FURTHER SESQUITERPENE LACTONES AND FLAVONES FROM Centaurea bruguierana

Yıl 1995, Cilt: 31 , 25 - 28, 09.09.2015

U. Sönmez*, F.m. Harraz**, S. Öksüz***

Öz

A further investigation of the aerial parts of Centaurea bruguierana
(DC.) Hand.-Mazz. afforded four sesquiterpene lactones namely, cnicin, 1 1,13-
dehydromelitensin, 8a-(5-hydroxy)-angeloyloxy-l l, 13-dehydromelitensin, 8a-
(3',4'-dihydroxyethy1)-acryloxy- 1 1,13-dehydromelitensin and five flavonoids;
eupatilin, 5-hydroxy-6,7,3',4'-tetramethoxyflavone, jaceosidin, pectolinarigenin
and cirsilineol. The'structures were determined by spectral methods especially
by high field NMR spectroscopy. In course of our research of the genus Ceiztaurea, we have examined Ceiztaui-ea blvguielmza (DC.) Hand.-Mazz. (Syrz. C. phllocephala Boiss.) a Saudi Arabian plant, which was distributed in Najid province of Saudi Arabia. The plant has been investigated previously by one of us, F.M. Harraz, and the presence of a germacranolide; cnicin, an eudesmanolide; 11,13-dehydromelitensin 8a-acetate and three flavonoids; circilineol, cirsimaritin and hispudilin 7-0-rutinoside were reported (1).

Anahtar Kelimeler

Centaurea bruguielmzu, Compositae, sesquiterpene lactones, flavones

FURTHER SESQUITERPENE LACTONES AND FLAVONES FROM Centaurea bruguierana

Öz

Centaurea bruguierana (DC.) Hand.-Mazz. bitkisinin toprak iistii luslmlanndan dort seskiterpen lakton; 1 1,13-dehydromelitensin, cnicin, 8a-(5-hidroksi)-angeloyiloksi- 1 1 , 13-dehidromelitensin 8a-(3',4'-dihidroksieti1)-akriloksi11,13-dehidromelitensin ve beg flavonoid bilegik, eupatilin, 5-hidroksi-6,7,3',4'- tetrametoksiflavon, jaceosidin, pectolinarigenin ve cirsilineol elde edilmigtir. Bilegiklerh yapllari spektroskopik yontemler ile agklanrn~g~

Centaurea bruguierana (DC.) Hand.-Mazz. bitkisinin toprak iistii luslmlanndan dort seskiterpen lakton; 1 1,13-dehydromelitensin, cnicin, 8a-(5-hidroksi)-angeloyiloksi- 1 1 , 13-dehidromelitensin 8a-(3',4'-dihidroksieti1)-akriloksi11,13-dehidromelitensin ve beg flavonoid bilegik, eupatilin, 5-hidroksi-6,7,3',4'- tetrametoksiflavon, jaceosidin, pectolinarigenin ve cirsilineol elde edilmigtir. Bilegiklerh yapllari spektroskopik yontemler ile agklanrn~g~

Anahtar Kelimeler

Centaurea bruguielmzu, Compositae, sesquiterpene lactones, flavones

Kaynakça

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