Hücre Zarı Sinyalinin NMR Spektroskopisi ile Belirlenmesi

Yıl 2018, , 47 - 50, 25.07.2018

Sibel Korunur Ali Yılmaz

https://doi.org/10.29132/ijpas.359756

Öz

Hücre zarı, hücrenin
sınırlarını oluşturur ve hücre içi ile dışı arasındaki madde geçişini düzenler.
Hücrenin kendisi için gerekli besin maddelerini
dış ortamdan alıp metabolizma sonucu oluşan zararlı metabolitleri dış ortama
verme olayında hücre zarlarının büyük bir rolü bulunmaktadır. Bu çalışmada sulu çözeltideki bir hücre zarı örneğinin 400 MHz ¹H-NMR spektrumu, tek puls ve
presaturasyon metodu kullanılarak alınmış ve bu iki spektrumun
karşılaştırmasıyla hücre zarı sinyalinin yeri saptanmaya çalışılmıştır.

Anahtar Kelimeler

Hücre zarı, nükleer manyetik rezonans, presaturasyon metodu

Determination of Cell Membrane Signal by using NMR Spectroscopy

Öz

The cell membrane forms the boundaries of the cell and regulates the
passage of matter between the inside and the outside of the cell. Cell
membranes play a major role in the process of taking the necessary nutrients
from the outside and exerting the harmful metabolites resulting from the
metabolism. In this study, 400 MHz ¹H-NMR spectrum of a membrane
sample in an aqueous solution was taken using single pulse and presaturation
method and it has been tried to determine the location of the membrane signal
by comparing these two spectrums.

Anahtar Kelimeler

Cell membrane, presaturation method, nuclear magnetic resonance

Kaynakça

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