Nepeta L. is one of the important genus in the Lamiaceae family. It includes ca. 300 herbaceous species and mostly grows in Eurasia. Nepeta is represented in Turkey by 40 taxa and of these 16 are endemic. Nepeta species are commonly utilized in traditional medicine by the local people, primarily as spasmolytic, diuretic, and bronchodilator agents. As a consequence of studies on Nepeta taxa, terpenoids and flavonoids have been identified as the most common components. In this report, chemical contents of two endemic Nepeta taxa (N. viscida from Buharkent/Aydın and N. nuda L. subsp. lydiae from Altınyayla/Burdur) were presented. The main constituents were determined as α-terpineol (20.59%), trans-β-caryophyllene (9.90%) and spathulenol (9.37%) for N. viscida, and 1,8-cineole (31.31%), borneol (18.95%) and caryophyllene oxide (14.59%) for N. nuda subsp. lydiae.
This study was partly supported by Pamukkale University, Scientific Research Coordination Unit.
References
Akdeniz, M., Ertas, A., Yener, I., Firat, M., & Kolak, U. (2020). Phytochemical and biological investigations on two Nepeta species: Nepeta heliotropifolia and N. congesta subsp. cryptantha. Journal of Food Biochemistry, 44(2), e13124. https://doi.org/10.1111/jfbc.13124
Asgarpanah, J., Sarabian, S., & Ziarati, P. (2014). Essential oil of Nepeta genus (Lamiaceae) from Iran: a review. Journal of Essential Oil Research, 26(1), 1 12. https://doi.org/10.1080/10412905.2013.851040
Baser, K.H.C., Ozek, T., Tumen, G. (1995). Composition of the essential oil of Nepeta viscida Boiss. from Turkey. Journal of Essential Oil Research, 7, 569–570.
Baser, K.H.C., & Kırımer, N. (2018). Essential Oils of Anatolian Lamiaceae-An update. Natural Volatiles and Essential Oils, 5(4), 1–28.
Baser, K.H.C., Demircakmak, B., Altintas, A., & Duman, H. (1998). Composition of the essential oils of Nepeta cadmea Boiss. Journal of Essential Oil Research, 10(3), 327–328. https://doi.org/10.1080/10412905.1998.9700911
Baser, K.H.C., Kırımer, N., Kürkçüoğlu, M., & Demirci, B. (2000). Essential oils of Nepeta species growing in Turkey. Chemistry of Natural Compounds, 36(4), 356 359. https://doi.org/10.1023/A:1002832628159
Baser, K.H.C., & Özek, T. (1994). Composition of the essential oil of Nepeta caesarea Boiss. From Turkey. Journal of Essential Oil Research, 6(6), 645 646. https://doi.org/10.1080/10412905.1994.9699361
Baser, K.H.C., Özek, T., Akgül, A., & Tümen, G. (1993). Composition of the essential oil of Nepeta racemosa Lam.Journal of Essential Oil Research, 5(2), 215–217. https://doi.org/10.1080/10412905.1993.9698205
Baser, K.H.C., Oözek, T., Bemirci, B., & Tümen, G. (2001). Composition of the essential oil of Nepeta betonicifolia CA Meyer from Turkey. Journal of Essential Oil Research, 13(1), 35–36. https://doi.org/10.1080/10412905.2001.9699598
Baytop, T. (1999). Türkiye'de bitkiler ile tedavi: geçmişte ve bugün [Curing with plants in Turkey, in the past and today]. Nobel Medical Books.
