Investigating Sensor Properties of Plasmonic Gold Nanoparticles Produced By Pulsed Laser Deposition

Abstract

Plasmonic gold nanoparticles exhibit exceptional optical properties, particularly Lo-calised Surface Plasmon Resonance, which makes them ideal candidates for sensor applications. These nanoparticles are highly sensitive to changes in their surrounding environment, allowing for precise detection of molecular interactions and environ-mental shifts. In this study, we investigate the sensor properties of gold nanoparticles produced via Pulsed Laser Deposition, a clean and versatile method that allows for precise control over particle size, morphology, and distribution without the need for chemical reagents. Pulsed Laser Deposition process was optimized by adjusting laser fluence, pulse duration, and deposition time to produce gold nanoparticles with tuna-ble plasmonic properties. The structural and optical characteristics of gold nanoparti-cles were analyzed using scanning electron microscopy, and UV-Vis spectroscopy, confirming that the size and morphology of the particles were controllable through the deposition parameters. The sensor performance of gold nanoparticles was evalu-ated through localised surface plasmon resonance measurements, which demonstrated their sensitivity to small changes in the refractive index of the surrounding medium. Specifically, the shift in localised surface plasmon resonance peak was measured up-on exposure to different analytes, including protein A where a wavelength shift of 50 nm measured, indicating the high sensitivity of these nanoparticles for biosensing ap-plications. The results suggest that Pulsed Laser Deposition-produced gold nanoparti-cles possess promising sensor properties for real-time detection and environmental monitoring, offering an efficient and reproducible platform for a wide range of sens-ing applications.

Keywords

• Au nanoparticles
• LSPR
• plasmonics
• PLD

Puls Lazer Depozisyonu Yöntemiyle Üretilen Plazmonik Altın Nanoparçacıkların Sensör Özelliklerinin Araştırılması

Abstract

Plazmonik altın nanoparçacıklar (Au NP'ler), özellikle Lokalize Yüzey Plazmon Re-zonansı (LSPR) sayesinde, sensör uygulamaları için ideal adaylar olarak öne çıkan üstün optik özelliklere sahiptir. Bu nanoparçacıklar, çevrelerindeki ortamdaki deği-şimlere karşı yüksek hassasiyet gösterir ve bu sayede moleküler etkileşimlerin ve çevresel değişimlerin hassas bir şekilde tespit edilmesini sağlar. Bu çalışmada, kim-yasal reaktiflere ihtiyaç duyulmadan parçacık boyutu, morfolojisi ve dağılımı üzerin-de hassas kontrol imkânı tanıyan temiz ve çok yönlü bir yöntem olan Puls Lazer De-pozisyonu (PLD) ile üretilen altın nanoparçacıkların sensör özellikleri incelenmiştir. PLD işlemi, ayarlanabilir plazmonik özelliklere sahip altın nanoparçacıklar üretmek için lazer akısı, puls süresi ve biriktirme süresi ayarlanarak optimize edilmiştir. Altın nanoparçacıkların yapısal ve optik özellikleri, taramalı elektron mikroskobu (SEM) ve UV-Vis spektroskopisi kullanılarak analiz edilmiş ve parçacık boyutu ile morfolo-jisinin biriktirme parametreleri ile kontrol edilebildiği doğrulanmıştır. Altın nano-parçacıkların sensör performansı, çevrelerindeki ortamın kırılma indisi değişimlerine duyarlılıklarını gösteren LSPR ölçümleri ile değerlendirilmiştir. Özellikle, LSPR piki, protein A dâhil çeşitli analizlere maruz bırakıldığında 50 nm dalga boyu kayması ile ölçülmüş ve bu nanoparçacıkların biyosensör uygulamaları için yüksek hassasiyete sahip olduğunu göstermiştir. Sonuçlar, PLD ile üretilen altın nanoparçacıkların gerçek zamanlı algılama ve çevresel izleme için umut vadeden sensör özelliklerine sahip ol-duğunu ve geniş bir sensör uygulama yelpazesi için verimli ve yeniden üretilebilir bir platform sunduğunu göstermektedir.

