Nigella sativa yağının gökkuşağı alabalığı (Oncorhynchus mykiss)’nın bağışıklık mekanizmaları üzerindeki etkileri

Abstract

Bu çalışmanın amacı, Nigella sativa yağının gökkuşağı alabalığında serum yanıtı üzerindeki etkinliğini değerlendirmektir. Balıklara %1 ve %10 dozlarında NSO intraperitoneal (i.p.) olarak enjekte edilmiştir. Serum bakterisidal aktivite, lizozim aktivitesi, miyeloperoksidaz, total protein ve total immünoglobulin seviyeleri enjeksiyondan 3, 7, 14 ve 21 gün sonra analiz edilmiştir. Aynı prosedür bir kontrol grubunda da gerçekleştirilmiştir. Tedavi grupları arasında total protein ve immünoglobulin seviyeleri hariç tüm immünolojik parametrelerde anlamlı değişiklikler olmuştur. Sonuç olarak, bu çalışma gökkuşağı alabalığının immün parametrelerinin arttığını göstermiştir. Bu nedenle, Çörek otu yağı enjeksiyonu gökkuşağı alabalığının immün yanıtı üzerinde olumlu bir etkiye yol açmaktadır.

Keywords

• Gökkuşağı alabalığı
• Oncorhynchus mykiss
• Nigella sativa yağı
• bağışıklık yanıtı

Effects of Nigella sativa oil on immune mechanisms in rainbow trout, Oncorhynchus mykiss

Abstract

The purpose of this study was to evaluate the efficacy of Nigella sativa oil on serum responses in rainbow trout. Fish were injected intraperitoneally (i.p.) with 1% and 10% doses of NSO. Serum bactericidal activity, lysozyme activity, myeloperoxidase, total protein and total immunoglobulin levels were analyzed 3, 7, 14 and 21 days after injection. The same procedure was performed in a control group. There were signif-icant changes in all immunological parameters among the treatment groups except for total protein and immunoglobulin levels. In conclusion, the present study showed that the immune parameters of rainbow trout were increased. Therefore, injection of Ni-gella sativa oil leads to a positive effect on the immune response of rainbow trout.

Keywords

• Rainbow trout
• Oncorhynchus mykiss
• Nigella sativa oil
• immune response

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