Blanch, J.S., Peñuelas, J., Sardans, J., & Llusià, J. (2009). Drought, warming and soil fertilization effects on leaf volatile terpene concentrations in Pinus halepensis and Quercus ilex. Acta Physiologiae Plantarum, 31(1), 207–218. https://doi.org/10.1007/s11738-008-0221-z
Bozok, F. (2018). Herbicidal activity of Nepeta flavida essential oil. Journal of Essential Oil-Bearing Plants, 21(6), 1687–1693. https://doi.org/10.1080/0972060X.2019.1577183
Bozok, F., Cenet, M., Sezer, G., & Ulukanli, Z. (2017). Essential oil and bioherbicidal potential of the aerial parts of Nepeta nuda subsp. albiflora (Lamiaceae). Journal of Essential Oil-Bearing Plants, 20(1), 148–154. https://doi.org/10.1080/0972060X.2016.1264279
Carikci, S., (2021). Characterization of Nepeta viscida, N. nuda subsp. nuda and the Putative Hybrid N. × tmolea Essential Oils. Records of Natural Products, 15(5), 388–395. http://doi.org/10.25135/rnp.250.21.04.2033
Celep, F., & Dirmenci, T. (2017). Systematic and Biogeographic overview of Lamiaceae in Turkey. Natural Volatiles and Essential Oils, 4(4), 14–27. Retrieved from https://dergipark.org.tr/en/pub/nveo/issue/38934/454948
Celik, A., Mercan, N., Arslan, I., & Davran, H. (2008). Chemical composition and antimicrobial activity of essential oil from Nepeta cadmea. Chemistry of Natural Compounds, 44(1), 119–120. https://doi.org/10.1007/s10600-008-0036-6
El Khoury, R., Michael Jubeli, R., El Beyrouthy, M., Baillet Guffroy, A., Rizk, T., Tfayli, A., & Lteif, R. (2019). Phytochemical screening and antityrosinase activity of carvacrol, thymoquinone, and four essential oils of Lebanese plants. Journal of Cosmetic Dermatology, 18(3), 944–952. https://doi.org/10.1111/jocd.12754
Emre, İ., Kurşat, M., & Yılmaz, Ö. (2011). Some biological compounds, radical scavenging capacities and antimicrobial activities in the seeds of Nepeta italica L. and Sideritis montana L. subsp. Montana from Turkey. Grasas y Aceites, 62, 68 75. https://doi.org/10.3989/gya.033210
Formisano, C., Rigano, D., & Senatore, F. (2011). Chemical constituents and biological activities of Nepeta species. Chemistry & Biodiversity, 8(10), 1783 1818. https://doi.org/10.1002/cbdv.201000191
Gökbulut, A., & Yılmaz, G. (2020). Nepeta humilis Bentham: First evaluation of phenolic profile and radical scavenging potential. Journal of Research in Pharmacy, 24(6), 901–907. https://doi.org/10.35333/jrp.2020.249
Gomes, E.N., Allen, K.A., Zorde, M., Wu, Q., & Simon, J.E. (2020). Ethnobotany, Chemistry, and Pharmacology of African Nepeta Species. In ACS Symposium Series (pp. 219–236). American Chemical Society. https://doi.org/10.1021/bk-2020-1361.ch010
Gormez, A., Bozari, S., Yanmis, D., Gulluce, M., Agar, G., & Sahin, F. (2013). Antibacterial activity and chemical composition of essential oil obtained from Nepeta nuda against phytopathogenic bacteria. Journal of Essential Oil Research, 25(2), 149–153. https://doi.org/10.1080/10412905.2012.751060
Harley, R.M., Atkins, S., Budantsev, A.L., Cantino, P.D., Conn, B.J., Grayer, R., Harley, M.M., Kok, R., Krestovskaja, T., Morales, R., Paton, A.J., Ryding, O., & Upson, T. (2004). Labiatae. In: K, Kubitzki & J. W. Kadereit (Eds.). Families and genera of vascular plants, Vol. 7, Berlin: Springer.
İşcan, G., Köse, Y.B., Demirci, B., & Can Başer, K.H. (2011). Anticandidal activity of the essential oil of Nepeta transcaucasica Grossh. Chemistry & Biodiversity, 8(11), 2144–2148. https://doi.org/10.1002/cbdv.201100091
Jamzad, Z. (2013). A survey of Lamiaceae in the flora of Iran. Rostaniha, 14(1), 59-67. https://doi.org/10.22092/BOTANY.2013.101317
Kabalay, B., Mutlu, D., Arslan, S., Semiz, G., Kocabiyik, K. (2018, July 03-06). Chemical composition and cytotoxicity of Nepeta nuda subsp. lydiae P. H. Davis essential oil towards colon carcinoma [Paper presentation]. Abstracts Book of the 4rd International Symposium on EuroAsian Biodiversity, Kiev, Ukraine.
