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Factors Associated with Post-COVID Syndrome Three Months After COVID-19

Year 2024, Volume: 15 Issue: 52, 41 - 47, 02.09.2024
https://doi.org/10.17944/interdiscip.1412206

Abstract

Objective: Post-COVID Syndrome has been defined as a syndrome with chronic fatigue and psychiatric problems continue after COVID-19. In this study, it was aimed to evaluate patients' health-related quality of life standards 3 months after COVID-19 diagnosis.
Method: In this study, the psychosocial status and quality of life standards of patients, who were older than 18 years old and followed up due to COVID-19 in the outpatient clinic, ward, or intensive care unit of a university hospital, were assesed by the short form-36 scoring system.
Results: Of 67 patients, 57 were followed up and treated at home, nine were admitted to the ward, and one was admitted to the the intensive care unit. Short form-36 test scores of women patients, patients aged over 65, had at least one comorbid disease, and inpatient treatments during acute infection were found to be statistically significantly lower.
Conclusion: Gender, advanced age, presence of comorbidity, and history of hospitalization were determined as risk factors for Post-COVID Syndrome.

Ethical Statement

The study protocol was initiated with the approval of the ethics committee of a university hospital at the meeting numbered 143 on 20.10.2021 with the decision number 20.

References

  • COVID-19. JAMA. 2020;324(6):603-605. https://doi.org/10.1001/jama.2020.12603
  • Moldofsky H, Patcai J. Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study. BMC Neurol. 2011;11:37. https://doi.org/10.1186/1471-2377-11-37
  • Disease Manifestations and Complications: CDC & IDSA 2022: Post COVID/Long COVID [cited 2022 04.06.2020]. https://www.idsociety.org/covid-19-real-time-learning-network/disease-manifestations--complications/post-covid-syndrome.
  • Halpin SJ, McIvor C, Whyatt G, et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation. J Med Virol. 2021;93(2):1013-22. https://doi.org/10.1002/jmv.26368
  • Kamal M, Abo Omirah M, Hussein A, Saeed H. Assessment and characterisation of post-COVID-19 manifestations. Int J Clin Pract. 2021;75(3):e13746. https://doi.org/10.1111/ijcp.13746
  • Han Q, Zheng B, Daines L, Sheikh A. Long-Term Sequelae of COVID-19: A Systematic Review and Meta-Analysis of One-Year Follow-Up Studies on Post-COVID Symptoms. Pathogens. 2022;11(2):269. https://doi.org/10.3390/pathogens11020269
  • Huang L, Yao Q, Gu X, et al. 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study. Lancet. 2021;398(10302):747-58. https://doi.org/10.1016/S0140-6736(21)01755-4
  • Su Y, Yuan D, Chen DG, et al. Multiple early factors anticipate post-acute COVID-19 sequelae. Cell. 2022;185(5):881-895.e20.
  • Fernández-de-Las-Peñas C, Guijarro C, Torres-Macho J, et al. Diabetes and the Risk of Long-term Post-COVID Symptoms. Diabetes. 2021;70(12):2917-292. https://doi.org/10.2337/db21-0329
  • Pavli A, Theodoridou M, Maltezou HC. Post-COVID Syndrome: Incidence, Clinical Spectrum, and Challenges for Primary Healthcare Professionals. Arch Med Res. 2021 Aug;52(6):575-581. https://doi.org/10.1016/j.arcmed.2021.03.010
  • Tleyjeh IM, Saddik B, AlSwaidan N, et al. Prevalence and predictors of Post-Acute COVID-19 Syndrome (PACS) after hospital discharge: A cohort study with 4 months median follow-up. PLoS One. 2021;16(12):e0260568. https://doi.org/10.1371/journal.pone.0260568
  • Anjana NKN, Annie TT, Siba S, Meenu MS, Chintha S, Anish TSN. Manifestations and risk factors of post COVID syndrome among COVID-19 patients presented with minimal symptoms - A study from Kerala, India. J Family Med Prim Care. 2021;10(11):4023-4029. https://doi.org/10.4103/jfmpc.jfmpc_851_21
  • Subramanian A, Nirantharakumar K, Hughes S, et al. Symptoms and risk factors for long COVID in non-hospitalized adults. Nat Med. 2022;28(8):1706-14. https://doi.org/10.1038/s41591-022-01909-w
  • Cirulli ET, Schiabor Barrett KM, Riffle S, et al. Long-term COVID-19 symptoms in a large unselected population. medRxiv. 2020.10.07.20208702. https://doi.org/10.1101/2020.10.07.20208702
  • Mahmoud N, Radwan N, Alkattan A, et al. Post-COVID-19 syndrome: nature of symptoms and associated factors. Z Gesundh Wiss. 2023 Jan 3:1-6.
  • Aminian A, Bena J, Pantalone KM, et al. Association of obesity with postacute sequelae of COVID-19. Diabetes Obes Metab. 2021;23(9):2183-8. https://doi.org/10.1111/dom.14454
  • Boscolo-Rizzo P, Guida F, Polesel J, et al. Sequelae in adults at 12 months after mild-to-moderate coronavirus disease 2019 (COVID-19). Int Forum Allergy Rhinol. 2021;11(12):1685-8. https://doi.org/10.1002/alr.22832
  • Maestre-Muniz MM, Arias A, Mata-Vazquez E, et al. Long-Term Outcomes of Patients with Coronavirus Disease 2019 at One Year after Hospital Discharge. J Clin Med. 2021;10(13):2945. https://doi.org/10.3390/jcm10132945
  • Zhang X, Wang F, Shen Y, et al. Symptoms and Health Outcomes Among Survivors of COVID-19 Infection 1 Year After Discharge From Hospitals in Wuhan, China. JAMA Netw Open. 2021;4(9):e2127403. https://doi.org/10.1001/jamanetworkopen.2021.27403a
Year 2024, Volume: 15 Issue: 52, 41 - 47, 02.09.2024
https://doi.org/10.17944/interdiscip.1412206

