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Yıl 2021, Cilt: 2 Sayı: 1, 36 - 48, 15.04.2021

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Proje Numarası

No.

Kaynakça

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  • 4. Commission CA. Revised codex standard for honey. Codex Stan. 2001:12-1981.
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  • 6. da C Azeredo L, Azeredo M, De Souza S, Dutra V. Protein contents and physicochemical properties in honey samples of Apis mellifera of different floral origins. Food chemistry. 2003;80(2):249-254.
  • 7. Iglesias MT, De Lorenzo C, Polo MdC, Martín-Álvarez PJ, Pueyo E. Usefulness of amino acid composition to discriminate between honeydew and floral honeys. Application to honeys from a small geographic area. Journal of agricultural and food chemistry. 2004;52(1):84-89.
  • 8. Bogdanov S, Jurendic T, Sieber R, Gallmann P. Honey for nutrition and health: a review. Journal of the American College of Nutrition. 2008;27(6):677-689.
  • 9. Escuredo O, Míguez M, Fernández-González M, Carmen Seijo M. Nutritional value and antioxidant activity of honeys produced in a European Atlantic area. Food Chemistry. 2013;138(2):851-856.
  • 10. Escuredo O, Dobre I, Fernández-González M, Seijo MC. Contribution of botanical origin and sugar composition of honeys on the crystallization phenomenon. Food chemistry. 2014;149:84-90.
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  • 18. Gheldof N, Wang X-H, Engeseth NJ. Identification and quantification of antioxidant components of honeys from various floral sources. Journal of agricultural and food chemistry. 2002;50(21):5870-5877.
  • 19. Erejuwa OO, Sulaiman SA, Ab Wahab MS. Honey: a novel antioxidant. Molecules. 2012;17(4):4400-4423.
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Overview of Apitherapy Products: Anti-Cancer Effects of Bee Venom Used in Apitherapy

Yıl 2021, Cilt: 2 Sayı: 1, 36 - 48, 15.04.2021

Öz

While Brazil and the United States of America are in the first place in world Apitherapy research, our country is in the fifth place after Japan and China. While the studies on apitherapy are continuing rapidly in the world, it has started to become widespread in our country especially in 2014 with the regulation of traditional and complementary medicine practices, and Apitherapy units and application centers have started to be established. Apitherapy is the use of bee products to protect and improve health, to strengthen the immune system and to complement the treatment process of some diseases. While bee products such as honey, propolis, bee pollen have been known and used for a long time, studies on apilarnil, royal jelly and bee venom have started to increase in recent years. These products have been used both as foodstuffs and as a source of healing from wound healing to anticancer effect for many years due to their rich content. With scientific studies, the interest in apitherapy products has increased even more.
Cancer is known as the leading cause of death in our country and all over the world. Side effects, costs, etc. Such adverse conditions have led researchers to research natural treatment methods. These natural treatments are used to increase the effectiveness of existing traditional treatments. In this review, literature information about Apitherapy, which is one of the traditional and complementary medicine applications, chemical content and physiological effects of bee products, is given and the therapeutic effect of bee venom on cancer is mentioned. Studies on the anticancer activity of bee venom in almost all types of cancer have been conducted and promising results have been obtained. This situation indicates that this apitherapeutic product will take place as a supplement in cancer treatment in the near future.

Destekleyen Kurum

There are no individuals or organizations that financially support the study.

Proje Numarası

No.

Teşekkür

No.