Kainulainen, P., Oksanen, J., Palomaki, V., Holopainen, J.K., & Holopainen, T. (1992). Effect of drought and waterlogging stress on needle monoterpenes of Picea abies. Canadian Journal of Botany, 70(8), 1613–1616. https://doi.org/10.1139/b92-203
Karakus, S., Atici, O., Kose, C., & Tiryaki, D. (2021). Antifungal effect of essential oil and different extracts obtained from Nepeta meyeri on Botrytis cinerea. Acta Scientiarum Polonorum Hortorum Cultus, 20(1), 111–122. https://doi.org/10.24326/asphc.2021.1.11
Kilic, O., Behcet, L., & Bagci, E. (2013). Essential oil compounds of three Nepeta L. taxa from Turkey and their chemotaxonomy. Asian Journal of Chemistry, 25(14), 8181–8183. https://doi.org/10.14233/ajchem.2013.15531
Kilic, O., Hayta, S., & Bagci, E. (2011). Chemical composition of essential oil of Nepeta nuda L. subsp. nuda (Lamiaceae) from Turkey. Asian Journal of Chemistry, 23(6), 2788–2790.
Kökdil, G., Kurucu, S., & Topçu, G. (1996). Composition of the essential oil of Nepeta nuda L. ssp. albiflora (Boiss.) Gams. Flavour and Fragrance Journal, 11(3), 167–169. https://doi.org/10.1002/(SICI)1099-1026(199605)11:3<167::AID-FFJ567>3.0.CO;2-A
Kökdil, G., Tanker, M., Kurucu, S., & Topçu, G. (1997). Essential oil analysis of Nepeta cilicia Boiss. Flavour and Fragrance Journal, 12(2), 99–101. https://doi.org/10.1002/(SICI)1099-1026(199703)12:2<99::AID-FFJ619>3.0.CO;2-%23
Kökdil, G., Kurucu, S., & Yıldız, A. (1998). Essential oil composition of Nepeta nuda L. ssp. nuda. Flavour and Fragrance Journal, 13(4), 233–234. https://doi.org/10.1002/(SICI)1099-1026(1998070)13:4<233::AID-FFJ730>3.0.CO;2-7
Koyuncu, O., Yaylaci, O., Öztürk, D., Potoglu Erkara, I., Savaroglu, F., Akcoskun, O., & Ardic, M. (2010). Risk categories and ethnobotanical features of the Lamiaceae taxa growing naturally in Osmaneli (Bilecik/Turkey) and environs. Biological Diversity and Conservation, 3(3), 31–45.
Li, B., Cantino, P.D., Olmstead, R.G., Bramley, G.L.C., Xiang, C.L., Ma, Z.H., Tan, Y.H., & Zhang, D.X. (2016). A large-scale chloroplast phylogeny of the Lamiaceae sheds new light on its subfamilial classification. Scientific Reports, 6(1), 1 18. https://doi.org/10.1038/srep34343
Li, B., & Olmstead, R.G. (2017). Two new subfamilies in Lamiaceae. Phytotaxa, 313(2), 222–226. https://doi.org/10.11646/phytotaxa.313.2.9
Loziené, K., Šakalyté, J., Paškevicius, A., & Venskutonis, P.R. (2008). Anti-candida activity of Thymus pulegioides (Lamiaceae) essential oils depends on the plant chemotype. Herba Polonica, 54(4), 79–92.
McElvain, S.M., & Eisenbraun, E.J. (1955). The constituents of the volatile oil of catnip. III. the structure of nepetalic acid and related compounds. Journal of the American Chemical Society, 77(6), 1599–1605. https://doi.org/10.1021/ja01611a058
Mükemre, M., Behçet, L., & Çakılcıoğlu, U. (2015). Ethnobotanical study on medicinal plants in villages of Çatak (Van-Turkey). Journal of Ethnopharmacology, 166, 361–374. https://doi.org/10.1016/j.jep.2015.03.040
Naghibi, F., Mosaddegh, M., Motamed, S.M. & Ghorbani, A. (2005). Labiatae family in folk medicine in Iran: from ethnobotany to pharmacology. Iranian Journal of Pharmaceutical Research, 4(2), 63–79.
