Research Article

FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW

Volume: 11 Number: 2 June 24, 2026

FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW

Abstract

Research is essential to understanding and addressing complex health challenges. Healthcare institutions play a critical role in advancing inclusive research strategies that enable effective patient recruitment. Despite this, patient engagement in research remains persistently low and often fails to reflect the diversity of the populations served. Inadequate recruitment is a long-standing challenge and a leading cause of study failure or early discontinuation, resulting in underpowered studies, inconclusive findings, and unanswered research questions. Gaining a deeper understanding of the factors influencing patients’ willingness to participate in research is therefore essential for healthcare institutions, policymakers, and researchers seeking to design more effective and equitable recruitment strategies. A narrative review of the literature was undertaken which aimed to explore the factors that influence patient recruitment and participation in research studies within healthcare settings. Eleven articles were analysed revealing four key themes influencing patient recruitment: (1) altruistic intent, (2) adaptive research strategies for patient recruitment, (3) the importance of strengthening communication strategies in research, and (4) the civic duty of healthcare organisations. These themes highlight the interplay between individual and organisational influences on patients’ decisions to engage in research. The findings indicate that a paradigm shift is required, moving beyond the repeated identification of barriers and facilitators affecting research participation towards the development, implementation, and evaluation of targeted, evidence-based strategies that promote equitable and inclusive patient participation in research.

Keywords

Ethical Statement

This narrative review involved retrospective analysis of published, peer-reviewed research. No patient records, identifiable data, or primary data collection were used. In line with Health Research Authority (HRA) guidance (2022), ethical approval and local committee approval were not required.

References

  1. E. Isaksson, P. Wester, A. C. Laska, P. Näsman, and E. Lundström, “Identifying important barriers to recruitment of patients in randomised clinical studies using a questionnaire for study personnel,” Trials, vol. 20, no. 1, 2019, doi: 10.1186/s13063-019-3737-1.
  2. L. Jonker and S. J. Fisher, “The correlation between National Health Service trusts' clinical trial activity and both mortality rates and care quality commission ratings: A retrospective cross-sectional study,” Public Health, vol. 157, pp. 1–6, 2018, doi: 10.1016/j.puhe.2017.12.022.
  3. D. H. Bodicoat, A. C. Routen, A. Willis, W. Ekezie, C. Gillies, C. Lawson, T. Yates, F. Zaccardi, M. J. Davies, and K. Khunti, “Promoting inclusion in clinical trials—A rapid review of the literature and recommendations for action,” Trials, vol. 22, no. 1, 2021, doi: 10.1186/s13063-021-05849-7.
  4. A. C. Fanaroff, S. Li, L. E. Webb, V. Miller, A. M. Navar, E. D. Peterson, and T. Y. Wang, “An observational study of the association of video- versus text-based informed consent with multicenter trial enrollment,” Circ. Cardiovasc. Qual. Outcomes, vol. 11, no. 4, Art. no. e004675, 2018, doi: 10.1161/CIRCOUTCOMES.118.004675.
  5. D. M. Shahian, D. McCloskey, X. Liu, E. Schneider, D. Cheng, and E. A. Mort, “The association of hospital research publications and clinical quality,” Health Serv. Res., vol. 57, no. 3, pp. 587–597, 2022, doi: 10.1111/1475-6773.13947.
  6. D. J. Borg, M. Haritopoulou-Sinanidou, P. Gabrovska, H.-W. Tseng, D. Honeyman, D. Schweitzer, and K. M. Rae, “Barriers and facilitators for recruiting and retaining male participants into longitudinal health research: A systematic review,” BMC Med. Res. Methodol., vol. 24, no. 1, 2024, doi: 10.1186/s12874-024-02163-z.
  7. A. A. Adegnika, J. H. Amuasi, P. Basinga, D. Berhanu, A. A. Medhanyie, Y. B. Okwaraji, L. Å. Persson, B. Savadogo, J. Schellenberg, and P. Steinmann, “Embed capacity development within all global health research,” BMJ Glob. Health, vol. 6, no. 2, Art. no. e004692, 2021, doi: 10.1136/bmjgh-2020-004692.
  8. R. Mansour, H. Naal, T. Kishawi, N. E. Achi, L. Hneiny, and S. Saleh, “Health research capacity building of health workers in fragile and conflict-affected settings: A scoping review of challenges, strengths, and recommendations,” Health Res. Policy Syst., vol. 19, no. 1, 2021, doi: 10.1186/s12961-021-00725-x.

Details

Primary Language

English

Subjects

Nursing (Other)

Journal Section

Research Article

Publication Date

June 24, 2026

Submission Date

January 29, 2026

Acceptance Date

June 20, 2026

Published in Issue

Year 2026 Volume: 11 Number: 2

APA
Whitby, E., & Rylance-Graham, R. (2026). FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW. International Journal of Health Services Research and Policy, 11(2), 160-181. https://doi.org/10.33457/ijhsrp.1867190
AMA
1.Whitby E, Rylance-Graham R. FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW. IJHSRP. 2026;11(2):160-181. doi:10.33457/ijhsrp.1867190
Chicago
Whitby, Emma, and Rebecca Rylance-Graham. 2026. “FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW”. International Journal of Health Services Research and Policy 11 (2): 160-81. https://doi.org/10.33457/ijhsrp.1867190.
EndNote
Whitby E, Rylance-Graham R (June 1, 2026) FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW. International Journal of Health Services Research and Policy 11 2 160–181.
IEEE
[1]E. Whitby and R. Rylance-Graham, “FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW”, IJHSRP, vol. 11, no. 2, pp. 160–181, June 2026, doi: 10.33457/ijhsrp.1867190.
ISNAD
Whitby, Emma - Rylance-Graham, Rebecca. “FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW”. International Journal of Health Services Research and Policy 11/2 (June 1, 2026): 160-181. https://doi.org/10.33457/ijhsrp.1867190.
JAMA
1.Whitby E, Rylance-Graham R. FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW. IJHSRP. 2026;11:160–181.
MLA
Whitby, Emma, and Rebecca Rylance-Graham. “FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW”. International Journal of Health Services Research and Policy, vol. 11, no. 2, June 2026, pp. 160-81, doi:10.33457/ijhsrp.1867190.
Vancouver
1.Emma Whitby, Rebecca Rylance-Graham. FACTORS INFLUENCING PATIENT RECRUITMENT INTO HEALTHCARE RESEARCH: A QUALITATIVE NARRATIVE REVIEW. IJHSRP. 2026 Jun. 1;11(2):160-81. doi:10.33457/ijhsrp.1867190

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