Essential oils: A review of ex vivo studies on aortic smooth muscle contractility

Sadettin Demirel; İpek Nazlı Sinağ

Essential oils: A review of ex vivo studies on aortic smooth muscle contractility

Abstract

Essential oils, known as volatile oils, are valuable odoriferous substances from plants. The popularity of essential oils has significantly increased due to numerous therapeutic properties, including antihypertensive, antidiabetic, antidyslipidemic, and antiplatelet activities. A total of 42 essential oils were detected involved in the aorta contraction-relaxation mechanisms ex vivo. The majority of these essential oils exhibit smooth muscle relaxant effects via multiple signaling pathways. Therefore, the plant-derived essential oils may be considered a potential agent for the treatment of cardiovascular diseases. This paper provides a comprehensive review of the essential oils with vasoactive effects on the aorta function and the underlying signaling pathways involved.

Keywords

References

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Details

Primary Language

English

Subjects

Natural Products and Bioactive Compounds

Journal Section

Review

Authors

Sadettin Demirel ^*
0000-0002-3629-5344
Türkiye

İpek Nazlı Sinağ
0009-0008-8810-9276
Türkiye

Early Pub Date

July 25, 2026

Publication Date

-

Submission Date

August 28, 2025

Acceptance Date

March 9, 2026

Published in Issue

Year 2026 Number: Advanced Online Publication

IZ

https://izlik.org/JA83PJ52DA

Cite

RIS / Bibtex

APA

Demirel, S., & Sinağ, İ. N. (2026). Essential oils: A review of ex vivo studies on aortic smooth muscle contractility. International Journal of Secondary Metabolite, Advanced Online Publication. https://izlik.org/JA83PJ52DA

AMA

1.Demirel S, Sinağ İN. Essential oils: A review of ex vivo studies on aortic smooth muscle contractility. Int. J. Sec. Metabolite. 2026;(Advanced Online Publication). https://izlik.org/JA83PJ52DA

Chicago

Demirel, Sadettin, and İpek Nazlı Sinağ. 2026. “Essential Oils: A Review of Ex Vivo Studies on Aortic Smooth Muscle Contractility”. International Journal of Secondary Metabolite, no. Advanced Online Publication. https://izlik.org/JA83PJ52DA.

EndNote

Demirel S, Sinağ İN (July 1, 2026) Essential oils: A review of ex vivo studies on aortic smooth muscle contractility. International Journal of Secondary Metabolite Advanced Online Publication

IEEE

[1]S. Demirel and İ. N. Sinağ, “Essential oils: A review of ex vivo studies on aortic smooth muscle contractility”, Int. J. Sec. Metabolite, no. Advanced Online Publication, July 2026, [Online]. Available: https://izlik.org/JA83PJ52DA

ISNAD

Demirel, Sadettin - Sinağ, İpek Nazlı. “Essential Oils: A Review of Ex Vivo Studies on Aortic Smooth Muscle Contractility”. International Journal of Secondary Metabolite. Advanced Online Publication (July 1, 2026). https://izlik.org/JA83PJ52DA.

JAMA

1.Demirel S, Sinağ İN. Essential oils: A review of ex vivo studies on aortic smooth muscle contractility. Int. J. Sec. Metabolite. 2026. Available at https://izlik.org/JA83PJ52DA.

MLA

Demirel, Sadettin, and İpek Nazlı Sinağ. “Essential Oils: A Review of Ex Vivo Studies on Aortic Smooth Muscle Contractility”. International Journal of Secondary Metabolite, no. Advanced Online Publication, July 2026, https://izlik.org/JA83PJ52DA.

Vancouver

1.Sadettin Demirel, İpek Nazlı Sinağ. Essential oils: A review of ex vivo studies on aortic smooth muscle contractility. Int. J. Sec. Metabolite [Internet]. 2026 Jul. 1;(Advanced Online Publication). Available from: https://izlik.org/JA83PJ52DA