Nuńez, R.D., & De Castro, C.O. (1992). Paleoethnobotany and archaeobotany of the Labiatae in Europe and the near East. In R. M, Harley & T, Reynolds (Eds). Advances in Labiatae Science. Kew: Royal Botanic Gardens.
Ormeño, E., Fernandez, C. (2012). Effect of soil nutrient on production and diversity of volatile terpenoids from plants. Current Bioactive Compounds, 8(1), 71 79. https://doi.org/10.2174/157340712799828188
Rattray, R.D., & Van Wyk, B.E. (2021). The botanical, chemical and ethnobotanical diversity of southern African Lamiaceae. Molecules, 26(12), 3712. https://doi.org/10.3390/molecules26123712
Sarikurkcu, C., Ceylan, O., Targan, S., & Zeljković, S.Ć. (2018). Chemical composition and biological activities of the essential oils of two endemic Nepeta species. Industrial Crops and Products, 125, 5–8. https://doi.org/10.1016/j.indcrop.2018.09.001
Semiz, G., Semiz, A., & Mercan-Doğan, N. (2018). Essential oil composition, total phenolic content, antioxidant and antibiofilm activities of four Origanum species from southeastern Turkey. International Journal of Food Properties, 21(1), 194 204. https://doi.org/10.1080/10942912.2018.1440240
Senatore, F., & Özcan, M. (2003). Composition of the essential oil of Nepeta betonicifolia CA Meyer (Lamiaceae) from Turkey. Journal of Essential Oil Research, 15(3), 200–201. https://doi.org/10.1080/10412905.2003.9712113
Sharma, A., & Cannoo, D.S. (2013). Phytochemical composition of essential oils isolated from different species of genus Nepeta of Labiatae family: a review. Pharmacophore, 4(6), 181–211.
Sharma, A., Cooper, R., Bhardwaj, G., & Cannoo, D.S. (2021). The genus Nepeta: Traditional uses, phytochemicals and pharmacological properties. Journal of Ethnopharmacology, 268, 113679. https://doi.org/10.1016/j.jep.2020.113679
Tepe, B., Daferera, D., Tepe, A.S., Polissiou, M., & Sökmen, A. (2007). Antioxidant activity of the essential oil and various extracts of Nepeta flavida Hub.-Mor. from Turkey. Food Chemistry, 103(4), 1358–1364. https://doi.org/10.1016/j.foodchem.2006.10.049
Tingey, D.T., Manning, M., Grothaus, L.C., Burns, W.F. (1980). Influence of light and temperature on monoterpene emission rates from Slash Pine. Plant Physiology., 65(5), 797–801. https://doi.org/10.1104/pp.65.5.797
Tümen, G., Baser, K.H.C., Kürkçüoglu, M., Demirci, B., & Yildiz, B. (1999). Composition of the essential oil of Nepeta trachonitica post from Turkey. Journal of Essential Oil Research, 11(1), 21–22. https://doi.org/10.1080/10412905.1999.9701059
Yu, H., Holopainen, J.K., Kivimäenpää, M., Virtanen, A., & Blande, J.D. (2021). Potential of climate change and herbivory to affect the release and atmospheric reactions of BVOCs from Boreal and Subarctic forests. Molecules, 26(8), 2283. https://doi.org/10.3390/molecules26082283
Zengin, G., Mahomoodally, M.F., Aktumsek, A., Jekő, J., Cziáky, Z., Rodrigues, M. J., Custodio, L., Polat, R., Cakiloglu, U., Ayna, A., Gallo, M., Montesano, D & Picot-Allain, C. (2021). Chemical profiling and biological evaluation of Nepeta baytopii extracts and essential oil: An endemic plant from Turkey. Plants, 10(6), 1176. https://doi.org/10.3390/plants10061176
Essential oil composition of two endemic Nepeta L. (Lamiaceae) taxa from Southwestern Turkey
Year 2022,
Volume: 9 Issue: 2, 158 - 165, 15.06.2022
Nepeta L. is one of the important genus in the Lamiaceae family. It includes ca. 300 herbaceous species and mostly grows in Eurasia. Nepeta is represented in Turkey by 40 taxa and of these 16 are endemic. Nepeta species are commonly utilized in traditional medicine by the local people, primarily as spasmolytic, diuretic, and bronchodilator agents. As a consequence of studies on Nepeta taxa, terpenoids and flavonoids have been identified as the most common components. In this report, chemical contents of two endemic Nepeta taxa (N. viscida from Buharkent/Aydın and N. nuda L. subsp. lydiae from Altınyayla/Burdur) were presented. The main constituents were determined as α-terpineol (20.59%), trans-β-caryophyllene (9.90%) and spathulenol (9.37%) for N. viscida, and 1,8-cineole (31.31%), borneol (18.95%) and caryophyllene oxide (14.59%) for N. nuda subsp. lydiae.
