmissible infections among blood donors at a tertiary care teaching hospital in Ajmer, Rajasthan: a 5-year study”,Asian J Pharm Clin Res,15(9), 230-233, 2022.
  • Giri P.A., Deshpande J.D., Phalke D.B., Karle L.B.,“Seroprevalence of transfusion transmissible infections among voluntary blood donors at a tertiary care teaching hospital in rural area of India”,J Family Med Prim Care, 1, 48-51, 2012.
  • Tiwari B.R., Ghimmire P., Karki S., Rajkarnikar M.,“Seroprevalence of human immunodeficiency virus in Nepalese blood donors: A study from three regional blood transfusion services”,Asian J Transfus Sci, 2, 66-8, 2008.
  • Bhawani Y., Rao P.R., Sudhakar V.,“The seroprevalence of transfusion transmissible infection among the blood donors in a tertiary care hospital of Andhra Pradesh”,Biol Med, 2, 45-8, 2010.
  • Kaur H., Manjari M., Thaman R.G., Sing G.,“Prevalence of markers of hepatitis C virus among the blood donors”,J Clin Diag Res, 6, 959-62, 2012.
  • Adhikary M., Mazumdar M., Mukhopadhyay S.G., Phukan J.P., Sana P.K., Jain B.B.,“Seroprevalence of transfusion-transmitted infections among blood donors in a newly established medical college of Eastern India”,Iraqi J Hematol,10, 134-8, 2021.
  • Bhaumik P., Debnath K.,“Prevalence of blood-borne viral infections among blood donors of Tripura”,Euroasian J Hepatogastroenterol, 4, 79-82, 2014.
  • NACO. Voluntary Blood Donation Programme – An Operational Guideline, New Delhi, NACO, 2007.
  • Karmakar P.R., Shrivastava P., Ray T.G.,“Seroprevalence of transfusion transmissible infections among blood donors at the blood bank of a medical college of Kolkata”,Indian J Public Health, 58, 61-4, 2014.
  • Qureshi M.Z., Bashir H., Maroof P., Jeelani S., Bhat N., Akhter F.,“Seropositivity of hepatitis B virus and hepatitis C virus among blood donors at a tertiary care hospital in Kashmir: A ten-year study”,Int J Cur Res Rev, 8, 17-20, 2016.
  • Leena M.S., Shafee M.,“Trend and prevalence of transfusion-transmitted infections among blood donors in rural teaching institute, South India”,J Pathol Nepal, 2, 203-6, 2012.
  • Terenpuntsag B., Oupbileg L., Nelson K., McNutt L.A.,“Prevalence of infectious diseases among Mangolian blood donors”,J Infect Dev Ctries, 2, 73-5, 2008.
  • Chandekar S.A., Amonkar G.P., Desai H.M., Valvi N., Puranik G.V.,“Seroprevalence of transfusion-transmitted infections in healthy blood donors: A 5-year tertiary care hospital experience”,J Lab Physicians, 9, 283-7, 2017.
  • Chauhan S.C., Solanki P.K.,“A study of transfusion transmissible infections in blood donors in the blood bank of north Gujarat”,Indian J Pathol Oncol, 8(1), 55-58, 2021.
Year 2023, , 93 - 99, 30.08.2023
https://doi.org/10.33457/ijhsrp.1300738

