Seven new thiazole derivatives have been synthesized from the reaction of α-oxo-α-methyl-N-(phenyl/substituted) ethanehydrazonoyl chlorides (A) (1, 2), obtained from the reaction of diazonium salts of aniline. 4-iodoaniline, 4-bromoaniline, 4-toluidine and benzocaine with chloroacetone, and thiosemicarbazones of 4- methylbenzaldehyde, 4-fluorobenzaldehyde, and furfural. The structure of the end products were determined using analytical and spectral methods. Fungicidal, insecticidal, and plant growth regulating activity tests are being carried out at Sittingbourne Research Centre, UK.
Key words: α-hydrazonoyl halides, thiosemicarbazones, thiazoles, tautomerism.
Seven new thiazole derivatives have been synthesized from the reaction of α-oxo-α-methyl-N-(phenyl/substituted) ethanehydrazonoyl chlorides (A) (1, 2), obtained from the reaction of diazonium salts of aniline. 4-iodoaniline, 4-bromoaniline, 4-toluidine and benzocaine with chloroacetone, and thiosemicarbazones of 4- methylbenzaldehyde, 4-fluorobenzaldehyde, and furfural. The structure of the end products were determined using analytical and spectral methods. Fungicidal, insecticidal, and plant growth regulating activity tests are being carried out at Sittingbourne Research Centre, UK.
Key words: α-hydrazonoyl halides, thiosemicarbazones, thiazoles, tautomerism.
α-hydrazonoyl halides thiosemicarbazones thiazoles tautomerism.
Birincil Dil | İngilizce |
---|---|
Konular | Eczacılık ve İlaç Bilimleri |
Bölüm | Makaleler |
Yazarlar | |
Yayımlanma Tarihi | 9 Eylül 2015 |
Yayımlandığı Sayı | Yıl 1993 Cilt: 29 Sayı: 1 |