Akdeniz, M., Ertas, A., Yener, I., Firat, M., & Kolak, U. (2020). Phytochemical and biological investigations on two Nepeta species: Nepeta heliotropifolia and N. congesta subsp. cryptantha. Journal of Food Biochemistry, 44(2), e13124. https://doi.org/10.1111/jfbc.13124
Asgarpanah, J., Sarabian, S., & Ziarati, P. (2014). Essential oil of Nepeta genus (Lamiaceae) from Iran: a review. Journal of Essential Oil Research, 26(1), 1 12. https://doi.org/10.1080/10412905.2013.851040
Baser, K.H.C., Ozek, T., Tumen, G. (1995). Composition of the essential oil of Nepeta viscida Boiss. from Turkey. Journal of Essential Oil Research, 7, 569–570.
Baser, K.H.C., & Kırımer, N. (2018). Essential Oils of Anatolian Lamiaceae-An update. Natural Volatiles and Essential Oils, 5(4), 1–28.
Baser, K.H.C., Demircakmak, B., Altintas, A., & Duman, H. (1998). Composition of the essential oils of Nepeta cadmea Boiss. Journal of Essential Oil Research, 10(3), 327–328. https://doi.org/10.1080/10412905.1998.9700911
Baser, K.H.C., Kırımer, N., Kürkçüoğlu, M., & Demirci, B. (2000). Essential oils of Nepeta species growing in Turkey. Chemistry of Natural Compounds, 36(4), 356 359. https://doi.org/10.1023/A:1002832628159
Baser, K.H.C., & Özek, T. (1994). Composition of the essential oil of Nepeta caesarea Boiss. From Turkey. Journal of Essential Oil Research, 6(6), 645 646. https://doi.org/10.1080/10412905.1994.9699361
Baser, K.H.C., Özek, T., Akgül, A., & Tümen, G. (1993). Composition of the essential oil of Nepeta racemosa Lam.Journal of Essential Oil Research, 5(2), 215–217. https://doi.org/10.1080/10412905.1993.9698205
Baser, K.H.C., Oözek, T., Bemirci, B., & Tümen, G. (2001). Composition of the essential oil of Nepeta betonicifolia CA Meyer from Turkey. Journal of Essential Oil Research, 13(1), 35–36. https://doi.org/10.1080/10412905.2001.9699598
Baytop, T. (1999). Türkiye'de bitkiler ile tedavi: geçmişte ve bugün [Curing with plants in Turkey, in the past and today]. Nobel Medical Books.
