Antioxidant enhancement of Cystoseira barbata extracts via nanoliposomal encapsulation

Melih Cafer; İnci Tüney; Münevver Müge Çağal

doi:10.21448/ijsm.1622199

Antioxidant enhancement of Cystoseira barbata extracts via nanoliposomal encapsulation

Abstract

Seaweeds are well-known for their numerous health benefits, which include antioxidant, antimicrobial, antitumor, and anti-inflammatory properties. They produce secondary metabolites to withstand extreme conditions such as high temperatures, fluctuating salinity, intense sunlight, and varying oxygen levels. These compounds not only serve as protective mechanisms for the seaweeds but also hold potential for medicinal applications and other biologically active uses. In this study, we investigated the effects of nanoliposomal encapsulation on the antioxidant capacity of extracts from Cystoseira barbata, collected from the Bursa/Mudanya coast. The extract was obtained from dried algal samples using ethanol solvent at a ratio of 1:1. The total phenolic content of the extract was analyzed, revealing the highest phenol concentration of 2.66 mg GAE/g. The DPPH assay was conducted to assess the antioxidant capacity of both free extract (FE) and the nanoliposomal encapsulated extract (NE). Inhibition (%) values showed a positive correlation with concentration, yielding values of 19.41 for FE and 31.33 for NE. Nanoliposomal encapsulation enhanced DPPH scavenging capacity by 61% compared to FE. Thus, the nanoliposomal encapsulation technique appears to be a promising method for enhancing the effectiveness of C. barbata extracts as antioxidant agents.

Keywords

Project Number

1139B412202623

Thanks

We thank to TUBİTAK 2209-B programme for the financial support.

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Details

Primary Language

English

Subjects

Pharmaceutical Biotechnology

Journal Section

Research Article

Authors

Melih Cafer This is me
Türkiye

İnci Tüney
0000-0003-0293-6964
Türkiye

Münevver Müge Çağal ^*
0000-0002-1786-1216
Türkiye

Early Pub Date

August 30, 2025

Publication Date

September 4, 2025

Submission Date

January 20, 2025

Acceptance Date

June 12, 2025

Published in Issue

Year 2025 Volume: 12 Number: 3

DOI

https://doi.org/10.21448/ijsm.1622199

IZ

https://izlik.org/JA33UK39XS

Cite

RIS / Bibtex

APA

Cafer, M., Tüney, İ., & Çağal, M. M. (2025). Antioxidant enhancement of Cystoseira barbata extracts via nanoliposomal encapsulation. International Journal of Secondary Metabolite, 12(3), 732-742. https://doi.org/10.21448/ijsm.1622199

AMA

1.Cafer M, Tüney İ, Çağal MM. Antioxidant enhancement of Cystoseira barbata extracts via nanoliposomal encapsulation. Int. J. Sec. Metabolite. 2025;12(3):732-742. doi:10.21448/ijsm.1622199

Chicago

Cafer, Melih, İnci Tüney, and Münevver Müge Çağal. 2025. “Antioxidant Enhancement of Cystoseira Barbata Extracts via Nanoliposomal Encapsulation”. International Journal of Secondary Metabolite 12 (3): 732-42. https://doi.org/10.21448/ijsm.1622199.

EndNote

Cafer M, Tüney İ, Çağal MM (September 1, 2025) Antioxidant enhancement of Cystoseira barbata extracts via nanoliposomal encapsulation. International Journal of Secondary Metabolite 12 3 732–742.

IEEE

[1]M. Cafer, İ. Tüney, and M. M. Çağal, “Antioxidant enhancement of Cystoseira barbata extracts via nanoliposomal encapsulation”, Int. J. Sec. Metabolite, vol. 12, no. 3, pp. 732–742, Sept. 2025, doi: 10.21448/ijsm.1622199.

ISNAD

Cafer, Melih - Tüney, İnci - Çağal, Münevver Müge. “Antioxidant Enhancement of Cystoseira Barbata Extracts via Nanoliposomal Encapsulation”. International Journal of Secondary Metabolite 12/3 (September 1, 2025): 732-742. https://doi.org/10.21448/ijsm.1622199.

JAMA

1.Cafer M, Tüney İ, Çağal MM. Antioxidant enhancement of Cystoseira barbata extracts via nanoliposomal encapsulation. Int. J. Sec. Metabolite. 2025;12:732–742.

MLA

Cafer, Melih, et al. “Antioxidant Enhancement of Cystoseira Barbata Extracts via Nanoliposomal Encapsulation”. International Journal of Secondary Metabolite, vol. 12, no. 3, Sept. 2025, pp. 732-4, doi:10.21448/ijsm.1622199.

Vancouver

1.Melih Cafer, İnci Tüney, Münevver Müge Çağal. Antioxidant enhancement of Cystoseira barbata extracts via nanoliposomal encapsulation. Int. J. Sec. Metabolite. 2025 Sep. 1;12(3):732-4. doi:10.21448/ijsm.1622199