DOES THE FREQUENCY OF ACUTE CHOLECYSTITIS DECREASE DURING THE RAMADAN MONTH?

Year 2021, Volume: 6 Issue: 3, 337 - 344, 29.12.2021

Murat Seyit , Atakan Yılmaz , Sevda Yılmaz , Mert Özen

https://doi.org/10.33457/ijhsrp.950566

Abstract

The pathophysiological mechanism of acute cholecystitis (AC), which is essentially the inflammation of the gallbladder, is blockage of the cystic duct, and its most common cause is gallstones. On the other hand, fasting held in Ramadan is a worship practised by Muslims within the period from dawn to sunset by avoiding any eating and drinking act. Within this framework, our study ultimately intends to reveal the variation of AC in two different time periods. We retrospectively compared the demographic characteristics, admittance times, biochemical parameters of the subjects diagnosed with AC and hospitalized in the general surgery between 2012 and 2018. We also evaluated diagnosis classification, length of hospitalization, presence of intensive care stay, presence of operation during hospitalization, and the underlying comorbid diseases of the subjects. 225 patients were hospitalized in the general surgery service after being diagnosed with AC in the ED over the course of six years, yet the total number of subjects recruited for the study is 46. Whereas 10 patients (21.7%) were admitted and hospitalized during the Ramadan month, 36 (78.3%) patients in the other group were hospitalized one month before and after the Ramadan. 16 (34.8%) of the hospitalized patients underwent emergency surgery, while 30 (65.2%) patients were operated electively. The comparison of the two cohorts in our study revealed no significant difference in relation to the demographic characteristics, laboratory findings, imaging methods, underlying comorbid diseases, and the length of hospital stay. Nevertheless, clinical investigations seem to have revealed a difference between groups.

Keywords

acute cholecystitis, general surgery, abdominal pain

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References

• [1] Yokoe, M., et al. “Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos)”, J Hepatobiliary Pancreat Sci, 25(1), 41‐54, 2018.
• [2] Abbas, SM., Basalamah, AH. “Effects of Ramadhan fast on male fertility”, Arch Androl, 16(2), 161-166, 1986.
• [3] Hosseini, SV. et al. “The effect of season and Ramadan fasting on the onset of acute cholecystitis”, Saudi Med J, 27(4), 503‐506, 2006.
• [4] Halpin, V. “Acute cholecystitis”, BMJ Clin Evid, 08, 411, 2014.
• [5] Kuroi, Y., et al. “Acute cholecystitis in patients with stroke”, Neurol India, 67(2), 439‐441, 2019.
• [6] Indar, AA., Beckingham, IJ. “Acute cholecystitis”, BMJ, 325(7365), 639‐643, 2002.
• [7] Yu, H., Uyeda, JW. “Imaging of Acute Hepatobiliary Dysfunction”, Radiol Clin North Am, 58(1), 45‐58, 2020.
• [8] Abboud, PA., et al. “Predictors of common bile duct stones prior to cholecystectomy: a meta-analysis”, Gastrointest Endosc, 44(4), 450‐455, 1996.
• [9] Wertz, JR., et al. “Comparing the Diagnostic Accuracy of Ultrasound and CT in Evaluating Acute Cholecystitis”, AJR Am J Roentgenol, 211(2), 92‐97, 2018.
• [10] Cao, Z., et al. “Risk factors of systematic biliary complications in patients with gallbladder stones”, Ir J Med Sci, 189(3), 943-947, 2020.
• [11] Goh, SNS., et al. “Improved outcomes for index cholecystectomy for acute cholecystitis following a dedicated emergency surgery and trauma service (ESAT)”, Eur J Trauma Emerg Surg, 2020. published online ahead of print, doi:10.1007/s00068-020-01308-1