THE ROLE OF THE SEROTONERGIC SYSTEM IN THE "WET DOG" SHAKE BEHAVIOUR INDUCED BY SODIUM N-DIPROPYL ACETATE
Öz
It is known that experimental animals used in pharmacological research behave in
certain ways with the influence of various neurotransmitters in the central nervous
system. In this research, we have studied the effect of buspiron on the wet dog shake behaviour, with respect to its relationship with the serotonergic system, after the administration of n-dipropyl acetate which is used in the treatment of epilepsy and 5-hydroxytryptophan which is a serotonin precursor.
Key words: "Wet dog" shake, n-dipropyl acetate, serotonin, buspiron.
Anahtar Kelimeler
Kaynakça
- I. Winkter, A., et al., Fedn Proc. Fedn Am. Socs. Exp. Biol., 19,22 (1960).
- 2. Bedard, P., Pycock, C. D., Neuropltarmacology, 16,663 (1977).
- 3. de Boer, T., Metselaar, H. J., Bruinvels, D., Life Sci., 20,933 (1977).
- 4. Scolnick, P. et al., Br. J. Pharmacol., 86, 637 (1985).
- 5. Hwang, E. C., Van Woert, M. H., Neuropltarmacology, 18,391 (1979).
- 6. Fletcher, A., Harding, V., J. Pltarm. Pharntacol., 33,811 (1981).
- 7. Peroutka, S. J.. Pltarmacology & Toxicology, 67, 373 (1990).
- 8. Come, S. J., Pickering, R. W., Warner, B. T., Br. J. Pharmacol., 20,106 (1963).
- 9. Graharne-Smith, D. G., J. Nel~roclzem., 18,1053 (1971).
- 10. Klawaus, H. L. et d., Res. Conunrcn. Client. Path. Pliarnzac., 5,555 (1973).
- 11. Wei, E.,Life Sci., 12,385 (1973).
- 12. Prange, A. J. et al., ibid., 14,447 (1974).
- 13. Turski, W. A. et al., Plzurnzucology, 28, 112 (1984).
- 14. Peroutka, S. J. et al., J. Neuropsycliiatry, 1,253 (1989).
- 15. Goodwin, G. M., Green, A. R., Br. J. Plmrmacol.,84,743 (1985)
THE ROLE OF THE SEROTONERGIC SYSTEM IN THE "WET DOG" SHAKE BEHAVIOUR INDUCED BY SODIUM N-DIPROPYL ACETATE
Öz
It is known that experimental animals used in pharmacological research behave in
certain ways with the influence of various neurotransmitters in the central nervous
system. In this research, we have studied the effect of buspiron on the wet dog shake behaviour, with respect to its relationship with the serotonergic system, after the administration of n-dipropyl acetate which is used in the treatment of epilepsy and 5-hydroxytryptophan which is a serotonin precursor
Anahtar Kelimeler
Kaynakça
- I. Winkter, A., et al., Fedn Proc. Fedn Am. Socs. Exp. Biol., 19,22 (1960).
- 2. Bedard, P., Pycock, C. D., Neuropltarmacology, 16,663 (1977).
- 3. de Boer, T., Metselaar, H. J., Bruinvels, D., Life Sci., 20,933 (1977).
- 4. Scolnick, P. et al., Br. J. Pharmacol., 86, 637 (1985).
- 5. Hwang, E. C., Van Woert, M. H., Neuropltarmacology, 18,391 (1979).
- 6. Fletcher, A., Harding, V., J. Pltarm. Pharntacol., 33,811 (1981).
- 7. Peroutka, S. J.. Pltarmacology & Toxicology, 67, 373 (1990).
- 8. Come, S. J., Pickering, R. W., Warner, B. T., Br. J. Pharmacol., 20,106 (1963).
- 9. Graharne-Smith, D. G., J. Nel~roclzem., 18,1053 (1971).
- 10. Klawaus, H. L. et d., Res. Conunrcn. Client. Path. Pliarnzac., 5,555 (1973).
- 11. Wei, E.,Life Sci., 12,385 (1973).
- 12. Prange, A. J. et al., ibid., 14,447 (1974).
- 13. Turski, W. A. et al., Plzurnzucology, 28, 112 (1984).
- 14. Peroutka, S. J. et al., J. Neuropsycliiatry, 1,253 (1989).
- 15. Goodwin, G. M., Green, A. R., Br. J. Plmrmacol.,84,743 (1985)
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Eczacılık ve İlaç Bilimleri |
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 10 Eylül 2015 |
| Yayımlandığı Sayı | Yıl 1993 Cilt: 29 Sayı: 1 |