Research Article

EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA

Volume: 5 Number: 3 December 25, 2020
EN

EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA

Abstract

Abstract:Prostate Cancer (PCA) is the most common among urological malignant tumors. Prostate cancer patients may be unable to urinate, and may have hospital admissions with symptoms like erectile dysfunction or hematuria. Although hematuria is a highly common clinical manifestation in the society, the frequency of it is not known in prostate cancer patients, which is one of the urological malignancies. The purpose of this study was to investigate the relation of RDW (distribution width of the red blood cells), MPV (mean platelet volüme) and Platelet Blood Parameters with hematuria in prostate cancer patients admitting to the emergency clinic with hematuria. The present study was conducted retrospectively by examining the hospital automation system and patient files of prostate cancer patients admitting with hematuria between 01.01.2018-01.01.2020 to Yozgat Bozok University Emergency Medical Clinic. A total of 60 patients with full files and that matched study criteria were included in the study. For the purpose of comparing blood parameters for the purpose of comparing blood parameters, 45 patients with prostate cancer, nonspecific complaints and non-additional diseases were evaluated as the control group. MPV (mean platelet volume), RDW-CV (red blood cells distribution width) blood parameters of patients with prostate cancer hematuria were found to be significantly higher in the control group. Platelet value of the patient group was found to be significantly lower than the control group. However, the platelet blood parameter values were significantly lower in patients with major hematuria than in patients with minor hematuria (<0.05). According to the results of the present study, we believe that all the three parameters (RDW, MPV and Platelet levels), which can be measured in full blood count in the prostate cancer patient group in particular, can guide clinicians that the finding of hematuria can develop, and will be beneficial in follow-up and treatment. However, unlike RDW and MPV laboratory parameters, we think the Platelet parameter is an important parameter in predicting the type of hematuria that can develop.

Keywords

Supporting Institution

none

Project Number

2019-11-280

References

  1. [1]Thomas Gillispie Smith MC III. Urologic surgery In: Townsend C, Beauchamp RD, Evers BM, et al. (eds) “Sabiston textbook of surgery: the biological basis of modern surgical practice.” 20th ed. New York: Elsevier, 2100–2102, 2017.
  2. [2] Narayan VM, Konety BR and Warlick C. “Novel biomarkers for prostate cancer: an evidence-based review for use in clinical practice” Int J Urol ,24(5), 352–360, 2017.
  3. [3] Siegel RL,Miller KD, Jemal A.” Cancer Istatistics” A Cancer J Clin, 65:5-29,2015.
  4. [4] Nice. “Suspected cancer: recognition and referral” 1–95,2015.
  5. [5] Hsieh YP, Chang CC, Kor CT, Yang Y, Wen YK, Chiu PF “The Predictive Role of Red Cell Distribution Width in Mortality among Chronic Kidney Disease Patients” PLoS One.,11(12):e0162025, 2016.
  6. [6] Khadra MH, Pickard RS, Charlton M, et al. “A prospective analysis of 1,930 patients with hematuria to evaluate current diagnostic practice” J Urol, 163(2): 524–527,2000.
  7. [7.] Mariani AJ, Mariani MC, Macchioni C “The significance of adult hematuria: 1,000 hematuria evaluations including a riskbenefit and cost-effectiveness analysis” J Urol. 141: 350–355,1989.
  8. [8] Sun Y, Zhang Y, Zhu Y, Zhang A, Huang S, Yin X, Ding G, Liu M, Jia Z.”Inhibition of mitochondrial complex-1 restores the downregulation of aquaporins in obstructive nephropathy” Am J Physiol Renal Physiol. 1; 311(4),777-786,2016.

Details

Primary Language

English

Subjects

Clinical Sciences

Journal Section

Research Article

Publication Date

December 25, 2020

Submission Date

September 16, 2020

Acceptance Date

November 24, 2020

Published in Issue

Year 2020 Volume: 5 Number: 3

APA
Atik, D. (2020). EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA. International Journal of Health Services Research and Policy, 5(3), 265-275. https://doi.org/10.33457/ijhsrp.795668
AMA
1.Atik D. EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA. IJHSRP. 2020;5(3):265-275. doi:10.33457/ijhsrp.795668
Chicago
Atik, Dilek. 2020. “EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA”. International Journal of Health Services Research and Policy 5 (3): 265-75. https://doi.org/10.33457/ijhsrp.795668.
EndNote
Atik D (December 1, 2020) EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA. International Journal of Health Services Research and Policy 5 3 265–275.
IEEE
[1]D. Atik, “EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA”, IJHSRP, vol. 5, no. 3, pp. 265–275, Dec. 2020, doi: 10.33457/ijhsrp.795668.
ISNAD
Atik, Dilek. “EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA”. International Journal of Health Services Research and Policy 5/3 (December 1, 2020): 265-275. https://doi.org/10.33457/ijhsrp.795668.
JAMA
1.Atik D. EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA. IJHSRP. 2020;5:265–275.
MLA
Atik, Dilek. “EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA”. International Journal of Health Services Research and Policy, vol. 5, no. 3, Dec. 2020, pp. 265-7, doi:10.33457/ijhsrp.795668.
Vancouver
1.Dilek Atik. EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA. IJHSRP. 2020 Dec. 1;5(3):265-7. doi:10.33457/ijhsrp.795668

320px-DOAJ_logo-black-whitespace.svg.pngscholar_logo_64dp.png  crossref-logo-landscape-200.png  logo-minik.png  CenterLogo.png  SciLit logo ile ilgili görsel sonucu  icon.png?w=170&fakeurl=1Medical Reads 

  Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial -NoDerivatives 4.0 International License.