Abstract

References

  • COVID-19. JAMA. 2020;324(6):603-605. https://doi.org/10.1001/jama.2020.12603
  • Moldofsky H, Patcai J. Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study. BMC Neurol. 2011;11:37. https://doi.org/10.1186/1471-2377-11-37
  • Disease Manifestations and Complications: CDC & IDSA 2022: Post COVID/Long COVID [cited 2022 04.06.2020]. https://www.idsociety.org/covid-19-real-time-learning-network/disease-manifestations--complications/post-covid-syndrome.
  • Halpin SJ, McIvor C, Whyatt G, et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation. J Med Virol. 2021;93(2):1013-22. https://doi.org/10.1002/jmv.26368
  • Kamal M, Abo Omirah M, Hussein A, Saeed H. Assessment and characterisation of post-COVID-19 manifestations. Int J Clin Pract. 2021;75(3):e13746. https://doi.org/10.1111/ijcp.13746
  • Han Q, Zheng B, Daines L, Sheikh A. Long-Term Sequelae of COVID-19: A Systematic Review and Meta-Analysis of One-Year Follow-Up Studies on Post-COVID Symptoms. Pathogens. 2022;11(2):269. https://doi.org/10.3390/pathogens11020269
  • Huang L, Yao Q, Gu X, et al. 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study. Lancet. 2021;398(10302):747-58. https://doi.org/10.1016/S0140-6736(21)01755-4
  • Su Y, Yuan D, Chen DG, et al. Multiple early factors anticipate post-acute COVID-19 sequelae. Cell. 2022;185(5):881-895.e20.
  • Fernández-de-Las-Peñas C, Guijarro C, Torres-Macho J, et al. Diabetes and the Risk of Long-term Post-COVID Symptoms. Diabetes. 2021;70(12):2917-292. https://doi.org/10.2337/db21-0329
  • Pavli A, Theodoridou M, Maltezou HC. Post-COVID Syndrome: Incidence, Clinical Spectrum, and Challenges for Primary Healthcare Professionals. Arch Med Res. 2021 Aug;52(6):575-581. https://doi.org/10.1016/j.arcmed.2021.03.010
  • Tleyjeh IM, Saddik B, AlSwaidan N, et al. Prevalence and predictors of Post-Acute COVID-19 Syndrome (PACS) after hospital discharge: A cohort study with 4 months median follow-up. PLoS One. 2021;16(12):e0260568. https://doi.org/10.1371/journal.pone.0260568
  • Anjana NKN, Annie TT, Siba S, Meenu MS, Chintha S, Anish TSN. Manifestations and risk factors of post COVID syndrome among COVID-19 patients presented with minimal symptoms - A study from Kerala, India. J Family Med Prim Care. 2021;10(11):4023-4029. https://doi.org/10.4103/jfmpc.jfmpc_851_21
  • Subramanian A, Nirantharakumar K, Hughes S, et al. Symptoms and risk factors for long COVID in non-hospitalized adults. Nat Med. 2022;28(8):1706-14. https://doi.org/10.1038/s41591-022-01909-w
  • Cirulli ET, Schiabor Barrett KM, Riffle S, et al. Long-term COVID-19 symptoms in a large unselected population. medRxiv. 2020.10.07.20208702. https://doi.org/10.1101/2020.10.07.20208702
  • Mahmoud N, Radwan N, Alkattan A, et al. Post-COVID-19 syndrome: nature of symptoms and associated factors. Z Gesundh Wiss. 2023 Jan 3:1-6.
  • Aminian A, Bena J, Pantalone KM, et al. Association of obesity with postacute sequelae of COVID-19. Diabetes Obes Metab. 2021;23(9):2183-8. https://doi.org/10.1111/dom.14454
  • Boscolo-Rizzo P, Guida F, Polesel J, et al. Sequelae in adults at 12 months after mild-to-moderate coronavirus disease 2019 (COVID-19). Int Forum Allergy Rhinol. 2021;11(12):1685-8. https://doi.org/10.1002/alr.22832
  • Maestre-Muniz MM, Arias A, Mata-Vazquez E, et al. Long-Term Outcomes of Patients with Coronavirus Disease 2019 at One Year after Hospital Discharge. J Clin Med. 2021;10(13):2945. https://doi.org/10.3390/jcm10132945
  • Zhang X, Wang F, Shen Y, et al. Symptoms and Health Outcomes Among Survivors of COVID-19 Infection 1 Year After Discharge From Hospitals in Wuhan, China. JAMA Netw Open. 2021;4(9):e2127403. https://doi.org/10.1001/jamanetworkopen.2021.27403a
There are 19 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Research Articles
Authors

Hasan Açık 0000-0002-7247-8164

Gülen Açık 0000-0003-4723-6523

Publication Date September 2, 2024
Submission Date December 30, 2023
Acceptance Date June 3, 2024
Published in Issue Year 2024 Volume: 15 Issue: 52

Cite

Vancouver Açık H, Açık G. Factors Associated with Post-COVID Syndrome Three Months After COVID-19. Interdiscip Med J. 2024;15(52):41-7.