Abstract

References

  • Pallavi P., Ganesh C.K, JayashreeK., Manjunath G.V.,“Seroprevalence and Trends in Transfusion Transmitted Infections Among Blood Donors in a University Hospital Blood Bank: A 5 Year Study”,Indian J Hematol Blood Transfus, 27,1–6, 2011.
  • Stramer S.L., Hollinger F.B., Katz L.M., Kleinman S., Metzel P.S., Gregory K.R., et al.,“Emerging infectious disease agents and their potential threat to transfusion safety”,Transfus, 49, 1S–29S,2009.
  • Kitchen A.D., Barbara J.A.,Practical Transfusion Medicine, John Wiley &Sons Ltd., New York, 2001.
  • Ataro Z., Urgessa F., Wasihun T.,“Prevalence and trends of major transfusion transmissible infections among blood donors in Dire Dawa blood bank, Eastern Ethiopia: Retrospective study”,Ethiop J Health Sci, 28(6),701–10, 2018.
  • Shukla R.S., Bhuyan K.K.,“Can data on HIV sero-reactivity among blood donors provide an insight into HIV prevalence in the general population?”,Indian J Public Health, 51,14-21, 2007.
  • Shrestha A.C., Ghimire P., Tiwari B.R., Rajkarnikar M., “Transfusion-transmissible infections among blood donors in Kathmandu, Nepal”, J Infect Dev Ctries, 3, 794-7, 2009.
  • National AIDS Control Organization. Standards for Blood Banks and Blood Transfusion Services, New Delhi: Ministry of Health and Family Welfare Government of India,2007.
  • Adhikary R., Bhavana M.V.,“The risk of transfusion transmissible infections. Where do we stand in 2018?”,Glob J Transfus Med, 3(2), 88, 2018.
  • Sachan D., Varghese J., Joseph J., Srinivasan V., Jayanthi V., Rela M.,“HBsAg positive patient characteristics in hospital and blood donation camps”,ISRN Hematol, 675191, 2013.
  • Narahari S., Juwle A., Basak S., Saranath D.,“Prevalence and geographic distribution of hepatitis C virus genotype in Indian patient cohort”,Infect Genet Evol, 9(4), 643–5, 2009.
  • Meena G.C., Beelwal D., Tailor S.B., Sunaria R.K.,“Seroprevalence of transfusion transmissible infections among blood donors at a tertiary care teaching hospital in Ajmer, Rajasthan: a 5-year study”,Asian J Pharm Clin Res,15(9), 230-233, 2022.
  • Giri P.A., Deshpande J.D., Phalke D.B., Karle L.B.,“Seroprevalence of transfusion transmissible infections among voluntary blood donors at a tertiary care teaching hospital in rural area of India”,J Family Med Prim Care, 1, 48-51, 2012.
  • Tiwari B.R., Ghimmire P., Karki S., Rajkarnikar M.,“Seroprevalence of human immunodeficiency virus in Nepalese blood donors: A study from three regional blood transfusion services”,Asian J Transfus Sci, 2, 66-8, 2008.
  • Bhawani Y., Rao P.R., Sudhakar V.,“The seroprevalence of transfusion transmissible infection among the blood donors in a tertiary care hospital of Andhra Pradesh”,Biol Med, 2, 45-8, 2010.
  • Kaur H., Manjari M., Thaman R.G., Sing G.,“Prevalence of markers of hepatitis C virus among the blood donors”,J Clin Diag Res, 6, 959-62, 2012.
  • Adhikary M., Mazumdar M., Mukhopadhyay S.G., Phukan J.P., Sana P.K., Jain B.B.,“Seroprevalence of transfusion-transmitted infections among blood donors in a newly established medical college of Eastern India”,Iraqi J Hematol,10, 134-8, 2021.
  • Bhaumik P., Debnath K.,“Prevalence of blood-borne viral infections among blood donors of Tripura”,Euroasian J Hepatogastroenterol, 4, 79-82, 2014.
  • NACO. Voluntary Blood Donation Programme – An Operational Guideline, New Delhi, NACO, 2007.
  • Karmakar P.R., Shrivastava P., Ray T.G.,“Seroprevalence of transfusion transmissible infections among blood donors at the blood bank of a medical college of Kolkata”,Indian J Public Health, 58, 61-4, 2014.
  • Qureshi M.Z., Bashir H., Maroof P., Jeelani S., Bhat N., Akhter F.,“Seropositivity of hepatitis B virus and hepatitis C virus among blood donors at a tertiary care hospital in Kashmir: A ten-year study”,Int J Cur Res Rev, 8, 17-20, 2016.
  • Leena M.S., Shafee M.,“Trend and prevalence of transfusion-transmitted infections among blood donors in rural teaching institute, South India”,J Pathol Nepal, 2, 203-6, 2012.
  • Terenpuntsag B., Oupbileg L., Nelson K., McNutt L.A.,“Prevalence of infectious diseases among Mangolian blood donors”,J Infect Dev Ctries, 2, 73-5, 2008.
  • Chandekar S.A., Amonkar G.P., Desai H.M., Valvi N., Puranik G.V.,“Seroprevalence of transfusion-transmitted infections in healthy blood donors: A 5-year tertiary care hospital experience”,J Lab Physicians, 9, 283-7, 2017.
  • Chauhan S.C., Solanki P.K.,“A study of transfusion transmissible infections in blood donors in the blood bank of north Gujarat”,Indian J Pathol Oncol, 8(1), 55-58, 2021.
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Details

Primary Language English
Subjects Health Care Administration
Journal Section Article
Authors

Sukla Mıtra 0000-0002-6632-2120

Soumitra Das This is me 0009-0009-3688-4817

Santanu Saha This is me 0009-0001-6096-1511

Publication Date August 30, 2023
Submission Date May 25, 2023
Acceptance Date August 9, 2023
Published in Issue Year 2023

Cite

IEEE S. Mıtra, S. Das, and S. Saha, “SEROPREVALENCE OF TRANSFUSION TRANSMISSIBLE INFECTIONS IN BLOOD DONORS OF A NEWLY ESTABLISHED TERTIARY CARE TEACHING HOSPITAL NEAR SUNDARBAN REGION OF WEST BENGAL”, IJHSRP, vol. 8, no. 2, pp. 93–99, 2023, doi: 10.33457/ijhsrp.1300738.

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