Blanch, J.S., Peñuelas, J., Sardans, J., & Llusià, J. (2009). Drought, warming and soil fertilization effects on leaf volatile terpene concentrations in Pinus halepensis and Quercus ilex. Acta Physiologiae Plantarum, 31(1), 207–218. https://doi.org/10.1007/s11738-008-0221-z
Bozok, F. (2018). Herbicidal activity of Nepeta flavida essential oil. Journal of Essential Oil-Bearing Plants, 21(6), 1687–1693. https://doi.org/10.1080/0972060X.2019.1577183
Bozok, F., Cenet, M., Sezer, G., & Ulukanli, Z. (2017). Essential oil and bioherbicidal potential of the aerial parts of Nepeta nuda subsp. albiflora (Lamiaceae). Journal of Essential Oil-Bearing Plants, 20(1), 148–154. https://doi.org/10.1080/0972060X.2016.1264279
Carikci, S., (2021). Characterization of Nepeta viscida, N. nuda subsp. nuda and the Putative Hybrid N. × tmolea Essential Oils. Records of Natural Products, 15(5), 388–395. http://doi.org/10.25135/rnp.250.21.04.2033
Celep, F., & Dirmenci, T. (2017). Systematic and Biogeographic overview of Lamiaceae in Turkey. Natural Volatiles and Essential Oils, 4(4), 14–27. Retrieved from https://dergipark.org.tr/en/pub/nveo/issue/38934/454948
Celik, A., Mercan, N., Arslan, I., & Davran, H. (2008). Chemical composition and antimicrobial activity of essential oil from Nepeta cadmea. Chemistry of Natural Compounds, 44(1), 119–120. https://doi.org/10.1007/s10600-008-0036-6
El Khoury, R., Michael Jubeli, R., El Beyrouthy, M., Baillet Guffroy, A., Rizk, T., Tfayli, A., & Lteif, R. (2019). Phytochemical screening and antityrosinase activity of carvacrol, thymoquinone, and four essential oils of Lebanese plants. Journal of Cosmetic Dermatology, 18(3), 944–952. https://doi.org/10.1111/jocd.12754
Emre, İ., Kurşat, M., & Yılmaz, Ö. (2011). Some biological compounds, radical scavenging capacities and antimicrobial activities in the seeds of Nepeta italica L. and Sideritis montana L. subsp. Montana from Turkey. Grasas y Aceites, 62, 68 75. https://doi.org/10.3989/gya.033210
Formisano, C., Rigano, D., & Senatore, F. (2011). Chemical constituents and biological activities of Nepeta species. Chemistry & Biodiversity, 8(10), 1783 1818. https://doi.org/10.1002/cbdv.201000191
Gökbulut, A., & Yılmaz, G. (2020). Nepeta humilis Bentham: First evaluation of phenolic profile and radical scavenging potential. Journal of Research in Pharmacy, 24(6), 901–907. https://doi.org/10.35333/jrp.2020.249
Gomes, E.N., Allen, K.A., Zorde, M., Wu, Q., & Simon, J.E. (2020). Ethnobotany, Chemistry, and Pharmacology of African Nepeta Species. In ACS Symposium Series (pp. 219–236). American Chemical Society. https://doi.org/10.1021/bk-2020-1361.ch010
Gormez, A., Bozari, S., Yanmis, D., Gulluce, M., Agar, G., & Sahin, F. (2013). Antibacterial activity and chemical composition of essential oil obtained from Nepeta nuda against phytopathogenic bacteria. Journal of Essential Oil Research, 25(2), 149–153. https://doi.org/10.1080/10412905.2012.751060
Harley, R.M., Atkins, S., Budantsev, A.L., Cantino, P.D., Conn, B.J., Grayer, R., Harley, M.M., Kok, R., Krestovskaja, T., Morales, R., Paton, A.J., Ryding, O., & Upson, T. (2004). Labiatae. In: K, Kubitzki & J. W. Kadereit (Eds.). Families and genera of vascular plants, Vol. 7, Berlin: Springer.
İşcan, G., Köse, Y.B., Demirci, B., & Can Başer, K.H. (2011). Anticandidal activity of the essential oil of Nepeta transcaucasica Grossh. Chemistry & Biodiversity, 8(11), 2144–2148. https://doi.org/10.1002/cbdv.201100091
Jamzad, Z. (2013). A survey of Lamiaceae in the flora of Iran. Rostaniha, 14(1), 59-67. https://doi.org/10.22092/BOTANY.2013.101317
Kabalay, B., Mutlu, D., Arslan, S., Semiz, G., Kocabiyik, K. (2018, July 03-06). Chemical composition and cytotoxicity of Nepeta nuda subsp. lydiae P. H. Davis essential oil towards colon carcinoma [Paper presentation]. Abstracts Book of the 4rd International Symposium on EuroAsian Biodiversity, Kiev, Ukraine.