Keywords

• Au nanoparçacıklar
• LSPR
• plazmonik
• PLD

References

1. Bai, X. et al. (2020). The basic properties of gold nanoparticles and their applications in tumor diagnosis and treatment. International journal of molecular sciences, 21(7), 2480.
2. Zhou, W. et al. (2015). Gold nanoparticles for in vitro diagnostics. Chemical reviews, 115(19), 10575-10636.
3. Ramachandran, T. et al. (2024). Gold on the horizon: unveiling the chemistry, applications and future prospects of 2D monolayers of gold nanoparticles (Au-NPs). Nanoscale Advance.
4. Ghosh, S.K. and Pal, T. (2007). Interparticle coupling effect on the surface plasmon resonance of gold nanoparticles: from theory to applications. Chemical reviews, 107(11), 4797-4862.
5. Amendola, V. et al. (2017). Surface plasmon resonance in gold nanoparticles: a review. Journal of physics: Condensed matter, 29(20), 203002.
6. Gezgin, S.Y., A. Kepceoğlu, and Kılıç, H.Ş. (2017). An investigation of localised surface plasmon resonance (LSPR) of Ag nanoparticles produced by pulsed laser deposition (PLD) technique. in AIP Conference Proceedings. AIP Publishing LLC.
7. Falahati, M. et al. (2020). Gold nanomaterials as key suppliers in biological and chemical sensing, catalysis, and medicine. Biochimica et Biophysica Acta (BBA)-General Subjects, 1864(1), 129435.
8. Hang, Y., A. Wang, and N. Wu, (2024). Plasmonic silver and gold nanoparticles: shape-and structure-modulated plasmonic functionality for point-of-caring sensing, bio-imaging and medical therapy. Chemical Society Reviews.

9. Candan, I. et al. (2024). Sensor properties of plasmonic silver and gold nanoparticles produced by pulsed laser deposition. Journal of Optoelectronics and Advanced Materials, 26(5-6), 186-198.
10. Gezgin, S.Y., A. Kepceoğlu, and H.Ş. Kılıç. (2017). An experimental investigation of localised surface plasmon resonance (LSPR) for Cu nanoparticles depending as a function of laser pulse number in Pulsed Laser Deposition. in AIP Conference Proceedings. AIP Publishing LLC.
11. Priyadarshini, E. and N. Pradhan. (2017). Gold nanoparticles as efficient sensors in colorimetric detection of toxic metal ions: a review. Sensors and Actuators B: Chemical, 238, 888-902.
12. Candan, İ. (2022). Plazmonik soy metal (Au, Ag) nanoparçacıklara dayalı sensör üretimi ve analizi. Dicle Üniversitesi Fen Bilimleri Enstitüsü.
13. Sadiq, Z. et al. (2024). Gold nanoparticles-based colorimetric assays for environmental monitoring and food safety evaluation. Critical Reviews in Analytical Chemistry, 54(7), 2209-2244.
14. Qiao, J. and L. Qi. (2021). Recent progress in plant-gold nanoparticles fabrication methods and bio-applications. Talanta, 223, 121396.
15. Escorcia-Díaz, D. et al. (2023). Advancements in nanoparticle deposition techniques for diverse substrates: a review. Nanomaterials, 13(18), 2586.
16. Gezgin, S.Y. et al. (2020). Effect of Ar gas pressure on lspr property of Au nanoparticles: comparison of experimental and theoretical studies. Nanomaterials, 10(6), 1071.
17. Gezgi̇n, S.Y.ğ.t. and H.Ş. Kılıç. (2020). An improvement on the conversion efficiency of Si/CZTS solar cells by LSPR effect of embedded plasmonic Au nanoparticles. Optical Materials, 101, 109760.
18. Jamkhande, P.G. et al. (2019). Metal nanoparticles synthesis: An overview on methods of preparation, advantages and disadvantages, and applications. Journal of drug delivery science and technology, 53, 101174.
19. Kepceoğlu, A. et al. (2019). Nonlinear optical properties of zinc oxide thin films produced by pulsed laser deposition. Materials Today: Proceedings, 18, 1819-1825.
20. Haider, A.J. et al. (2022). A comprehensive review on pulsed laser deposition technique to effective nanostructure production: Trends and challenges. Optical and Quantum Electronics, 54(8), 488.
21. Goncalves, M.R., Plasmonic nanoparticles: fabrication, simulation and experiments. Journal of Physics D: Applied Physics, 2014. 47(21): p. 213001.
22. Candan, İ. et al. (2021). Biosensor Properties Of Plasmonic Silver Nanoparticles Produced By Pld. Middle East Journal of Science, 7(2), 112-122.
23. Gezgin, S.Y. A. Kepceoğlu, and H.Ş. Kılıç. (2017). An investigation of localised surface plasmon resonance (LSPR) of Ag nanoparticles produced by pulsed laser deposition (PLD) technique. in AIP Conference Proceedings. AIP Publishing.
24. Gezgin, S.Y. et al. (2016). Plasmonic tuning of gold doped thin films for layers of photovoltaic devices. in AIP Conference Proceedings. AIP Publishing.
25. Gezgin, S.Y. A. Kepceoğlu, and H.Ş. Kılıç. (2017). An experimental investigation of localised surface plasmon resonance (LSPR) for Cu nanoparticles depending as a function of laser pulse number in Pulsed Laser Deposition. in AIP Conference Proceedings. AIP Publishing.
26. Haiss, W. et al. (2007). Determination of size and concentration of gold nanoparticles from UV− Vis spectra. Analytical chemistry, 79(11), 4215-4221.