Kaynakça

  • 1. Yeşilada E. [Apiterapi Arıyla Gelen Şifa]. 1 ed. İstanbul: Hayykitap; 2015.
  • 2. Schmidt JO. Bee Products. In: Mizrahi A, Lensky Y, eds. Bee Products: Properties, Applications, and Apitherapy. Boston, MA: Springer US; 1997:15-26.
  • 3. Enstitüsü TS. TSE 3036 Bal Standardı. In. Ankara2010.
  • 4. Commission CA. Revised codex standard for honey. Codex Stan. 2001:12-1981.
  • 5. Ferreira IC, Aires E, Barreira JC, Estevinho LM. Antioxidant activity of Portuguese honey samples: Different contributions of the entire honey and phenolic extract. Food Chemistry. 2009;114(4):1438-1443.
  • 6. da C Azeredo L, Azeredo M, De Souza S, Dutra V. Protein contents and physicochemical properties in honey samples of Apis mellifera of different floral origins. Food chemistry. 2003;80(2):249-254.
  • 7. Iglesias MT, De Lorenzo C, Polo MdC, Martín-Álvarez PJ, Pueyo E. Usefulness of amino acid composition to discriminate between honeydew and floral honeys. Application to honeys from a small geographic area. Journal of agricultural and food chemistry. 2004;52(1):84-89.
  • 8. Bogdanov S, Jurendic T, Sieber R, Gallmann P. Honey for nutrition and health: a review. Journal of the American College of Nutrition. 2008;27(6):677-689.
  • 9. Escuredo O, Míguez M, Fernández-González M, Carmen Seijo M. Nutritional value and antioxidant activity of honeys produced in a European Atlantic area. Food Chemistry. 2013;138(2):851-856.
  • 10. Escuredo O, Dobre I, Fernández-González M, Seijo MC. Contribution of botanical origin and sugar composition of honeys on the crystallization phenomenon. Food chemistry. 2014;149:84-90.
  • 11. Cuevas-Glory LF, Pino JA, Santiago LS, Sauri-Duch E. A review of volatile analytical methods for determining the botanical origin of honey. Food Chemistry. 2007;103(3):1032-1043.
  • 12. Ulusoy E. Bal ve apiterapi. Uludağ Arıcılık Dergisi. 2012;12(3):89-97.
  • 13. Efem S. Clinical observations on the wound healing properties of honey. British journal of Surgery. 1988;75(7):679-681.
  • 14. Ali A, Chowdhury M, Al Humayyd M. Inhibitory effect of natural honey on Helicobacter pylori. Tropical gastroenterology: official journal of the Digestive Diseases Foundation. 1991;12(3):139-143.
  • 15. Mandal MD, Mandal S. Honey: its medicinal property and antibacterial activity. Asian Pacific journal of tropical biomedicine. 2011;1(2):154-160.
  • 16. Cianciosi D, Forbes-Hernández TY, Afrin S, et al. Phenolic compounds in honey and their associated health benefits: A review. Molecules. 2018;23(9):2322.
  • 17. Al-Mamary M, Al-Meeri A, Al-Habori M. Antioxidant activities and total phenolics of different types of honey. Nutrition Research. 2002;22(9):1041-1047.
  • 18. Gheldof N, Wang X-H, Engeseth NJ. Identification and quantification of antioxidant components of honeys from various floral sources. Journal of agricultural and food chemistry. 2002;50(21):5870-5877.
  • 19. Erejuwa OO, Sulaiman SA, Ab Wahab MS. Honey: a novel antioxidant. Molecules. 2012;17(4):4400-4423.
  • 20. Poljsak B, Šuput D, Milisav I. Achieving the balance between ROS and antioxidants: when to use the synthetic antioxidants. Oxidative medicine and cellular longevity. 2013;2013.
  • 21. Molan PC. Potential of honey in the treatment of wounds and burns. American journal of clinical dermatology. 2001;2(1):13-19.
  • 22. Gómez-Caravaca A, Gómez-Romero M, Arráez-Román D, Segura-Carretero A, Fernández-Gutiérrez A. Advances in the analysis of phenolic compounds in products derived from bees. Journal of Pharmaceutical and Biomedical Analysis. 2006;41(4):1220-1234.
  • 23. Estevinho L, Pereira AP, Moreira L, Dias LG, Pereira E. Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey. Food Chem Toxicol. 2008;46(12):3774-3779.
  • 24. Alvarez-Suarez JM, Tulipani S, Romandini S, Bertoli E, Battino M. Contribution of honey in nutrition and human health: a review. Mediterranean Journal of Nutrition and Metabolism. 2010;3(1):15-23.
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  • 109. Alonezi S, Tusiimire J, Wallace J, et al. Metabolomic Profiling of the Synergistic Effects of Melittin in Combination with Cisplatin on Ovarian Cancer Cells. Metabolites. 2017;7(2).
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  • 111. Park MH, Choi MS, Kwak DH, et al. Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF-kappaB. Prostate. 2011;71(8):801-812.
  • 112. Ceremuga M, Stela M, Janik E, et al. Melittin—A Natural Peptide from Bee Venom Which Induces Apoptosis in Human Leukaemia Cells. Biomolecules. 2020;10(2):247.
  • 113. Jang MH, Shin MC, Lim S, et al. Bee venom induces apoptosis and inhibits expression of cyclooxygenase-2 mRNA in human lung cancer cell line NCI-H1299. J Pharmacol Sci. 2003;91(2):95-104.
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Toplam 114 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Geleneksel, Tamamlayıcı ve Bütünleştirici Tıp
Bölüm Derlemeler
Yazarlar

Fatma Şengül 0000-0002-7097-6266

Hüsamettin Vatansev 0000-0002-0230-3414

Proje Numarası No.
Yayımlanma Tarihi 15 Nisan 2021
Gönderilme Tarihi 16 Aralık 2020
Yayımlandığı Sayı Yıl 2021 Cilt: 2 Sayı: 1

Kaynak Göster

APA Şengül, F., & Vatansev, H. (2021). Overview of Apitherapy Products: Anti-Cancer Effects of Bee Venom Used in Apitherapy. International Journal of Traditional and Complementary Medicine Research, 2(1), 36-48.

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