Kainulainen, P., Oksanen, J., Palomaki, V., Holopainen, J.K., & Holopainen, T. (1992). Effect of drought and waterlogging stress on needle monoterpenes of Picea abies. Canadian Journal of Botany, 70(8), 1613–1616. https://doi.org/10.1139/b92-203
Karakus, S., Atici, O., Kose, C., & Tiryaki, D. (2021). Antifungal effect of essential oil and different extracts obtained from Nepeta meyeri on Botrytis cinerea. Acta Scientiarum Polonorum Hortorum Cultus, 20(1), 111–122. https://doi.org/10.24326/asphc.2021.1.11
Kilic, O., Behcet, L., & Bagci, E. (2013). Essential oil compounds of three Nepeta L. taxa from Turkey and their chemotaxonomy. Asian Journal of Chemistry, 25(14), 8181–8183. https://doi.org/10.14233/ajchem.2013.15531
Kilic, O., Hayta, S., & Bagci, E. (2011). Chemical composition of essential oil of Nepeta nuda L. subsp. nuda (Lamiaceae) from Turkey. Asian Journal of Chemistry, 23(6), 2788–2790.
Kökdil, G., Kurucu, S., & Topçu, G. (1996). Composition of the essential oil of Nepeta nuda L. ssp. albiflora (Boiss.) Gams. Flavour and Fragrance Journal, 11(3), 167–169. https://doi.org/10.1002/(SICI)1099-1026(199605)11:3<167::AID-FFJ567>3.0.CO;2-A
Kökdil, G., Tanker, M., Kurucu, S., & Topçu, G. (1997). Essential oil analysis of Nepeta cilicia Boiss. Flavour and Fragrance Journal, 12(2), 99–101. https://doi.org/10.1002/(SICI)1099-1026(199703)12:2<99::AID-FFJ619>3.0.CO;2-%23
Kökdil, G., Kurucu, S., & Yıldız, A. (1998). Essential oil composition of Nepeta nuda L. ssp. nuda. Flavour and Fragrance Journal, 13(4), 233–234. https://doi.org/10.1002/(SICI)1099-1026(1998070)13:4<233::AID-FFJ730>3.0.CO;2-7
Koyuncu, O., Yaylaci, O., Öztürk, D., Potoglu Erkara, I., Savaroglu, F., Akcoskun, O., & Ardic, M. (2010). Risk categories and ethnobotanical features of the Lamiaceae taxa growing naturally in Osmaneli (Bilecik/Turkey) and environs. Biological Diversity and Conservation, 3(3), 31–45.
Li, B., Cantino, P.D., Olmstead, R.G., Bramley, G.L.C., Xiang, C.L., Ma, Z.H., Tan, Y.H., & Zhang, D.X. (2016). A large-scale chloroplast phylogeny of the Lamiaceae sheds new light on its subfamilial classification. Scientific Reports, 6(1), 1 18. https://doi.org/10.1038/srep34343
Li, B., & Olmstead, R.G. (2017). Two new subfamilies in Lamiaceae. Phytotaxa, 313(2), 222–226. https://doi.org/10.11646/phytotaxa.313.2.9
Loziené, K., Šakalyté, J., Paškevicius, A., & Venskutonis, P.R. (2008). Anti-candida activity of Thymus pulegioides (Lamiaceae) essential oils depends on the plant chemotype. Herba Polonica, 54(4), 79–92.
McElvain, S.M., & Eisenbraun, E.J. (1955). The constituents of the volatile oil of catnip. III. the structure of nepetalic acid and related compounds. Journal of the American Chemical Society, 77(6), 1599–1605. https://doi.org/10.1021/ja01611a058
Mükemre, M., Behçet, L., & Çakılcıoğlu, U. (2015). Ethnobotanical study on medicinal plants in villages of Çatak (Van-Turkey). Journal of Ethnopharmacology, 166, 361–374. https://doi.org/10.1016/j.jep.2015.03.040
Naghibi, F., Mosaddegh, M., Motamed, S.M. & Ghorbani, A. (2005). Labiatae family in folk medicine in Iran: from ethnobotany to pharmacology. Iranian Journal of Pharmaceutical Research, 4(2), 63–79.
