Türkiye'deki Yetişkinlerde BioNTech mRNA ve Sinovac Aşılarının Olumsuz Etkilerinin Karşılaştırılması

Yıl 2023, Cilt: 8 Sayı: 2, 395 - 400, 21.06.2023

Sevil Yılmaz , Perihan Çetin , Leyla Khorshid , Duygu Bayraktar

Öz

Amaç: Bu çalışmanın amacı, Türkiye'deki yetişkinlerde uygulanan Pfizer-BioNTech mRNA and Sinovac-CoronaVac -CoronaVac aşılarının yan etkilerini karşılaştırmaktır.

Gereç ve Yöntem: Bu araştırma kesitsel bir çalışmadır. Araştırmanın örneklemini Pfizer- BioNTech grubunda 95, Sinovac-CoronaVac grubunda 92 olmak üzere aşı için gelen 187 yetişkin oluşturdu. Bir hastanede aşılanan bireylere Görsel Analog Skala (VAS) ve kişisel bilgi anketi uygulandı. Aşıdan 6,12 ve 24 saat sonra herhangi bir yan etki olup olmadığı soruldu.

Bulgular: En yaygın lokal yan etki enjeksiyon bölgesinde ağrıydı, ancak en sık sistemik yan etkiler her iki grupta da halsizlik ve baş ağrısıydı. Pfizer-BioNTech aşısı ile aşılanan katılımcılarımızın çoğu (%87,4) ve Sinovac-CoronaVac alanların yaklaşık yarısı (%48,9) yan etki bildirdi. Enjeksiyon bölgesinde hissedilen ağrı Pfizer-BioNTech grubunda %86,3, Sinovac-CoronaVac grubunda %44,6’dır. Hem Pfizer-BioNTech hem de Sinovac- CoronaVac aşıları ile aşılanan katılımcılarda en az ağrı şiddeti 24. saat içinde görüldü.

Sonuç: Enjeksiyon bölgesindeki ağrı düzeyi Pfizer-BioNTech aşısında Sinovac- CoronaVac aşısına göre daha yüksektir. Çalışmamızda her iki aşıda da en fazla sistemik yan etki halsizlik ve baş ağrısı olmuştur.

Anahtar Kelimeler

Hemşire, yan etki, Pfizer-BioNTech, Sinovac-CoronaVac, aşı, ağrı

Comparison of Adverse Effects of BioNTech mRNA and Sinovac Vaccines in Adults in Turkey

Öz

Objective: The aim of this study is to compare the side effects of Pfizer-BioNTech mRNA and Sinovac-CoronaVac vaccines administered in adults in Turkey.

Material and Method: This is a cross-sectional study. The study sample consisted of 187 adults, 95 in the Pfizer-BioNTech group and 92 in the Sinovac-CoronaVac group, who came for vaccination. A Visual Analogue Scale (VAS) and a questionnaire were applied to vaccinated individuals in a hospital. They were asked about any adverse effects at 6, 12 and 24 hours post-vaccination.

Results: The most common local adverse effect was pain at the injection site, but the most frequent systemic adverse effects were weakness and headache in both groups. Most (87.4%) of our participants who were vaccinated with the Pfizer-BioNTech vaccine and nearly half (48.9%) of those who received Sinovac-CoronaVac reported adverse effects. Pain felt at the injection site was 86.3% in the Pfizer-BioNTech group and 44.6% in the Sinovac-CoronaVac group. The least pain intensity in participants who were vaccinated with both Pfizer-BioNTech and Sinovac-CoronaVac vaccines was seen in the 24 hours.

Conclusion: The pain level at the injection site after Pfizer-BioNTech was higher than the Sinovac-CoronaVac vaccine. In our study the most systemic adverse effects with both vaccines were weakness and headache.

Anahtar Kelimeler

Nursing, adverse effects, Pfizer-BioNTech, Sinovac-CoronaVac, vaccines, pain

Kaynakça

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