Nuńez, R.D., & De Castro, C.O. (1992). Paleoethnobotany and archaeobotany of the Labiatae in Europe and the near East. In R. M, Harley & T, Reynolds (Eds). Advances in Labiatae Science. Kew: Royal Botanic Gardens.
Ormeño, E., Fernandez, C. (2012). Effect of soil nutrient on production and diversity of volatile terpenoids from plants. Current Bioactive Compounds, 8(1), 71 79. https://doi.org/10.2174/157340712799828188
Rattray, R.D., & Van Wyk, B.E. (2021). The botanical, chemical and ethnobotanical diversity of southern African Lamiaceae. Molecules, 26(12), 3712. https://doi.org/10.3390/molecules26123712
Sarikurkcu, C., Ceylan, O., Targan, S., & Zeljković, S.Ć. (2018). Chemical composition and biological activities of the essential oils of two endemic Nepeta species. Industrial Crops and Products, 125, 5–8. https://doi.org/10.1016/j.indcrop.2018.09.001
Semiz, G., Semiz, A., & Mercan-Doğan, N. (2018). Essential oil composition, total phenolic content, antioxidant and antibiofilm activities of four Origanum species from southeastern Turkey. International Journal of Food Properties, 21(1), 194 204. https://doi.org/10.1080/10942912.2018.1440240
Senatore, F., & Özcan, M. (2003). Composition of the essential oil of Nepeta betonicifolia CA Meyer (Lamiaceae) from Turkey. Journal of Essential Oil Research, 15(3), 200–201. https://doi.org/10.1080/10412905.2003.9712113
Sharma, A., & Cannoo, D.S. (2013). Phytochemical composition of essential oils isolated from different species of genus Nepeta of Labiatae family: a review. Pharmacophore, 4(6), 181–211.
Sharma, A., Cooper, R., Bhardwaj, G., & Cannoo, D.S. (2021). The genus Nepeta: Traditional uses, phytochemicals and pharmacological properties. Journal of Ethnopharmacology, 268, 113679. https://doi.org/10.1016/j.jep.2020.113679
Tepe, B., Daferera, D., Tepe, A.S., Polissiou, M., & Sökmen, A. (2007). Antioxidant activity of the essential oil and various extracts of Nepeta flavida Hub.-Mor. from Turkey. Food Chemistry, 103(4), 1358–1364. https://doi.org/10.1016/j.foodchem.2006.10.049
Tingey, D.T., Manning, M., Grothaus, L.C., Burns, W.F. (1980). Influence of light and temperature on monoterpene emission rates from Slash Pine. Plant Physiology., 65(5), 797–801. https://doi.org/10.1104/pp.65.5.797
Tümen, G., Baser, K.H.C., Kürkçüoglu, M., Demirci, B., & Yildiz, B. (1999). Composition of the essential oil of Nepeta trachonitica post from Turkey. Journal of Essential Oil Research, 11(1), 21–22. https://doi.org/10.1080/10412905.1999.9701059
Yu, H., Holopainen, J.K., Kivimäenpää, M., Virtanen, A., & Blande, J.D. (2021). Potential of climate change and herbivory to affect the release and atmospheric reactions of BVOCs from Boreal and Subarctic forests. Molecules, 26(8), 2283. https://doi.org/10.3390/molecules26082283
Zengin, G., Mahomoodally, M.F., Aktumsek, A., Jekő, J., Cziáky, Z., Rodrigues, M. J., Custodio, L., Polat, R., Cakiloglu, U., Ayna, A., Gallo, M., Montesano, D & Picot-Allain, C. (2021). Chemical profiling and biological evaluation of Nepeta baytopii extracts and essential oil: An endemic plant from Turkey. Plants, 10(6), 1176. https://doi.org/10.3390/plants10061176
Semiz, G., Günal, B., & Armağan, M. (2022). Essential oil composition of two endemic Nepeta L. (Lamiaceae) taxa from Southwestern Turkey. International Journal of Secondary Metabolite, 9(2), 158-165. https://doi.org/10.21448/ijsm.1078429